Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | SE1UMMC_RS03155 | Genome accession | NZ_CP013943 |
| Coordinates | 611370..611945 (+) | Length | 191 a.a. |
| NCBI ID | WP_001829272.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain DAR1907 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 612346..654544 | 611370..611945 | flank | 401 |
Gene organization within MGE regions
Location: 611370..654544
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SE1UMMC_RS03155 (SE1UMMC_02925) | comK/comK1 | 611370..611945 (+) | 576 | WP_001829272.1 | competence protein ComK | Regulator |
| SE1UMMC_RS03170 (SE1UMMC_02940) | - | 612346..613395 (-) | 1050 | WP_101750498.1 | tyrosine-type recombinase/integrase | - |
| SE1UMMC_RS03175 (SE1UMMC_02945) | - | 613555..614223 (-) | 669 | WP_101750499.1 | hypothetical protein | - |
| SE1UMMC_RS03180 (SE1UMMC_02950) | - | 614241..614699 (-) | 459 | WP_002504200.1 | ImmA/IrrE family metallo-endopeptidase | - |
| SE1UMMC_RS03185 (SE1UMMC_02955) | - | 614721..615035 (-) | 315 | WP_002504199.1 | helix-turn-helix domain-containing protein | - |
| SE1UMMC_RS03190 (SE1UMMC_02960) | - | 615188..615400 (+) | 213 | WP_101750500.1 | helix-turn-helix transcriptional regulator | - |
| SE1UMMC_RS13910 | - | 615444..615584 (+) | 141 | WP_002485815.1 | hypothetical protein | - |
| SE1UMMC_RS03195 (SE1UMMC_02965) | - | 615577..615801 (-) | 225 | WP_002504198.1 | hypothetical protein | - |
| SE1UMMC_RS03200 (SE1UMMC_02970) | - | 615851..616591 (+) | 741 | WP_002504197.1 | phage repressor protein | - |
| SE1UMMC_RS03205 (SE1UMMC_02975) | - | 616604..616813 (+) | 210 | WP_001830281.1 | hypothetical protein | - |
| SE1UMMC_RS13915 | - | 616827..616973 (+) | 147 | WP_002484748.1 | hypothetical protein | - |
| SE1UMMC_RS03210 (SE1UMMC_02980) | - | 616960..617238 (-) | 279 | WP_002484728.1 | hypothetical protein | - |
| SE1UMMC_RS13920 | - | 617333..617509 (+) | 177 | WP_199559955.1 | hypothetical protein | - |
| SE1UMMC_RS03215 (SE1UMMC_02985) | - | 617571..617840 (+) | 270 | WP_101750501.1 | chordopoxvirus fusion protein | - |
| SE1UMMC_RS03220 (SE1UMMC_02990) | - | 617818..618069 (+) | 252 | WP_002485808.1 | hypothetical protein | - |
| SE1UMMC_RS03225 (SE1UMMC_02995) | - | 618062..618706 (+) | 645 | WP_002485844.1 | DUF1071 domain-containing protein | - |
| SE1UMMC_RS03230 (SE1UMMC_03000) | ssbA | 618696..619124 (+) | 429 | WP_101750502.1 | single-stranded DNA-binding protein | Machinery gene |
| SE1UMMC_RS03235 (SE1UMMC_03005) | - | 619138..619812 (+) | 675 | WP_002485820.1 | putative HNHc nuclease | - |
| SE1UMMC_RS03240 (SE1UMMC_03010) | - | 619964..620665 (+) | 702 | WP_101750503.1 | helix-turn-helix domain-containing protein | - |
| SE1UMMC_RS03245 (SE1UMMC_03015) | - | 620671..621024 (+) | 354 | WP_101750504.1 | hypothetical protein | - |
| SE1UMMC_RS03250 (SE1UMMC_03020) | - | 621014..622261 (+) | 1248 | WP_001830247.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| SE1UMMC_RS03255 (SE1UMMC_03025) | - | 622258..622479 (+) | 222 | WP_001830239.1 | hypothetical protein | - |
| SE1UMMC_RS03260 (SE1UMMC_03030) | - | 622457..622702 (+) | 246 | WP_002469496.1 | hypothetical protein | - |
| SE1UMMC_RS03265 (SE1UMMC_03035) | - | 622712..623125 (+) | 414 | WP_002469467.1 | DUF1064 domain-containing protein | - |
| SE1UMMC_RS03270 (SE1UMMC_03040) | - | 623112..623576 (+) | 465 | WP_002469486.1 | hypothetical protein | - |
| SE1UMMC_RS03275 (SE1UMMC_03045) | - | 623528..623719 (+) | 192 | WP_002469484.1 | hypothetical protein | - |
| SE1UMMC_RS03280 (SE1UMMC_03050) | - | 623720..624079 (+) | 360 | WP_101750505.1 | SA1788 family PVL leukocidin-associated protein | - |
| SE1UMMC_RS03285 (SE1UMMC_03055) | - | 624076..624519 (+) | 444 | WP_101750506.1 | DUF3310 domain-containing protein | - |
| SE1UMMC_RS03290 (SE1UMMC_03060) | - | 624467..625096 (+) | 630 | WP_099800579.1 | NUMOD4 domain-containing protein | - |
| SE1UMMC_RS03295 (SE1UMMC_03065) | - | 625099..625779 (+) | 681 | WP_101750507.1 | hypothetical protein | - |
| SE1UMMC_RS03300 (SE1UMMC_03070) | - | 625776..625961 (+) | 186 | WP_002500115.1 | hypothetical protein | - |
| SE1UMMC_RS03305 (SE1UMMC_03075) | - | 625949..626305 (+) | 357 | WP_418855211.1 | thermonuclease family protein | - |
| SE1UMMC_RS03310 (SE1UMMC_03080) | - | 626309..626608 (+) | 300 | WP_101750508.1 | hypothetical protein | - |
| SE1UMMC_RS03315 (SE1UMMC_03085) | - | 626598..626846 (+) | 249 | WP_001830273.1 | hypothetical protein | - |
| SE1UMMC_RS03320 (SE1UMMC_03090) | - | 626836..627015 (+) | 180 | WP_002504360.1 | DUF1024 family protein | - |
| SE1UMMC_RS03325 (SE1UMMC_03095) | - | 627008..627331 (+) | 324 | WP_101750509.1 | MazG-like family protein | - |
| SE1UMMC_RS03330 (SE1UMMC_03100) | - | 627342..627971 (+) | 630 | WP_142379577.1 | hypothetical protein | - |
| SE1UMMC_RS03335 (SE1UMMC_03105) | - | 628025..628345 (+) | 321 | WP_101750510.1 | hypothetical protein | - |
| SE1UMMC_RS03340 (SE1UMMC_03110) | - | 628365..628568 (+) | 204 | WP_101750511.1 | DUF1381 domain-containing protein | - |
| SE1UMMC_RS03345 (SE1UMMC_03115) | rinB | 628581..628748 (+) | 168 | WP_002504175.1 | transcriptional activator RinB | - |
| SE1UMMC_RS03350 | - | 628748..628897 (+) | 150 | WP_002500107.1 | DUF1514 family protein | - |
| SE1UMMC_RS03355 (SE1UMMC_03120) | - | 628914..629360 (+) | 447 | WP_002453536.1 | transcriptional regulator | - |
| SE1UMMC_RS03360 (SE1UMMC_03125) | - | 629956..630306 (+) | 351 | WP_049392021.1 | HNH endonuclease | - |
| SE1UMMC_RS03365 (SE1UMMC_03130) | - | 630478..630945 (+) | 468 | WP_002456394.1 | phage terminase small subunit P27 family | - |
| SE1UMMC_RS03370 (SE1UMMC_03135) | - | 630932..632626 (+) | 1695 | WP_002500103.1 | terminase large subunit | - |
| SE1UMMC_RS03375 (SE1UMMC_03140) | - | 632638..632832 (+) | 195 | WP_002500102.1 | hypothetical protein | - |
| SE1UMMC_RS03380 (SE1UMMC_03145) | - | 632832..634064 (+) | 1233 | WP_002485821.1 | phage portal protein | - |
| SE1UMMC_RS03385 (SE1UMMC_03150) | - | 634054..634611 (+) | 558 | WP_002485849.1 | HK97 family phage prohead protease | - |
| SE1UMMC_RS03390 (SE1UMMC_03155) | - | 634652..635995 (+) | 1344 | WP_002485824.1 | phage major capsid protein | - |
| SE1UMMC_RS03395 (SE1UMMC_03160) | - | 636014..636355 (+) | 342 | WP_002485829.1 | head-tail connector protein | - |
| SE1UMMC_RS03400 (SE1UMMC_03165) | - | 636345..636674 (+) | 330 | WP_002468167.1 | hypothetical protein | - |
| SE1UMMC_RS03405 (SE1UMMC_03170) | - | 636671..637075 (+) | 405 | WP_002485860.1 | hypothetical protein | - |
| SE1UMMC_RS03410 (SE1UMMC_03175) | - | 637080..637484 (+) | 405 | WP_002485830.1 | hypothetical protein | - |
| SE1UMMC_RS03415 (SE1UMMC_03180) | - | 637497..638126 (+) | 630 | WP_101750512.1 | major tail protein | - |
| SE1UMMC_RS03420 (SE1UMMC_03185) | - | 638145..638330 (+) | 186 | WP_002456405.1 | hypothetical protein | - |
| SE1UMMC_RS03425 (SE1UMMC_03190) | gpG | 638394..638756 (+) | 363 | WP_002456406.1 | phage tail assembly chaperone G | - |
| SE1UMMC_RS13785 | gpGT | 638789..638941 (+) | 153 | WP_002456407.1 | phage tail assembly chaperone GT | - |
| SE1UMMC_RS03430 (SE1UMMC_03195) | - | 638970..639962 (+) | 993 | Protein_635 | phage tail tape measure protein | - |
| SE1UMMC_RS03435 (SE1UMMC_03200) | - | 640081..641010 (+) | 930 | WP_101750513.1 | DUF2726 domain-containing protein | - |
| SE1UMMC_RS03440 (SE1UMMC_03205) | - | 641188..644970 (+) | 3783 | WP_233486917.1 | phage tail tape measure protein | - |
| SE1UMMC_RS03445 (SE1UMMC_03210) | - | 644972..645805 (+) | 834 | WP_002468177.1 | phage tail domain-containing protein | - |
| SE1UMMC_RS03450 (SE1UMMC_03215) | - | 645815..647374 (+) | 1560 | WP_194088047.1 | prophage endopeptidase tail family protein | - |
| SE1UMMC_RS13925 | - | 647367..647540 (+) | 174 | WP_002504159.1 | hypothetical protein | - |
| SE1UMMC_RS03455 (SE1UMMC_03220) | - | 647556..649418 (+) | 1863 | WP_101750515.1 | M14 family metallopeptidase | - |
| SE1UMMC_RS03460 (SE1UMMC_03225) | - | 649418..650632 (+) | 1215 | WP_101750516.1 | BppU family phage baseplate upper protein | - |
| SE1UMMC_RS03465 (SE1UMMC_03230) | - | 650637..651260 (+) | 624 | WP_032604283.1 | poly-gamma-glutamate hydrolase family protein | - |
| SE1UMMC_RS03470 (SE1UMMC_03235) | - | 651257..651682 (+) | 426 | WP_002499223.1 | hypothetical protein | - |
| SE1UMMC_RS03475 (SE1UMMC_03240) | - | 651669..652076 (+) | 408 | WP_101750517.1 | hypothetical protein | - |
| SE1UMMC_RS03480 (SE1UMMC_03245) | - | 652234..652632 (+) | 399 | WP_002499221.1 | YxeA family protein | - |
| SE1UMMC_RS03485 (SE1UMMC_03250) | - | 652696..653106 (+) | 411 | WP_002499220.1 | phage holin | - |
| SE1UMMC_RS03490 (SE1UMMC_03255) | - | 653081..654544 (+) | 1464 | WP_002499219.1 | SH3 domain-containing protein | - |
Sequence
Protein
Download Length: 191 a.a. Molecular weight: 22782.87 Da Isoelectric Point: 9.2887
>NTDB_id=166389 SE1UMMC_RS03155 WP_001829272.1 611370..611945(+) (comK/comK1) [Staphylococcus epidermidis strain DAR1907]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
Nucleotide
Download Length: 576 bp
>NTDB_id=166389 SE1UMMC_RS03155 WP_001829272.1 611370..611945(+) (comK/comK1) [Staphylococcus epidermidis strain DAR1907]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
76.757 |
96.859 |
0.743 |
| comK/comK1 | Staphylococcus aureus N315 |
76.757 |
96.859 |
0.743 |