Detailed information
Bioinformatically predicted
Overview
| Name | amiC | Type | Regulator |
| Locus tag | AVT04_RS07745 | Genome accession | NZ_CP013939 |
| Coordinates | 1446608..1448101 (+) | Length | 497 a.a. |
| NCBI ID | WP_011227407.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain S9 | ||
| Function | internalize XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1394799..1466578 | 1446608..1448101 | within | 0 |
Gene organization within MGE regions
Location: 1394799..1466578
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AVT04_RS07495 (AVT04_07495) | - | 1394897..1395637 (-) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
| AVT04_RS07500 (AVT04_07500) | - | 1395637..1397847 (-) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| AVT04_RS11520 | - | 1398046..1398982 (+) | 937 | Protein_1386 | CPBP family intramembrane glutamic endopeptidase | - |
| AVT04_RS07520 (AVT04_07520) | uvrB | 1399669..1401660 (+) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| AVT04_RS07525 (AVT04_07525) | - | 1401705..1402169 (+) | 465 | WP_011226345.1 | 8-oxo-dGTP diphosphatase | - |
| AVT04_RS07530 (AVT04_07530) | - | 1402383..1403213 (+) | 831 | WP_041828297.1 | transporter substrate-binding domain-containing protein | - |
| AVT04_RS07535 (AVT04_07535) | - | 1403210..1404007 (+) | 798 | WP_059257394.1 | transporter substrate-binding domain-containing protein | - |
| AVT04_RS07540 (AVT04_07540) | - | 1404354..1405463 (+) | 1110 | WP_041828295.1 | aminotransferase | - |
| AVT04_RS07545 (AVT04_07545) | - | 1405556..1406350 (+) | 795 | WP_011227442.1 | ABC transporter substrate-binding protein | - |
| AVT04_RS07550 (AVT04_07550) | - | 1406456..1407409 (-) | 954 | WP_041826943.1 | IS30 family transposase | - |
| AVT04_RS07555 (AVT04_07555) | rpsU | 1407790..1407966 (+) | 177 | WP_011226340.1 | 30S ribosomal protein S21 | - |
| AVT04_RS07560 (AVT04_07560) | dnaG | 1408338..1410149 (+) | 1812 | WP_011227441.1 | DNA primase | - |
| AVT04_RS07565 (AVT04_07565) | rpoD | 1410153..1411262 (+) | 1110 | WP_011227440.1 | RNA polymerase sigma factor RpoD | - |
| AVT04_RS07570 (AVT04_07570) | - | 1411316..1411651 (+) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| AVT04_RS07575 (AVT04_07575) | - | 1411661..1412587 (+) | 927 | WP_011227439.1 | glycosyltransferase family 2 protein | - |
| AVT04_RS07580 (AVT04_07580) | rfbD | 1412705..1413556 (+) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| AVT04_RS07585 (AVT04_07585) | - | 1413677..1414936 (+) | 1260 | WP_011227438.1 | oligosaccharide flippase family protein | - |
| AVT04_RS07590 (AVT04_07590) | - | 1414933..1415919 (+) | 987 | WP_011227437.1 | glycosyltransferase family 2 protein | - |
| AVT04_RS07595 (AVT04_07595) | - | 1415984..1416456 (+) | 473 | Protein_1402 | glycosyltransferase family 2 protein | - |
| AVT04_RS07600 (AVT04_07600) | - | 1416540..1417235 (+) | 696 | WP_173405413.1 | glycosyltransferase family 2 protein | - |
| AVT04_RS07605 (AVT04_07605) | - | 1417241..1417573 (+) | 333 | WP_011227433.1 | DUF2304 domain-containing protein | - |
| AVT04_RS07610 (AVT04_07610) | - | 1417574..1418356 (+) | 783 | WP_011227432.1 | glycosyltransferase family A protein | - |
| AVT04_RS07615 (AVT04_07615) | cps2T | 1418475..1419623 (+) | 1149 | WP_011227431.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| AVT04_RS07620 (AVT04_07620) | - | 1419620..1420561 (+) | 942 | WP_011227430.1 | glycosyltransferase family 2 protein | - |
| AVT04_RS07625 (AVT04_07625) | - | 1420561..1421367 (+) | 807 | WP_011227429.1 | ABC transporter permease | - |
| AVT04_RS07630 (AVT04_07630) | - | 1421367..1422569 (+) | 1203 | WP_059257395.1 | ABC transporter ATP-binding protein | - |
| AVT04_RS07635 (AVT04_07635) | - | 1422587..1424287 (+) | 1701 | WP_041827077.1 | glycosyltransferase family 4 protein | - |
| AVT04_RS07640 (AVT04_07640) | - | 1424289..1426034 (+) | 1746 | WP_011227426.1 | rhamnan synthesis F family protein | - |
| AVT04_RS07645 (AVT04_07645) | - | 1426183..1427523 (+) | 1341 | WP_231108743.1 | DUF2142 domain-containing protein | - |
| AVT04_RS07650 (AVT04_07650) | radC | 1427702..1428388 (+) | 687 | WP_011227424.1 | RadC family protein | - |
| AVT04_RS07655 (AVT04_07655) | - | 1428441..1429136 (-) | 696 | WP_011227423.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| AVT04_RS07660 (AVT04_07660) | - | 1429129..1429788 (-) | 660 | WP_041827076.1 | redox-sensing transcriptional repressor Rex | - |
| AVT04_RS07665 (AVT04_07665) | - | 1429932..1430279 (-) | 348 | WP_002948028.1 | DUF1831 domain-containing protein | - |
| AVT04_RS10435 (AVT04_07670) | - | 1430281..1431393 (-) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| AVT04_RS10440 (AVT04_07675) | - | 1431397..1432368 (-) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| AVT04_RS07680 (AVT04_07680) | - | 1432731..1433306 (-) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| AVT04_RS07685 (AVT04_07685) | - | 1433402..1434076 (+) | 675 | WP_002951443.1 | GTP pyrophosphokinase | - |
| AVT04_RS07690 (AVT04_07690) | - | 1434048..1434884 (+) | 837 | WP_041827075.1 | NAD kinase | - |
| AVT04_RS07695 (AVT04_07695) | - | 1434881..1435777 (+) | 897 | WP_011226316.1 | RluA family pseudouridine synthase | - |
| AVT04_RS07700 (AVT04_07700) | pta | 1435791..1436774 (+) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| AVT04_RS10810 | - | 1436860..1438212 (+) | 1353 | Protein_1424 | IS3 family transposase | - |
| AVT04_RS07715 (AVT04_07715) | - | 1438258..1439463 (-) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| AVT04_RS07720 (AVT04_07720) | - | 1439812..1440126 (+) | 315 | Protein_1426 | TatD family hydrolase | - |
| AVT04_RS11280 | - | 1440158..1440568 (+) | 411 | Protein_1427 | ATP-binding cassette domain-containing protein | - |
| AVT04_RS10090 | - | 1440562..1440752 (+) | 191 | Protein_1428 | IS3 family transposase | - |
| AVT04_RS07730 (AVT04_07730) | amiA3 | 1440956..1442929 (+) | 1974 | WP_059257396.1 | peptide ABC transporter substrate-binding protein | Regulator |
| AVT04_RS10095 | - | 1442974..1444223 (-) | 1250 | Protein_1430 | ISL3 family transposase | - |
| AVT04_RS07740 (AVT04_07740) | amiA | 1444579..1446546 (+) | 1968 | WP_059257397.1 | peptide ABC transporter substrate-binding protein | Regulator |
| AVT04_RS07745 (AVT04_07745) | amiC | 1446608..1448101 (+) | 1494 | WP_011227407.1 | ABC transporter permease | Regulator |
| AVT04_RS07750 (AVT04_07750) | amiD | 1448101..1449027 (+) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| AVT04_RS07755 (AVT04_07755) | amiE | 1449037..1450122 (+) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| AVT04_RS07760 (AVT04_07760) | amiF | 1450115..1451044 (+) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| AVT04_RS07765 (AVT04_07765) | - | 1451094..1451879 (-) | 786 | WP_002951425.1 | hypothetical protein | - |
| AVT04_RS07770 (AVT04_07770) | - | 1451891..1452589 (-) | 699 | WP_011226301.1 | ABC transporter ATP-binding protein | - |
| AVT04_RS07775 (AVT04_07775) | - | 1452594..1452971 (-) | 378 | WP_011226300.1 | GntR family transcriptional regulator | - |
| AVT04_RS07780 (AVT04_07780) | - | 1453154..1453948 (+) | 795 | WP_059257398.1 | HAD hydrolase family protein | - |
| AVT04_RS07785 (AVT04_07785) | - | 1453941..1454756 (+) | 816 | WP_011227405.1 | Cof-type HAD-IIB family hydrolase | - |
| AVT04_RS07790 (AVT04_07790) | ftsY | 1454770..1456161 (+) | 1392 | WP_011226297.1 | signal recognition particle-docking protein FtsY | - |
| AVT04_RS07795 (AVT04_07795) | gmk | 1456394..1457023 (+) | 630 | WP_011226296.1 | guanylate kinase | - |
| AVT04_RS07800 (AVT04_07800) | rpoZ | 1457045..1457359 (+) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| AVT04_RS07805 (AVT04_07805) | - | 1457501..1459897 (+) | 2397 | WP_011227404.1 | primosomal protein N' | - |
| AVT04_RS07810 (AVT04_07810) | fmt | 1459915..1460850 (+) | 936 | WP_002951411.1 | methionyl-tRNA formyltransferase | - |
| AVT04_RS07815 (AVT04_07815) | rsmB | 1460840..1462162 (+) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| AVT04_RS07820 (AVT04_07820) | - | 1462206..1462943 (+) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| AVT04_RS07825 (AVT04_07825) | stkP/pknB | 1462943..1464814 (+) | 1872 | WP_011226292.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| AVT04_RS11285 | - | 1465451..1465606 (+) | 156 | WP_011226290.1 | ion channel | - |
| AVT04_RS07830 (AVT04_07830) | liaF | 1465872..1466570 (+) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
Sequence
Protein
Download Length: 497 a.a. Molecular weight: 55721.59 Da Isoelectric Point: 10.0618
>NTDB_id=166350 AVT04_RS07745 WP_011227407.1 1446608..1448101(+) (amiC) [Streptococcus thermophilus strain S9]
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAIYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTIFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAIYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTIFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
Nucleotide
Download Length: 1494 bp
>NTDB_id=166350 AVT04_RS07745 WP_011227407.1 1446608..1448101(+) (amiC) [Streptococcus thermophilus strain S9]
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCGAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGCTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTATCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAACTTTGTGAAGATGAACCTTGGTACATCTTACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACAATCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCGAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGCTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTATCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAACTTTGTGAAGATGAACCTTGGTACATCTTACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACAATCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiC | Streptococcus thermophilus LMG 18311 |
99.799 |
100 |
0.998 |
| amiC | Streptococcus thermophilus LMD-9 |
99.396 |
100 |
0.994 |
| amiC | Streptococcus salivarius strain HSISS4 |
97.183 |
100 |
0.972 |