Detailed information NTG0166137

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: A2V17_RS09460
• Genome accession: NZ_CP017090
• Coordinates: 1873621..1874610 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain ISU935 isolate ST5
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1868621..1879610

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2V17_RS09445 (A2V17_09285)	acsA	1869822..1871528 (-)	1707	WP_000862095.1	acetate--CoA ligase	-
A2V17_RS09450 (A2V17_09290)	-	1871697..1872329 (+)	633	WP_001016004.1	hypothetical protein	-
A2V17_RS09455 (A2V17_09295)	-	1872354..1873523 (+)	1170	WP_001184015.1	acetoin utilization protein AcuC	-
A2V17_RS09460 (A2V17_09300)	ccpA	1873621..1874610 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
A2V17_RS09465 (A2V17_09305)	-	1874683..1874796 (-)	114	WP_001788994.1	hypothetical protein	-
A2V17_RS09470 (A2V17_09310)	-	1875150..1876241 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
A2V17_RS09475 (A2V17_09315)	-	1876696..1876779 (-)	84	WP_031761406.1	hypothetical protein	-
A2V17_RS09480 (A2V17_09320)	-	1876935..1878293 (-)	1359	WP_000193903.1	hypothetical protein	-
A2V17_RS09485 (A2V17_09325)	-	1878367..1878858 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=166137 A2V17_RS09460 WP_000219066.1 1873621..1874610(-) (ccpA) [Staphylococcus aureus strain ISU935 isolate ST5]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=166137 A2V17_RS09460 WP_000219066.1 1873621..1874610(-) (ccpA) [Staphylococcus aureus strain ISU935 isolate ST5]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCTAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462