Detailed information    

insolico Bioinformatically predicted

Overview

Name   rcrQ   Type   Regulator
Locus tag   AU077_RS03750 Genome accession   NZ_CP013688
Coordinates   745556..747328 (+) Length   590 a.a.
NCBI ID   WP_014294716.1    Uniprot ID   A0A380K976
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   regulate competence (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 727778..764302 745556..747328 within 0


Gene organization within MGE regions


Location: 727778..764302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS03665 (AU077_03665) - 728564..728944 (+) 381 WP_039670894.1 DUF1149 family protein -
  AU077_RS03670 (AU077_03670) - 728944..729792 (+) 849 WP_058621575.1 DegV family protein -
  AU077_RS03675 (AU077_03675) dapB 729812..730579 (+) 768 WP_014294731.1 4-hydroxy-tetrahydrodipicolinate reductase -
  AU077_RS03680 (AU077_03680) - 730576..731781 (+) 1206 WP_039670892.1 CCA tRNA nucleotidyltransferase -
  AU077_RS03685 (AU077_03685) - 731778..733649 (+) 1872 WP_014294729.1 ABC-F family ATP-binding cassette domain-containing protein -
  AU077_RS03690 (AU077_03690) - 733727..735466 (+) 1740 WP_014294728.1 ABC transporter ATP-binding protein -
  AU077_RS03695 (AU077_03695) - 735469..737235 (+) 1767 WP_014294727.1 ABC transporter ATP-binding protein -
  AU077_RS03700 (AU077_03700) queC 737480..738139 (+) 660 WP_058621576.1 7-cyano-7-deazaguanine synthase QueC -
  AU077_RS03705 (AU077_03705) queD 738132..738578 (+) 447 WP_014294725.1 6-carboxytetrahydropterin synthase QueD -
  AU077_RS03710 (AU077_03710) queE 738571..739284 (+) 714 WP_014294724.1 7-carboxy-7-deazaguanine synthase QueE -
  AU077_RS03715 (AU077_03715) queF 739297..739788 (+) 492 WP_014294723.1 preQ(1) synthase -
  AU077_RS03720 (AU077_03720) - 739844..740341 (-) 498 WP_014294722.1 DUF308 domain-containing protein -
  AU077_RS03725 (AU077_03725) gdhA 740587..741939 (+) 1353 WP_058621577.1 NADP-specific glutamate dehydrogenase -
  AU077_RS03730 (AU077_03730) - 742216..742725 (+) 510 WP_058621578.1 GNAT family N-acetyltransferase -
  AU077_RS03735 (AU077_03735) - 742722..743132 (+) 411 WP_014294719.1 peptide deformylase -
  AU077_RS03740 (AU077_03740) rcrR 743308..743748 (+) 441 WP_058622012.1 MarR family winged helix-turn-helix transcriptional regulator Regulator
  AU077_RS03745 (AU077_03745) rcrP 743752..745566 (+) 1815 WP_058621579.1 ABC transporter ATP-binding protein Regulator
  AU077_RS03750 (AU077_03750) rcrQ 745556..747328 (+) 1773 WP_014294716.1 ABC transporter ATP-binding protein Regulator
  AU077_RS03755 (AU077_03755) - 747594..748570 (+) 977 Protein_763 zinc-binding dehydrogenase -
  AU077_RS03760 (AU077_03760) - 748560..749012 (+) 453 WP_058621580.1 MarR family winged helix-turn-helix transcriptional regulator -
  AU077_RS03765 (AU077_03765) - 749002..749637 (+) 636 WP_058621581.1 ABC transporter permease -
  AU077_RS03770 (AU077_03770) - 749627..750547 (+) 921 WP_058621582.1 glycine betaine ABC transporter substrate-binding protein -
  AU077_RS03775 (AU077_03775) - 750560..751333 (+) 774 WP_058621583.1 ABC transporter ATP-binding protein -
  AU077_RS03780 (AU077_03780) - 751326..751952 (+) 627 WP_014294711.1 ABC transporter permease -
  AU077_RS03785 (AU077_03785) - 752088..752711 (+) 624 WP_014294710.1 GTP pyrophosphokinase -
  AU077_RS03790 (AU077_03790) - 752741..753421 (+) 681 WP_058621584.1 response regulator transcription factor -
  AU077_RS03795 (AU077_03795) - 753430..754659 (+) 1230 WP_058621585.1 sensor histidine kinase -
  AU077_RS03805 (AU077_03805) - 755313..755912 (+) 600 WP_082306730.1 restriction endonuclease subunit S -
  AU077_RS03810 (AU077_03810) - 755905..758991 (+) 3087 WP_196479521.1 type I restriction endonuclease subunit R -
  AU077_RS03815 (AU077_03815) - 758995..759858 (+) 864 WP_058621587.1 KilA-N domain-containing protein -
  AU077_RS03820 (AU077_03820) - 759851..761053 (+) 1203 WP_058621588.1 restriction endonuclease subunit S -
  AU077_RS03825 (AU077_03825) - 761149..762804 (+) 1656 WP_058621589.1 type I restriction-modification system subunit M -
  AU077_RS11030 - 763105..763383 (+) 279 Protein_777 hypothetical protein -
  AU077_RS03830 (AU077_03830) - 763463..764302 (-) 840 WP_014294703.1 aldo/keto reductase -

Sequence

Protein


Download         Length: 590 a.a.        Molecular weight: 65316.51 Da        Isoelectric Point: 5.3523

>NTDB_id=164045 AU077_RS03750 WP_014294716.1 745556..747328(+) (rcrQ) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MENKKKTSFYGRMKPYIRGLQLPFLLAVIGAIVSATITVIGPDKLKEITNIITKGLTPTATGMIPGIDLDKVGKIALTLA
ILYVISAVVGYIQSFTVATIVQRFSQRLRKAIQTKINKVPLSYFDSHSQGDTLSRVTNDVDLLGQSLNQSLGTLVTSTML
LIGSIFMMFHSNVSMALTAIGSVLIGFVLVMVIMGSSQPLFKRQQNNLAAINGYVEEIYSGHNVVTSYNAVGETSETFKK
LNTNLYKSMWQSQFLSGIMMPLMIFVGNFGYVMVCVVGAIKVINGDITMGDVVAFMTYVRIFSQPLSQIAQAFTQMQSAT
AAMSRVFEFLEEDEMEDESDKERQLSDVNGEVTFDNVFFGYSKDKTIIHDFSAVAKPGQKVAIVGPTGAGKTTIVNLLMR
FYEIDKGQITIDSVDTRLMTREEVHDQFSMVLQDTWLFEGTIKENLIYNQENITDEQVIAAAKAVGVHHFIMTLPKGYDT
YLDDSVTLSIGQKQLLTIARALLKDSPLLILDEATSSVDTRTEELIQKAMDKLMEGRTSFVIAHRLSTIRNADLILVMKD
GNIIEQGNHDDLMQQGGFYADLYNSQFEAA

Nucleotide


Download         Length: 1773 bp        

>NTDB_id=164045 AU077_RS03750 WP_014294716.1 745556..747328(+) (rcrQ) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGGAAAATAAGAAAAAAACATCTTTCTATGGCAGAATGAAGCCCTATATTAGAGGTCTCCAGCTTCCATTTCTTCTTGC
AGTGATTGGAGCAATTGTTTCTGCGACGATTACGGTTATTGGACCTGATAAATTAAAAGAAATCACCAATATAATCACCA
AAGGTTTGACACCAACGGCGACTGGTATGATTCCAGGAATCGACTTGGATAAAGTTGGTAAAATTGCATTAACTTTGGCA
ATTTTATACGTTATTTCAGCAGTAGTTGGTTATATTCAAAGCTTTACTGTAGCGACTATCGTTCAACGTTTTTCACAACG
TTTACGTAAAGCTATTCAGACCAAAATTAACAAGGTTCCATTGAGTTACTTTGATAGTCATTCACAAGGAGATACCCTTT
CTCGTGTGACAAATGACGTTGACTTGCTTGGTCAATCGCTTAACCAAAGTTTGGGAACTTTAGTGACATCAACCATGTTA
TTGATTGGTTCAATTTTCATGATGTTCCATTCAAATGTCAGCATGGCTTTAACAGCGATTGGGTCTGTTCTGATTGGTTT
TGTTTTGGTTATGGTTATCATGGGCTCATCACAACCATTGTTCAAACGCCAACAAAATAACTTGGCTGCGATTAACGGTT
ATGTTGAAGAAATTTACTCTGGTCATAATGTGGTAACAAGTTATAACGCTGTTGGTGAAACAAGCGAAACCTTTAAAAAA
TTAAACACCAATCTTTATAAATCAATGTGGCAATCACAGTTCTTGTCAGGTATTATGATGCCGCTTATGATTTTCGTTGG
GAACTTTGGTTATGTTATGGTCTGTGTGGTTGGTGCTATTAAAGTTATCAATGGTGATATTACCATGGGTGATGTGGTTG
CCTTTATGACTTATGTTCGTATCTTCTCACAACCATTGTCACAAATTGCGCAAGCTTTCACACAAATGCAATCAGCAACA
GCTGCCATGAGTCGTGTCTTTGAATTCCTTGAAGAAGATGAAATGGAAGACGAGTCTGACAAGGAACGTCAACTTAGTGA
TGTTAATGGTGAAGTTACCTTTGATAATGTTTTCTTTGGTTATTCTAAGGATAAAACAATTATCCATGATTTCTCCGCTG
TAGCGAAACCTGGTCAGAAAGTTGCCATTGTTGGACCAACAGGTGCTGGTAAAACAACCATTGTTAACCTGCTCATGAGA
TTCTATGAAATCGATAAAGGTCAAATCACTATTGATAGTGTGGATACACGTTTGATGACACGTGAAGAAGTGCATGACCA
ATTCTCAATGGTGCTTCAAGATACGTGGTTGTTTGAAGGAACAATCAAAGAAAACTTGATTTACAATCAAGAAAATATTA
CAGATGAACAAGTTATTGCAGCGGCTAAGGCTGTTGGTGTTCATCACTTTATCATGACACTTCCAAAAGGTTATGACACT
TATCTTGATGATTCTGTAACGCTTTCAATTGGTCAAAAACAACTCTTGACGATTGCGCGTGCTCTTTTGAAAGATTCACC
GCTCCTTATTTTGGATGAAGCAACGTCATCAGTTGATACACGTACTGAAGAATTGATTCAAAAAGCCATGGATAAATTGA
TGGAAGGTCGTACATCATTTGTTATCGCTCACCGTTTGTCAACGATTAGAAACGCTGACCTTATCCTTGTGATGAAAGAT
GGTAACATCATCGAACAAGGCAATCACGATGATTTGATGCAACAAGGTGGCTTCTATGCTGACCTTTACAATTCACAATT
TGAAGCAGCTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(370-516)

ABC transporter transmembrane region (ABC_membrane)

(25-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380K976

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rcrQ Streptococcus mutans UA159

73.595

99.492

0.732

Multiple sequence alignment