Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BHT24_RS19220 Genome accession   NZ_CP017220
Coordinates   3662232..3662864 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain FAM21845     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3657232..3667864
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BHT24_RS19190 (BHT24_18390) yheS 3657401..3659314 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  BHT24_RS19195 (BHT24_18395) yheT 3659314..3660336 (+) 1023 WP_000057379.1 hydrolase -
  BHT24_RS19200 (BHT24_18400) yheU 3660330..3660548 (+) 219 WP_000907085.1 YheU family protein -
  BHT24_RS19205 (BHT24_18405) prkB 3660602..3661471 (+) 870 WP_001274680.1 phosphoribulokinase -
  BHT24_RS19210 (BHT24_18410) yhfA 3661526..3661930 (-) 405 WP_001148908.1 OsmC family protein -
  BHT24_RS19220 (BHT24_18420) crp 3662232..3662864 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BHT24_RS19225 (BHT24_18425) yhfK 3662915..3665005 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  BHT24_RS19230 (BHT24_18430) argD 3665072..3666292 (-) 1221 WP_000963787.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BHT24_RS19235 (BHT24_18435) pabA 3666378..3666941 (-) 564 WP_000601851.1 aminodeoxychorismate synthase component 2 -
  BHT24_RS19240 (BHT24_18440) fic 3666973..3667575 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  BHT24_RS19245 (BHT24_18445) yhfG 3667565..3667732 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=167073 BHT24_RS19220 WP_000242755.1 3662232..3662864(+) (crp) [Escherichia coli strain FAM21845]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=167073 BHT24_RS19220 WP_000242755.1 3662232..3662864(+) (crp) [Escherichia coli strain FAM21845]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467