Detailed information NTG0167228

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AL483_RS15215
• Genome accession: NZ_CP014016
• Coordinates: 498353..499396 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain FDAARGOS_124
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 493353..504396

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AL483_RS15190 (AL483_02465)	-	494356..495075 (+)	720	WP_002481668.1	type 1 glutamine amidotransferase	-
AL483_RS15195 (AL483_02470)	-	495158..496144 (-)	987	WP_002481667.1	FUSC family protein	-
AL483_RS15200 (AL483_02475)	map	496364..497128 (+)	765	WP_002481666.1	type I methionyl aminopeptidase	-
AL483_RS15205 (AL483_02480)	-	497244..497639 (+)	396	WP_002481665.1	hypothetical protein	-
AL483_RS15210 (AL483_02485)	liaF	497655..498356 (+)	702	WP_061054663.1	cell wall-active antibiotics response protein LiaF	-
AL483_RS15215 (AL483_02490)	vraS	498353..499396 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
AL483_RS15220 (AL483_02495)	vraR	499386..500015 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
AL483_RS15225 (AL483_02500)	-	500086..500664 (-)	579	WP_002481661.1	beta-class carbonic anhydrase	-
AL483_RS15230 (AL483_02505)	-	500873..501949 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
AL483_RS15235 (AL483_02510)	-	502080..502370 (-)	291	WP_002481659.1	hypothetical protein	-
AL483_RS15240 (AL483_02515)	-	502378..502842 (-)	465	WP_002481658.1	low molecular weight protein-tyrosine-phosphatase	-
AL483_RS15245 (AL483_02520)	-	503066..503272 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=167228 AL483_RS15215 WP_002481663.1 498353..499396(+) (vraS) [Staphylococcus simulans strain FDAARGOS_124]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=167228 AL483_RS15215 WP_002481663.1 498353..499396(+) (vraS) [Staphylococcus simulans strain FDAARGOS_124]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAGTTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGAGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862