Detailed information NTG0172828

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: BMJ42_RS10660
• Genome accession: NZ_CP018136
• Coordinates: 1925285..1926184 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904870.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SP49
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1920285..1931184

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BMJ42_RS10635 (BMJ42_02018)	rsmA	1920615..1921487 (-)	873	WP_001216877.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
BMJ42_RS10640 (BMJ42_02019)	-	1921618..1921926 (-)	309	WP_000333257.1	hypothetical protein	-
BMJ42_RS10645 (BMJ42_02020)	-	1921919..1922560 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
BMJ42_RS10650 (BMJ42_02021)	-	1922562..1924592 (-)	2031	WP_000825278.1	bacteriocin-associated integral membrane family protein	-
BMJ42_RS10655 (BMJ42_02022)	-	1924669..1924965 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
BMJ42_RS10660 (BMJ42_02023)	comR	1925285..1926184 (-)	900	WP_000904870.1	helix-turn-helix transcriptional regulator	Regulator
BMJ42_RS10665 (BMJ42_02024)	rnmV	1926256..1926816 (-)	561	WP_000660015.1	ribonuclease M5	-
BMJ42_RS10670 (BMJ42_02025)	-	1926816..1927589 (-)	774	WP_000575621.1	TatD family hydrolase	-
BMJ42_RS10680 (BMJ42_02026)	-	1927885..1928613 (-)	729	Protein_1980	DUF1542 domain-containing protein	-
BMJ42_RS10685 (BMJ42_02027)	rpmH	1928822..1928956 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
BMJ42_RS10690 (BMJ42_02028)	-	1929101..1930315 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
BMJ42_RS10695 (BMJ42_02029)	-	1930471..1930764 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35351.12 Da
• Isoelectric Point: 4.8336

>NTDB_id=172828 BMJ42_RS10660 WP_000904870.1 1925285..1926184(-) (comR) [Streptococcus pneumoniae strain SP49]
MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=172828 BMJ42_RS10660 WP_000904870.1 1925285..1926184(-) (comR) [Streptococcus pneumoniae strain SP49]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAGTTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361