Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   BEN15_RS02220 Genome accession   NZ_CP016877
Coordinates   437600..438556 (-) Length   318 a.a.
NCBI ID   WP_011226622.1    Uniprot ID   Q5M2G5
Organism   Streptococcus thermophilus strain KLDS 3.1003     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 432600..443556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BEN15_RS02185 (BEN15_02190) proC 433160..433930 (+) 771 WP_011226616.1 pyrroline-5-carboxylate reductase -
  BEN15_RS02190 (BEN15_02195) - 433960..434622 (-) 663 WP_014727719.1 CPBP family intramembrane glutamic endopeptidase -
  BEN15_RS02195 (BEN15_02200) - 434719..435162 (-) 444 WP_011681680.1 hypothetical protein -
  BEN15_RS11515 (BEN15_02205) - 435236..435661 (-) 426 WP_014608739.1 CPBP family intramembrane glutamic endopeptidase -
  BEN15_RS11520 (BEN15_02210) - 435618..435893 (-) 276 WP_011681681.1 hypothetical protein -
  BEN15_RS02210 (BEN15_02215) - 435905..436102 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  BEN15_RS02215 (BEN15_02220) - 436351..437544 (-) 1194 WP_014608740.1 acetate kinase -
  BEN15_RS02220 (BEN15_02225) comGH 437600..438556 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  BEN15_RS02225 (BEN15_02230) comGG 438601..438918 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  BEN15_RS02230 (BEN15_02235) comGF 438896..439333 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  BEN15_RS02235 (BEN15_02240) comGE 439317..439610 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  BEN15_RS02240 (BEN15_02245) comGD 439582..440010 (-) 429 WP_257608452.1 competence type IV pilus minor pilin ComGD Machinery gene
  BEN15_RS02245 (BEN15_02250) comGC 439970..440296 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  BEN15_RS02250 (BEN15_02255) comGB 440293..441393 (-) 1101 WP_142350125.1 competence type IV pilus assembly protein ComGB Machinery gene
  BEN15_RS02255 (BEN15_02260) comGA/cglA/cilD 441275..442216 (-) 942 WP_065972616.1 competence type IV pilus ATPase ComGA Machinery gene
  BEN15_RS02260 (BEN15_02265) - 442296..442658 (-) 363 WP_014622006.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35857.00 Da        Isoelectric Point: 4.7123

>NTDB_id=165014 BEN15_RS02220 WP_011226622.1 437600..438556(-) (comGH) [Streptococcus thermophilus strain KLDS 3.1003]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANELIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTQEKQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIAEVVNSV
AVYIQGDAVRPHILKESNVIISDLPIGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAIFLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTKNAPETFVYPLSDLQNPRILKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=165014 BEN15_RS02220 WP_011226622.1 437600..438556(-) (comGH) [Streptococcus thermophilus strain KLDS 3.1003]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACTATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTTGCTAATGAGCTCATCATCAAAAACAACG
AGAAATTACGGGCGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTTTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATCGGATTTATCATTCTGTACTTGCTCGAAGGTTTGACCCA
GGAAAAACAATTAGATATCTTGGAGATTGGTTCGGGAACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGGATGGAAGTTGATGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGAGGTGGTGAATTCAGTA
GCGGTTTATATCCAAGGGGATGCTGTTCGACCACATATTCTCAAAGAGAGCAACGTTATTATCAGCGATTTACCTATAGG
TTACTACCCTAATGATGAGATTGCGAGTCGTTTCAAGGTGGCAGCAACTGGCGAACACACTTATGCCCATCATCTTCTTA
TGGAGCAATCGCTTAAGTATTTGAAGAAAGATGGTATTGCTATTTTTTTGGCACCAACCAATCTTTTGACAAGCCCTCAA
AGTGATCTGCTTAAGAAGTGGTTATCAGGATATGCTGATATTATTGCTGTTATTACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTAAAAAAACAAACTAAAAATGCTCCTGAGACCTTCGTTTACCCACTTAGCG
ATTTGCAAAATCCAAGGATCCTCAAGGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

68.889

99.057

0.682
  comGH Streptococcus mutans UA140

68.889

99.057

0.682