Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AL483_RS15220 Genome accession   NZ_CP014016
Coordinates   499386..500015 (+) Length   209 a.a.
NCBI ID   WP_002481662.1    Uniprot ID   -
Organism   Staphylococcus simulans strain FDAARGOS_124     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 494386..505015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AL483_RS15195 (AL483_02470) - 495158..496144 (-) 987 WP_002481667.1 FUSC family protein -
  AL483_RS15200 (AL483_02475) map 496364..497128 (+) 765 WP_002481666.1 type I methionyl aminopeptidase -
  AL483_RS15205 (AL483_02480) - 497244..497639 (+) 396 WP_002481665.1 hypothetical protein -
  AL483_RS15210 (AL483_02485) liaF 497655..498356 (+) 702 WP_061054663.1 cell wall-active antibiotics response protein LiaF -
  AL483_RS15215 (AL483_02490) vraS 498353..499396 (+) 1044 WP_002481663.1 sensor histidine kinase Regulator
  AL483_RS15220 (AL483_02495) vraR 499386..500015 (+) 630 WP_002481662.1 response regulator transcription factor Regulator
  AL483_RS15225 (AL483_02500) - 500086..500664 (-) 579 WP_002481661.1 beta-class carbonic anhydrase -
  AL483_RS15230 (AL483_02505) - 500873..501949 (-) 1077 WP_002481660.1 YihY/virulence factor BrkB family protein -
  AL483_RS15235 (AL483_02510) - 502080..502370 (-) 291 WP_002481659.1 hypothetical protein -
  AL483_RS15240 (AL483_02515) - 502378..502842 (-) 465 WP_002481658.1 low molecular weight protein-tyrosine-phosphatase -
  AL483_RS15245 (AL483_02520) - 503066..503272 (+) 207 WP_002481657.1 DUF1128 family protein -
  AL483_RS15250 (AL483_02525) - 503309..504547 (+) 1239 WP_002481656.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23719.32 Da        Isoelectric Point: 4.6245

>NTDB_id=167229 AL483_RS15220 WP_002481662.1 499386..500015(+) (vraR) [Staphylococcus simulans strain FDAARGOS_124]
MAIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELQPDLILMDLLMEDMDGVEATMQIKKDLPQIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTYRNEAVFEAEVLVKMRNRMNQRAELYELLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=167229 AL483_RS15220 WP_002481662.1 499386..500015(+) (vraR) [Staphylococcus simulans strain FDAARGOS_124]
ATGGCGATTAAAGTATTATTTGTCGATGACCACGAAATGGTTCGTATCGGCATCTCAAGTTATTTATCTACACAACCTGA
TATCGAAGTCGTCGGGGAAGGCAAATCAGGTAAAGAAGCAATTGAAAAAGCTCATGAATTGCAGCCTGATTTAATCTTGA
TGGATTTGTTGATGGAAGACATGGATGGCGTAGAAGCTACAATGCAGATTAAAAAAGATTTACCTCAGATTAAAGTATTG
ATGCTGACAAGTTATATTGAGGATAATGAAGTGTATCGTGCTTTAGACGCTGGGGTAGACAGTTATATTCTAAAAACGAC
GAGCGCAAGTGATATCGCAGAAGCGATTCGTAAAACATATCGTAACGAAGCGGTGTTTGAAGCGGAAGTACTTGTTAAAA
TGCGTAATCGCATGAATCAACGTGCTGAATTATATGAATTATTAACAGATAGAGAAATGGAAATTTTATTGTTAATCGCA
AAAGGTTATTCTAACCAAGAAATCGCCAGTGCGTCACATATTACGATTAAAACAGTTAAAACACATGTGAGTAATATATT
AAGCAAGCTAGAAGTTCAAGACAGAACACAAGCTGTTATTTACGCATTCCAACACGATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment