Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WH25_RS03885 Genome accession   NZ_CP017295
Coordinates   815423..816055 (+) Length   210 a.a.
NCBI ID   WP_046165169.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 810423..821055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS03865 (WH25_03865) - 810965..811705 (+) 741 WP_045506058.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  WH25_RS03870 (WH25_03870) stkP 811702..813549 (+) 1848 WP_046165167.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  WH25_RS03875 (WH25_03875) liaF 813725..814423 (+) 699 WP_046165201.1 cell wall-active antibiotics response protein LiaF -
  WH25_RS03880 (WH25_03880) - 814420..815421 (+) 1002 WP_046165168.1 sensor histidine kinase -
  WH25_RS03885 (WH25_03885) vraR 815423..816055 (+) 633 WP_046165169.1 response regulator transcription factor Regulator
  WH25_RS03890 (WH25_03890) - 816143..817546 (+) 1404 WP_046165170.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  WH25_RS03895 (WH25_03895) - 817543..817929 (+) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -
  WH25_RS03900 (WH25_03900) cysK 817964..818893 (-) 930 WP_046165171.1 cysteine synthase A -
  WH25_RS03905 (WH25_03905) - 818991..819623 (-) 633 WP_046165172.1 YigZ family protein -
  WH25_RS03910 (WH25_03910) comFA/cflA 819679..820980 (+) 1302 WP_046165173.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23778.31 Da        Isoelectric Point: 4.8067

>NTDB_id=167977 WH25_RS03885 WP_046165169.1 815423..816055(+) (vraR) [Streptococcus gordonii strain IE35]
MKILLVDDHEMVRLGLKSYLDLQADVEVVAESSNGREGVEQALELRPDVIIMDIVMPEMNGIEATMAILETWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADEILHAVRKVARGEIAIETEVSKKVQYHRNHIELHDDLTARERDILGLLAKGY
ENQRIADELYISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=167977 WH25_RS03885 WP_046165169.1 815423..816055(+) (vraR) [Streptococcus gordonii strain IE35]
ATGAAAATTTTATTAGTAGATGATCACGAAATGGTTCGTTTGGGCTTAAAAAGCTACCTAGACTTACAAGCAGATGTTGA
AGTGGTGGCAGAAAGTTCTAATGGCCGTGAGGGAGTTGAGCAGGCTTTGGAGCTGAGACCAGATGTCATCATCATGGATA
TTGTTATGCCAGAGATGAATGGTATCGAGGCTACTATGGCTATTCTAGAAACTTGGCCAGAGGCAAAAATTTTGATTTTG
ACTTCCTACTTGGATAATGAAAAGATTTATCCTGTTCTGGATGCGGGAGCTAAAGGTTACATGCTGAAGACATCTAGTGC
AGATGAGATCTTACATGCTGTCCGAAAAGTAGCTAGAGGAGAAATTGCGATTGAAACAGAAGTCAGTAAAAAAGTTCAGT
ACCATCGCAATCACATTGAATTACATGATGATTTAACCGCTCGAGAACGAGATATTTTGGGGCTTCTAGCCAAGGGATAT
GAAAATCAACGCATTGCTGATGAGCTTTATATTTCTCTAAAAACAGTAAAAACTCATGTTTCTAATATCTTGTCAAAATT
GGAAGTGAGTGACCGGACTCAAGCGGTTGTTTATGCCTTTCAGCATCACTTAGTTCCTCAGGAAGACTTCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

98.095

0.533
  degU Bacillus subtilis subsp. subtilis str. 168

40.179

100

0.429

Multiple sequence alignment