Detailed information NTG0165009

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: MGAS11027_RS02170
• Genome accession: NZ_CP013838
• Coordinates: 417447..418448 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS11027
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 412447..423448

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS11027_RS02145 (MGAS11027_0443)	-	413121..413804 (-)	684	WP_031488436.1	DUF969 domain-containing protein	-
MGAS11027_RS02150 (MGAS11027_0444)	-	414015..414941 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
MGAS11027_RS02155 (MGAS11027_0445)	-	415086..415463 (-)	378	WP_002985686.1	VOC family protein	-
MGAS11027_RS02160 (MGAS11027_0446)	-	415474..416139 (-)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
MGAS11027_RS02165 (MGAS11027_0447)	-	416188..417273 (-)	1086	WP_031488434.1	aminopeptidase P family protein	-
MGAS11027_RS02170 (MGAS11027_0448)	ccpA	417447..418448 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
MGAS11027_RS02175 (MGAS11027_0449)	-	418579..419577 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
MGAS11027_RS02180 (MGAS11027_0450)	-	419579..420913 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
MGAS11027_RS02185 (MGAS11027_0451)	thrS	421335..423278 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=165009 MGAS11027_RS02170 WP_002985680.1 417447..418448(+) (ccpA) [Streptococcus pyogenes strain MGAS11027]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=165009 MGAS11027_RS02170 WP_002985680.1 417447..418448(+) (ccpA) [Streptococcus pyogenes strain MGAS11027]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559