Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   A6L42_RS10270 Genome accession   NZ_CP016671
Coordinates   1955744..1956193 (+) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   Q9JXJ2
Organism   Neisseria meningitidis strain M22783     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1950744..1961193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L42_RS14410 comE 1955192..1955656 (+) 465 WP_164967097.1 helix-hairpin-helix domain-containing protein Machinery gene
  A6L42_RS10270 (A6L42_10270) comP 1955744..1956193 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  A6L42_RS14885 (A6L42_10275) - 1956283..1956623 (-) 341 Protein_1898 5'-nucleotidase -
  A6L42_RS10280 (A6L42_10280) - 1956735..1956947 (-) 213 WP_002224145.1 SWIM zinc finger family protein -
  A6L42_RS10285 (A6L42_10285) - 1957179..1957652 (+) 474 Protein_1900 transposase -
  A6L42_RS10305 (A6L42_10305) - 1958854..1960311 (-) 1458 WP_002258745.1 VWA domain-containing protein -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=162920 A6L42_RS10270 WP_002214937.1 1955744..1956193(+) (comP) [Neisseria meningitidis strain M22783]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=162920 A6L42_RS10270 WP_002214937.1 1955744..1956193(+) (comP) [Neisseria meningitidis strain M22783]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterProScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9JXJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49