Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   AC731_RS11340 Genome accession   NZ_CP014646
Coordinates   2423067..2424461 (-) Length   464 a.a.
NCBI ID   WP_048706143.1    Uniprot ID   A0A127K6C9
Organism   Thauera humireducens strain SgZ-1     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2418067..2429461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AC731_RS11320 (AC731_011320) - 2418155..2419108 (-) 954 WP_048706136.1 XrtA-associated tyrosine autokinase -
  AC731_RS11325 (AC731_011325) - 2419123..2420670 (-) 1548 WP_004258392.1 XrtA system polysaccharide chain length determinant -
  AC731_RS11330 (AC731_011330) - 2420754..2421383 (-) 630 WP_048706138.1 XrtA/PEP-CTERM system exopolysaccharide export protein -
  AC731_RS11335 (AC731_011335) - 2421657..2423066 (+) 1410 WP_048706141.1 MBL fold metallo-hydrolase RNA specificity domain-containing protein -
  AC731_RS11340 (AC731_011340) pilR 2423067..2424461 (-) 1395 WP_048706143.1 sigma-54-dependent transcriptional regulator Regulator
  AC731_RS11345 (AC731_011345) - 2424458..2426053 (-) 1596 WP_048706145.1 sensor histidine kinase -
  AC731_RS11350 (AC731_011350) - 2426019..2426276 (-) 258 WP_048706148.1 PP0621 family protein -
  AC731_RS11355 (AC731_011355) - 2426441..2427598 (+) 1158 WP_048706150.1 pyridoxal phosphate-dependent aminotransferase -
  AC731_RS11360 (AC731_011360) mtnA 2427656..2428756 (+) 1101 WP_048706153.1 S-methyl-5-thioribose-1-phosphate isomerase -
  AC731_RS11365 (AC731_011365) - 2428753..2429436 (+) 684 WP_048706156.1 class II aldolase/adducin family protein -

Sequence

Protein


Download         Length: 464 a.a.        Molecular weight: 50825.11 Da        Isoelectric Point: 5.8758

>NTDB_id=172969 AC731_RS11340 WP_048706143.1 2423067..2424461(-) (pilR) [Thauera humireducens strain SgZ-1]
MTVTERRNRPDSIDVLVVDDEDDIRELIELSLMRMGLGCDTAGSVQEARALIERRRYRLCLTDMRLPDGDGLELVEFIQA
RQPSTPVAVITAFGSIETAIRALKLGAFDFVTKPVELKRLRELVTHALKLEPSAAVVAPGGRTLIGSSPAFLQLRAQAEK
LARNQAPVFIHGESGTGKEVIARLIHGLGARANGPFVPVNCGAISPELMESEFFGHRKGSFTGAATDKEGLFQAASGGTL
FLDEIGELPLAMQVKLLRAIQERAVRPVGAHAEEPVDVRILSASHQDLSRLVADGKFRQDLFFRINVITLRIPPLRERAE
DIPALAEHILARVAEREGGPPRRLSPAAMVALQRHDFPGNVRELENLLERACALCEGDEIGPDDIDLQPACFSSATARPD
ATAAETGSTAGADAVEHDGHDTEVERMRVLKALEDTRWNRSAAARNLGMTLRQLRYRLQKWGME

Nucleotide


Download         Length: 1395 bp        

>NTDB_id=172969 AC731_RS11340 WP_048706143.1 2423067..2424461(-) (pilR) [Thauera humireducens strain SgZ-1]
ATGACCGTCACCGAACGCCGCAATCGTCCCGATTCGATCGACGTCCTCGTGGTGGACGACGAGGACGACATCCGTGAACT
GATCGAGCTGTCCCTGATGCGCATGGGGCTGGGCTGTGACACGGCCGGTTCGGTGCAGGAGGCACGTGCGCTGATCGAGC
GTCGTCGCTACCGCCTGTGCCTGACCGACATGCGCCTGCCGGACGGCGACGGGCTCGAACTCGTCGAGTTCATCCAGGCG
CGCCAGCCGAGCACGCCGGTGGCCGTCATCACCGCGTTTGGCAGCATCGAGACCGCCATCCGTGCACTCAAGCTGGGTGC
GTTCGACTTCGTGACCAAGCCGGTCGAGCTCAAGCGCCTGCGGGAGCTCGTCACCCATGCCCTCAAGCTCGAGCCTTCGG
CTGCTGTCGTCGCGCCCGGCGGACGCACGCTGATCGGCAGTTCCCCCGCCTTCCTGCAGCTACGCGCGCAGGCCGAGAAG
CTCGCGCGCAACCAGGCGCCGGTCTTCATCCACGGCGAATCCGGCACCGGCAAGGAGGTCATCGCGCGTCTCATCCATGG
GCTCGGCGCGCGCGCCAACGGCCCCTTCGTGCCGGTGAATTGCGGTGCGATCTCGCCCGAACTGATGGAAAGCGAGTTCT
TCGGCCATCGCAAGGGCAGCTTCACCGGCGCAGCGACCGACAAGGAAGGGCTGTTCCAGGCCGCGAGCGGCGGCACGCTG
TTCCTGGACGAGATCGGCGAGCTGCCGCTGGCCATGCAGGTCAAGCTGCTGCGGGCGATCCAGGAGCGGGCCGTGCGGCC
CGTGGGCGCACATGCGGAGGAGCCCGTGGACGTGCGCATCCTGTCCGCCTCGCACCAGGACCTTTCCCGGCTCGTGGCCG
ATGGCAAGTTCCGTCAGGACCTCTTCTTCCGCATCAACGTGATCACGCTGCGCATCCCGCCGCTGCGCGAGCGCGCCGAG
GACATCCCTGCGCTGGCCGAGCACATCCTGGCCCGGGTCGCCGAGCGCGAAGGCGGCCCGCCGCGCCGGCTTTCCCCGGC
GGCGATGGTCGCGCTGCAGCGCCATGATTTTCCGGGCAACGTGCGCGAACTCGAGAACCTGCTCGAGCGCGCCTGCGCGC
TGTGCGAAGGCGACGAGATCGGGCCGGACGACATCGACCTGCAGCCGGCCTGCTTTTCCTCTGCGACCGCCAGGCCCGAC
GCAACCGCAGCCGAGACTGGCTCCACGGCTGGGGCGGATGCTGTCGAGCATGACGGTCACGACACCGAGGTCGAGCGCAT
GCGGGTGCTCAAGGCGCTGGAGGATACGCGCTGGAACCGTTCGGCGGCGGCGCGCAATCTGGGCATGACCCTGCGCCAGT
TGCGCTACCGCCTGCAGAAGTGGGGCATGGAGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(15-124)

Sigma-54 interaction domain (Sigma54_activat)

(144-310)

Bacterial regulatory protein, Fis family (HTH_8)

(423-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A127K6C9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

60.134

96.767

0.582
  pilR Acinetobacter baumannii strain A118

50.759

99.353

0.504

Multiple sequence alignment