Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA3   Type   Regulator
Locus tag   AXE83_RS06820 Genome accession   NZ_CP014264
Coordinates   1447864..1449831 (-) Length   655 a.a.
NCBI ID   WP_060955886.1    Uniprot ID   A0A1E9ZYC1
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   binding to XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1429863..1456433 1447864..1449831 within 0


Gene organization within MGE regions


Location: 1429863..1456433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS06700 (AXE83_06700) - 1429863..1430900 (+) 1038 WP_060955872.1 hypothetical protein -
  AXE83_RS06705 (AXE83_06705) - 1430993..1431994 (+) 1002 WP_060955873.1 hypothetical protein -
  AXE83_RS11260 - 1432009..1432182 (+) 174 WP_190279308.1 hypothetical protein -
  AXE83_RS06710 (AXE83_06710) - 1432281..1432916 (+) 636 WP_060955874.1 recombinase family protein -
  AXE83_RS06715 (AXE83_06715) - 1433167..1433559 (+) 393 WP_000523900.1 hypothetical protein -
  AXE83_RS11265 - 1433578..1433748 (+) 171 WP_190279309.1 hypothetical protein -
  AXE83_RS06720 (AXE83_06720) - 1433768..1434223 (+) 456 WP_060955875.1 hypothetical protein -
  AXE83_RS06725 (AXE83_06725) - 1434223..1434612 (+) 390 WP_060955876.1 hypothetical protein -
  AXE83_RS06730 (AXE83_06730) - 1434631..1434963 (+) 333 WP_060955877.1 hypothetical protein -
  AXE83_RS06735 (AXE83_06735) - 1434965..1435144 (+) 180 WP_060955878.1 hypothetical protein -
  AXE83_RS10650 - 1435487..1435684 (-) 198 Protein_1342 amino acid permease -
  AXE83_RS06745 (AXE83_06745) sufB 1435810..1437222 (-) 1413 WP_006151262.1 Fe-S cluster assembly protein SufB -
  AXE83_RS06750 (AXE83_06750) - 1437289..1437720 (-) 432 WP_049525872.1 SUF system NifU family Fe-S cluster assembly protein -
  AXE83_RS06755 (AXE83_06755) - 1437707..1438933 (-) 1227 WP_060955879.1 cysteine desulfurase -
  AXE83_RS06760 (AXE83_06760) sufD 1438944..1440206 (-) 1263 WP_060955880.1 Fe-S cluster assembly protein SufD -
  AXE83_RS06765 (AXE83_06765) sufC 1440234..1441004 (-) 771 WP_049503774.1 Fe-S cluster assembly ATPase SufC -
  AXE83_RS06770 (AXE83_06770) - 1441157..1441351 (-) 195 WP_049525865.1 DUF3272 family protein -
  AXE83_RS06775 (AXE83_06775) dnaX 1441374..1443038 (-) 1665 WP_060955881.1 DNA polymerase III subunit gamma/tau -
  AXE83_RS06780 (AXE83_06780) - 1443038..1443535 (-) 498 WP_060955882.1 GAF domain-containing protein -
  AXE83_RS06785 (AXE83_06785) rpsA 1443621..1444823 (-) 1203 WP_001001618.1 30S ribosomal protein S1 -
  AXE83_RS06800 (AXE83_06800) - 1445197..1445427 (-) 231 WP_000037108.1 DUF2969 domain-containing protein -
  AXE83_RS06805 (AXE83_06805) pcp 1445562..1446206 (-) 645 WP_060955883.1 pyroglutamyl-peptidase I -
  AXE83_RS06810 (AXE83_06810) - 1446220..1447143 (-) 924 WP_060955884.1 DUF979 family protein -
  AXE83_RS06815 (AXE83_06815) - 1447140..1447829 (-) 690 WP_060955885.1 DUF969 family protein -
  AXE83_RS06820 (AXE83_06820) amiA3 1447864..1449831 (-) 1968 WP_060955886.1 peptide ABC transporter substrate-binding protein Regulator
  AXE83_RS06825 (AXE83_06825) - 1449853..1450875 (-) 1023 WP_060955887.1 branched-chain amino acid aminotransferase -
  AXE83_RS06830 (AXE83_06830) parC 1451000..1453477 (-) 2478 WP_083500999.1 DNA topoisomerase IV subunit A -
  AXE83_RS06835 (AXE83_06835) - 1453672..1454514 (-) 843 WP_060955889.1 aminoglycoside 6-adenylyltransferase -
  AXE83_RS06840 (AXE83_06840) - 1454631..1455314 (-) 684 WP_060955890.1 hypothetical protein -
  AXE83_RS06845 (AXE83_06845) - 1455396..1456433 (-) 1038 WP_060955891.1 hypothetical protein -

Sequence

Protein


Download         Length: 655 a.a.        Molecular weight: 72820.43 Da        Isoelectric Point: 5.1245

>NTDB_id=170005 AXE83_RS06820 WP_060955886.1 1447864..1449831(-) (amiA3) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MKTKKWMLTAGVVLSTAVLLVACGKADKEADAPTTFSYVYGVDPSSLDYSIATRTSTTDIIGNVVDGLLENDEYGNLIPS
LAEDWSVSQDGLTYTYKLRKGVKWYTSEGEEYAEVTAHDFVTGLKHVADGKSDGVTLIQNSIKGLNEYMTGETNDFSTVG
VKAVDDYTVEYTLNAPETFWNSKVTSATMLPVNEEFLKASGKNYGTVSPAGILYNGPYILKTLTSKSLIEYEKNPNYWDK
EKVKIEKVKLTYYDGSDQESLIRSFSSGVYTTARLFPSSSNFASTLEQYGDKITYSPQDSTSYYFTFNVNRQSFNKTAKT
SEEQKTSTKEAMLNKDFRQAINFAFNRHSYAAQLNGEDGADKIIRNSLVPDNFVQSGGKNFGDIAQKELVNYGDQWKGVE
LVDGKDTIYNPDKAKASFEKAKKELEAKGVTFPIHLDVPVEQTNTIAVQQSNSFKQSIESTLGSENVVIDVLQMTDNEKE
SITSQARVPAQKDYDLNNTGWAPSYQDPASYLNIMDPKTGSAMKHLGITKGKDKEVVAQLGLDQYKKLLDDAVSETNDLN
KRYEKYAKAQAWLTDSSLLIPTASSGGSPVVSNIVPFSKPYSQVGIKGDPYIFKGMKLQKEIVTAKEYQAALEKWQKEKL
ESNNKYQKELESHVK

Nucleotide


Download         Length: 1968 bp        

>NTDB_id=170005 AXE83_RS06820 WP_060955886.1 1447864..1449831(-) (amiA3) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGAAAACGAAAAAGTGGATGTTAACAGCAGGAGTGGTCCTGAGTACAGCAGTTCTTCTTGTAGCTTGTGGTAAAGCCGA
CAAGGAAGCAGATGCGCCTACAACTTTCTCTTATGTCTATGGAGTAGACCCATCATCTTTGGACTACAGTATCGCAACTC
GTACTTCAACAACTGATATCATCGGTAACGTCGTTGATGGTTTGTTGGAAAACGATGAATATGGGAATTTGATTCCTTCC
CTCGCTGAGGATTGGAGTGTCTCACAAGACGGTTTGACTTATACTTATAAACTTCGTAAAGGGGTTAAATGGTACACGTC
AGAAGGTGAAGAATACGCTGAAGTAACTGCGCATGACTTTGTTACTGGATTGAAACACGTAGCTGATGGCAAATCAGACG
GTGTCACTCTTATTCAAAACTCAATTAAGGGCTTGAATGAATATATGACTGGTGAGACTAACGACTTCTCAACAGTTGGA
GTTAAGGCAGTGGATGATTATACTGTTGAGTACACTCTAAACGCACCTGAAACTTTCTGGAATTCCAAAGTAACTTCAGC
AACTATGTTGCCAGTAAATGAAGAATTTCTCAAAGCATCAGGTAAAAATTACGGAACGGTCAGCCCAGCAGGTATTCTTT
ATAATGGTCCATATATCCTGAAGACATTGACTTCAAAATCTTTAATCGAATATGAAAAGAACCCAAATTATTGGGATAAA
GAGAAGGTTAAAATCGAGAAAGTTAAATTAACTTACTATGATGGATCAGACCAAGAATCCTTGATCCGTAGCTTCTCTTC
AGGTGTTTACACAACAGCTCGCCTCTTCCCAAGTAGCTCAAACTTTGCTTCTACTTTGGAACAATACGGGGATAAAATTA
CCTATAGTCCACAGGATTCAACTAGTTACTACTTTACCTTTAACGTAAACCGTCAATCTTTCAATAAGACAGCGAAAACA
AGTGAAGAACAGAAAACTTCTACAAAAGAAGCAATGCTGAACAAGGACTTCCGTCAAGCCATCAACTTTGCCTTCAACCG
TCATTCTTATGCTGCCCAACTCAATGGTGAAGATGGTGCGGACAAGATTATTCGTAACAGCTTAGTACCAGATAACTTTG
TACAATCTGGTGGTAAAAACTTTGGTGATATCGCTCAAAAAGAATTGGTCAACTATGGAGACCAATGGAAAGGTGTTGAG
CTCGTCGACGGAAAAGATACCATCTACAATCCTGACAAAGCCAAAGCTTCATTTGAAAAAGCTAAGAAAGAGTTGGAAGC
AAAAGGTGTAACCTTCCCAATTCACTTGGATGTCCCAGTTGAACAGACAAATACAATTGCTGTTCAGCAAAGCAATTCCT
TCAAGCAATCAATCGAATCAACTCTTGGTTCTGAAAATGTCGTCATCGATGTCCTTCAAATGACTGACAATGAAAAGGAA
AGTATTACATCACAAGCGCGTGTTCCTGCTCAAAAAGACTATGATTTGAATAATACTGGATGGGCTCCAAGTTATCAAGA
CCCAGCAAGTTATCTCAATATCATGGATCCTAAGACCGGTTCTGCTATGAAACACCTTGGTATTACTAAAGGAAAAGACA
AGGAAGTAGTAGCTCAACTTGGTTTAGACCAATATAAGAAACTCCTAGATGATGCAGTTTCTGAGACAAACGATTTGAAT
AAGAGATATGAAAAATATGCTAAAGCCCAAGCTTGGCTCACAGATAGCTCTCTCTTGATACCGACAGCCTCATCAGGTGG
TTCACCAGTTGTCAGCAACATCGTTCCTTTCTCAAAACCATACTCACAAGTTGGTATTAAGGGTGATCCATACATCTTCA
AGGGAATGAAATTGCAAAAAGAGATTGTAACTGCTAAAGAATATCAAGCAGCTCTTGAAAAATGGCAAAAAGAAAAATTG
GAATCAAACAATAAATACCAAAAAGAACTAGAAAGTCATGTCAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(77-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E9ZYC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA3 Streptococcus thermophilus LMD-9

52.273

100

0.527
  amiA Streptococcus salivarius strain HSISS4

52.128

100

0.524
  amiA3 Streptococcus thermophilus LMG 18311

51.667

100

0.521

Multiple sequence alignment