Detailed information NTG0170956

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AB454_RS08735
• Genome accession: NZ_CP017680
• Coordinates: 1751003..1751992 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain CFSAN007851
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1746003..1756992

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB454_RS08720 (AB454_08535)	acsA	1747204..1748910 (-)	1707	WP_000862075.1	acetate--CoA ligase	-
AB454_RS08725 (AB454_08540)	-	1749079..1749711 (+)	633	WP_001016005.1	GNAT family N-acetyltransferase	-
AB454_RS08730 (AB454_08545)	-	1749736..1750905 (+)	1170	WP_001184010.1	acetoin utilization protein AcuC	-
AB454_RS08735 (AB454_08550)	ccpA	1751003..1751992 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
AB454_RS08740 (AB454_08555)	-	1752065..1752178 (-)	114	WP_001788994.1	hypothetical protein	-
AB454_RS08745 (AB454_08560)	-	1752532..1753623 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
AB454_RS08750 (AB454_08565)	-	1754084..1754167 (-)	84	WP_031789490.1	hypothetical protein	-
AB454_RS08755 (AB454_08570)	-	1754323..1755687 (-)	1365	WP_000193959.1	hypothetical protein	-
AB454_RS08760 (AB454_08575)	-	1755761..1756252 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=170956 AB454_RS08735 WP_000219066.1 1751003..1751992(-) (ccpA) [Staphylococcus aureus strain CFSAN007851]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=170956 AB454_RS08735 WP_000219066.1 1751003..1751992(-) (ccpA) [Staphylococcus aureus strain CFSAN007851]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462