Detailed information NTG0167492

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AL510_RS01560
• Genome accession: NZ_CP014027
• Coordinates: 327014..328015 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain FDAARGOS_149
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 322014..333015

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AL510_RS01545 (AL510_01505)	thrS	322184..324127 (-)	1944	WP_010921984.1	threonine--tRNA ligase	-
AL510_RS01550 (AL510_01510)	-	324549..325883 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
AL510_RS01555 (AL510_01515)	-	325885..326883 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
AL510_RS01560 (AL510_01520)	ccpA	327014..328015 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
AL510_RS01565 (AL510_01525)	-	328189..329274 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
AL510_RS01570 (AL510_01530)	-	329323..329988 (+)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
AL510_RS01575 (AL510_01535)	-	329999..330376 (+)	378	WP_002985686.1	VOC family protein	-
AL510_RS01580 (AL510_01540)	-	330521..331447 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
AL510_RS01585 (AL510_01545)	-	331658..332341 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=167492 AL510_RS01560 WP_002985680.1 327014..328015(-) (ccpA) [Streptococcus pyogenes strain FDAARGOS_149]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=167492 AL510_RS01560 WP_002985680.1 327014..328015(-) (ccpA) [Streptococcus pyogenes strain FDAARGOS_149]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559