Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   BEN15_RS06565 Genome accession   NZ_CP016877
Coordinates   1228053..1228793 (+) Length   246 a.a.
NCBI ID   WP_065973040.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain KLDS 3.1003     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1223053..1233793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BEN15_RS06530 (BEN15_06525) - 1223360..1223587 (+) 228 WP_012775533.1 DUF5965 family protein -
  BEN15_RS06535 (BEN15_06530) - 1223584..1223973 (+) 390 WP_024408868.1 DUF5945 family protein -
  BEN15_RS06540 (BEN15_06535) - 1224023..1224319 (+) 297 WP_044682494.1 hypothetical protein -
  BEN15_RS06545 (BEN15_06540) - 1224583..1224945 (+) 363 WP_065973038.1 SAG1252 family conjugative relaxosome accessory protein -
  BEN15_RS06550 (BEN15_06545) - 1224948..1225313 (+) 366 WP_039671039.1 plasmid mobilization protein -
  BEN15_RS06555 (BEN15_06550) - 1225300..1227183 (+) 1884 WP_065973039.1 SAG1250 family conjugative relaxase -
  BEN15_RS06560 (BEN15_06555) - 1227710..1228051 (+) 342 WP_024404826.1 LytR/AlgR family response regulator transcription factor -
  BEN15_RS06565 (BEN15_06560) comE/blpR 1228053..1228793 (+) 741 WP_065973040.1 response regulator transcription factor Regulator
  BEN15_RS06570 (BEN15_06565) - 1228804..1230144 (+) 1341 WP_039671036.1 sensor histidine kinase -
  BEN15_RS11035 - 1230192..1230347 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  BEN15_RS06575 (BEN15_06570) comB 1230446..1231807 (-) 1362 WP_065973041.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28932.29 Da        Isoelectric Point: 7.9472

>NTDB_id=165065 BEN15_RS06565 WP_065973040.1 1228053..1228793(+) (comE/blpR) [Streptococcus thermophilus strain KLDS 3.1003]
MNIFVMEDDFMQQARIEKIITKLLEKHNIVPKKFEISGKPHQLLQAIEEKGVHQLFFLDIEIKEDLLKGLQVAKQIRDID
PYASIVFVTTHSEFMPLSFRYQVSALDYIDKELGVTEFESRIEAALLHTYNRDKSAVSDDSFYFKSKYAQVQYPFNEVYY
IETSPRPHRVILYTKTDRMEFTASLSDILKQDKRLVQCHRSFAINPRNVVKVDRNEKQIYFPNGATCFISRQKLESTLAV
IDRLHR

Nucleotide


Download         Length: 741 bp        

>NTDB_id=165065 BEN15_RS06565 WP_065973040.1 1228053..1228793(+) (comE/blpR) [Streptococcus thermophilus strain KLDS 3.1003]
ATGAATATCTTTGTAATGGAAGATGATTTTATGCAACAAGCGAGAATTGAGAAGATTATTACTAAGCTGTTAGAAAAGCA
CAACATCGTTCCGAAAAAATTTGAAATTTCAGGAAAACCTCATCAGCTACTTCAAGCAATAGAAGAAAAAGGGGTACATC
AGCTATTCTTTTTAGATATTGAGATTAAGGAAGACCTACTAAAAGGACTTCAAGTTGCTAAACAAATTAGAGATATTGAC
CCTTATGCTAGTATTGTTTTTGTGACAACACACTCCGAGTTTATGCCCTTATCTTTCAGGTACCAGGTGTCTGCCTTGGA
CTATATTGACAAAGAGCTTGGAGTTACCGAATTTGAATCGCGAATAGAAGCAGCTTTACTTCATACTTACAATAGAGATA
AGAGCGCCGTATCGGATGATTCATTCTATTTTAAGTCTAAATATGCTCAAGTACAATACCCATTCAATGAAGTGTACTAC
ATCGAGACTTCTCCCCGCCCTCATCGTGTTATCCTTTATACCAAGACAGACCGAATGGAGTTCACAGCAAGTTTGTCAGA
CATTTTGAAACAAGATAAACGACTTGTACAATGTCATCGTTCGTTTGCAATCAATCCGAGGAATGTTGTTAAAGTGGATA
GAAATGAAAAACAGATCTACTTTCCTAATGGAGCCACCTGTTTTATTTCAAGGCAAAAGCTAGAATCAACTTTAGCTGTT
ATTGATAGACTGCATAGATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.719

98.374

0.528
  comE/comE1 Streptococcus equinus JB1

40.586

97.154

0.394

Multiple sequence alignment