Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AWC37_RS07395 Genome accession   NZ_CP013922
Coordinates   1494584..1495213 (-) Length   209 a.a.
NCBI ID   WP_017723494.1    Uniprot ID   -
Organism   Staphylococcus xylosus strain S170     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1489584..1500213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AWC37_RS07365 (AWC37_07310) - 1489856..1490377 (-) 522 WP_029378985.1 acyl-CoA thioesterase -
  AWC37_RS07370 (AWC37_07315) - 1490465..1491703 (-) 1239 WP_038678839.1 aminopeptidase -
  AWC37_RS07375 (AWC37_07320) - 1491721..1491924 (-) 204 WP_017723498.1 DUF1128 family protein -
  AWC37_RS07380 (AWC37_07325) - 1492059..1492523 (+) 465 WP_029378983.1 low molecular weight protein-tyrosine-phosphatase -
  AWC37_RS07385 (AWC37_07330) - 1492530..1492814 (+) 285 WP_029378982.1 hypothetical protein -
  AWC37_RS07390 (AWC37_07335) - 1493170..1494315 (+) 1146 WP_058625640.1 YihY/virulence factor BrkB family protein -
  AWC37_RS07395 (AWC37_07340) vraR 1494584..1495213 (-) 630 WP_017723494.1 response regulator transcription factor Regulator
  AWC37_RS07400 (AWC37_07345) vraS 1495203..1496246 (-) 1044 WP_029378980.1 sensor histidine kinase Regulator
  AWC37_RS07405 (AWC37_07350) liaF 1496243..1496944 (-) 702 WP_029378979.1 cell wall-active antibiotics response protein LiaF -
  AWC37_RS07410 (AWC37_07355) - 1496961..1497347 (-) 387 WP_029378978.1 hypothetical protein -
  AWC37_RS07415 (AWC37_07360) map 1497452..1498204 (-) 753 WP_029378977.1 type I methionyl aminopeptidase -
  AWC37_RS07420 (AWC37_07365) - 1498381..1499367 (+) 987 WP_038678842.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23734.27 Da        Isoelectric Point: 4.7778

>NTDB_id=166127 AWC37_RS07395 WP_017723494.1 1494584..1495213(-) (vraR) [Staphylococcus xylosus strain S170]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGKEAIEKAHQLNPDLILMDLLMDDMDGVEATEQVKKDLPHMKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=166127 AWC37_RS07395 WP_017723494.1 1494584..1495213(-) (vraR) [Staphylococcus xylosus strain S170]
ATGCCGATTAAAGTTTTATTTGTGGATGACCATGAAATGGTCCGAATTGGAATATCTAGCTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGGAAATCGGGAAAGGAAGCAATTGAAAAAGCTCACCAATTGAATCCTGATTTAATATTAA
TGGATTTACTAATGGATGATATGGACGGTGTTGAAGCAACCGAACAAGTAAAAAAAGATTTACCTCATATGAAAGTAGTC
ATGCTTACGAGTTATATAGAAGATAACGAAGTATACCGTGCACTTGATTCTGGTGTGGATAGCTACATTTTAAAAACAAC
GAGTGCTAGTGATATTGCAGAGGCAATAAGAAAAACCTATAATAATGAGTCGGTTTTTGAAGCAGAAGTTTTAGTTAAGA
TGAGAAATAGAATGAAGCAACGTGCAGAATTATATGAAATGTTAACAGAACGTGAGATGGAAATCTTATTATTAATAGCA
AAAGGCTACTCAAACCAAGAAATAGCAAGCGCCTCACATATAACAATTAAAACTGTTAAAACACATGTAAGTAATATTTT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCTGTTATTTACGCTTTTCAACATAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment