Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AZE34_RS09595 Genome accession   NZ_CP014567
Coordinates   1946123..1946752 (+) Length   209 a.a.
NCBI ID   WP_002450048.1    Uniprot ID   A0A1L8Y4G9
Organism   Staphylococcus hominis strain C34847     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1941123..1951752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AZE34_RS09565 (AZE34_09365) - 1941389..1942378 (-) 990 WP_017175232.1 FUSC family protein -
  AZE34_RS09570 (AZE34_09370) map 1942552..1943304 (+) 753 WP_017175231.1 type I methionyl aminopeptidase -
  AZE34_RS09580 (AZE34_09375) - 1943981..1944367 (+) 387 WP_017175230.1 hypothetical protein -
  AZE34_RS09585 (AZE34_09380) liaF 1944389..1945090 (+) 702 WP_017175229.1 cell wall-active antibiotics response protein LiaF -
  AZE34_RS09590 (AZE34_09385) vraS 1945087..1946121 (+) 1035 WP_017175228.1 sensor histidine kinase Regulator
  AZE34_RS09595 (AZE34_09390) vraR 1946123..1946752 (+) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  AZE34_RS09600 (AZE34_09395) - 1946831..1948033 (-) 1203 WP_017175227.1 YihY/virulence factor BrkB family protein -
  AZE34_RS09605 (AZE34_09400) - 1948125..1948406 (-) 282 WP_002450075.1 hypothetical protein -
  AZE34_RS09610 (AZE34_09405) - 1948412..1948876 (-) 465 WP_017175226.1 low molecular weight protein-tyrosine-phosphatase -
  AZE34_RS09615 (AZE34_09410) - 1949018..1949224 (+) 207 WP_002450082.1 DUF1128 domain-containing protein -
  AZE34_RS09620 (AZE34_09415) - 1949236..1950483 (+) 1248 WP_017175225.1 aminopeptidase -
  AZE34_RS09625 (AZE34_09420) - 1950516..1951049 (+) 534 WP_017175224.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23592.26 Da        Isoelectric Point: 5.3673

>NTDB_id=172520 AZE34_RS09595 WP_002450048.1 1946123..1946752(+) (vraR) [Staphylococcus hominis strain C34847]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLVKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=172520 AZE34_RS09595 WP_002450048.1 1946123..1946752(+) (vraR) [Staphylococcus hominis strain C34847]
ATGACGATTAAAGTATTATTTGTAGACGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGAGAAGGATCATCAGGAAAAGAGGCAATTGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCATATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGAGCACTTGATGCAGGGGTGGATAGTTATATATTAAAAACGAC
AAGTGCCAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCTGTATTCGAGCCAGAAGTTTTAGTAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Y4G9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment