Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BMR72_RS02245 Genome accession   NZ_CP017969
Coordinates   447824..448468 (-) Length   214 a.a.
NCBI ID   WP_003085214.1    Uniprot ID   A0A0H2ZLY6
Organism   Pseudomonas aeruginosa isolate B10W     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 442824..453468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BMR72_RS02215 (BMR72_02150) - 443232..444332 (+) 1101 WP_003129221.1 pyocin knob domain-containing protein -
  BMR72_RS02220 (BMR72_02155) - 444332..444643 (+) 312 WP_023094501.1 hypothetical protein -
  BMR72_RS02225 (BMR72_02160) - 444640..444867 (+) 228 WP_003129222.1 hypothetical protein -
  BMR72_RS02230 (BMR72_02165) - 445273..445878 (+) 606 WP_003129224.1 aminodeoxychorismate/anthranilate synthase component II -
  BMR72_RS02235 (BMR72_02170) trpD 445880..446929 (+) 1050 WP_003085203.1 anthranilate phosphoribosyltransferase -
  BMR72_RS02240 (BMR72_02175) trpC 446926..447762 (+) 837 WP_003129225.1 indole-3-glycerol phosphate synthase TrpC -
  BMR72_RS02245 (BMR72_02180) crp 447824..448468 (-) 645 WP_003085214.1 cAMP-activated global transcriptional regulator CRP Regulator
  BMR72_RS02250 (BMR72_02185) - 448739..449161 (+) 423 WP_003085219.1 OsmC family protein -
  BMR72_RS02255 (BMR72_02190) speD 449481..450275 (+) 795 WP_003085223.1 adenosylmethionine decarboxylase -
  BMR72_RS02260 (BMR72_02195) coq7 450330..450977 (-) 648 WP_003085224.1 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase -
  BMR72_RS02265 (BMR72_02200) - 451077..451415 (-) 339 WP_003129226.1 histidine triad nucleotide-binding protein -
  BMR72_RS02270 (BMR72_02205) - 451494..452975 (+) 1482 WP_003129227.1 AAA family ATPase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24225.01 Da        Isoelectric Point: 8.0525

>NTDB_id=172216 BMR72_RS02245 WP_003085214.1 447824..448468(-) (crp) [Pseudomonas aeruginosa isolate B10W]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=172216 BMR72_RS02245 WP_003085214.1 447824..448468(-) (crp) [Pseudomonas aeruginosa isolate B10W]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGTGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTGGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGAAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(22-114)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZLY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

67.327

94.393

0.636
  crp Haemophilus influenzae Rd KW20

60.396

94.393

0.57
  crp Acinetobacter baumannii D1279779

54.545

92.523

0.505

Multiple sequence alignment