Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   BEN15_RS02235 Genome accession   NZ_CP016877
Coordinates   439317..439610 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain KLDS 3.1003     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 434317..444610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BEN15_RS02195 (BEN15_02200) - 434719..435162 (-) 444 WP_011681680.1 hypothetical protein -
  BEN15_RS11515 (BEN15_02205) - 435236..435661 (-) 426 WP_014608739.1 CPBP family intramembrane glutamic endopeptidase -
  BEN15_RS11520 (BEN15_02210) - 435618..435893 (-) 276 WP_011681681.1 hypothetical protein -
  BEN15_RS02210 (BEN15_02215) - 435905..436102 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  BEN15_RS02215 (BEN15_02220) - 436351..437544 (-) 1194 WP_014608740.1 acetate kinase -
  BEN15_RS02220 (BEN15_02225) comGH 437600..438556 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  BEN15_RS02225 (BEN15_02230) comGG 438601..438918 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  BEN15_RS02230 (BEN15_02235) comGF 438896..439333 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  BEN15_RS02235 (BEN15_02240) comGE 439317..439610 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  BEN15_RS02240 (BEN15_02245) comGD 439582..440010 (-) 429 WP_257608452.1 competence type IV pilus minor pilin ComGD Machinery gene
  BEN15_RS02245 (BEN15_02250) comGC 439970..440296 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  BEN15_RS02250 (BEN15_02255) comGB 440293..441393 (-) 1101 WP_142350125.1 competence type IV pilus assembly protein ComGB Machinery gene
  BEN15_RS02255 (BEN15_02260) comGA/cglA/cilD 441275..442216 (-) 942 WP_065972616.1 competence type IV pilus ATPase ComGA Machinery gene
  BEN15_RS02260 (BEN15_02265) - 442296..442658 (-) 363 WP_014622006.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=165017 BEN15_RS02235 WP_011226625.1 439317..439610(-) (comGE) [Streptococcus thermophilus strain KLDS 3.1003]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=165017 BEN15_RS02235 WP_011226625.1 439317..439610(-) (comGE) [Streptococcus thermophilus strain KLDS 3.1003]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361

Multiple sequence alignment