Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   MGAS11027_RS03860 Genome accession   NZ_CP013838
Coordinates   759771..761000 (+) Length   409 a.a.
NCBI ID   WP_031488352.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS11027     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 754771..766000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS11027_RS03840 (MGAS11027_0786) - 755387..756664 (-) 1278 WP_010922170.1 hydroxymethylglutaryl-CoA reductase, degradative -
  MGAS11027_RS03845 (MGAS11027_0787) - 756651..757826 (-) 1176 WP_031488354.1 hydroxymethylglutaryl-CoA synthase -
  MGAS11027_RS03850 (MGAS11027_0788) - 758035..758874 (+) 840 WP_011017679.1 thymidylate synthase -
  MGAS11027_RS03855 (MGAS11027_0789) - 758954..759451 (+) 498 WP_031488353.1 dihydrofolate reductase -
  MGAS11027_RS09320 (MGAS11027_0790) - 759471..759641 (+) 171 WP_002990165.1 hypothetical protein -
  MGAS11027_RS03860 (MGAS11027_0791) clpX 759771..761000 (+) 1230 WP_031488352.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  MGAS11027_RS03865 (MGAS11027_0792) yihA 761010..761609 (+) 600 WP_002990160.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  MGAS11027_RS03870 (MGAS11027_0793) - 761757..762500 (+) 744 WP_002984942.1 hypothetical protein -
  MGAS11027_RS03875 (MGAS11027_0794) - 762558..764657 (-) 2100 WP_031488351.1 AAA family ATPase -
  MGAS11027_RS03880 (MGAS11027_0795) rpiA 765035..765718 (+) 684 WP_002984936.1 ribose-5-phosphate isomerase RpiA -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 44991.48 Da        Isoelectric Point: 4.6184

>NTDB_id=165017 MGAS11027_RS03860 WP_031488352.1 759771..761000(+) (clpX) [Streptococcus pyogenes strain MGAS11027]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIKI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=165017 MGAS11027_RS03860 WP_031488352.1 759771..761000(+) (clpX) [Streptococcus pyogenes strain MGAS11027]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGTCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTTTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTAAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.242

100

0.892
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.603

98.044

0.575

Multiple sequence alignment