Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BB344_RS20585 Genome accession   NZ_CP016497
Coordinates   4218280..4218912 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain UPEC 26-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4213280..4223912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BB344_RS20560 (BB344_20560) yhfG 4213412..4213579 (+) 168 WP_000736858.1 YhfG family protein -
  BB344_RS20565 (BB344_20565) fic 4213569..4214171 (+) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  BB344_RS20570 (BB344_20570) pabA 4214203..4214766 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  BB344_RS20575 (BB344_20575) argD 4214852..4216072 (+) 1221 WP_000963800.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BB344_RS20580 (BB344_20580) yhfK 4216139..4218229 (-) 2091 WP_001304921.1 YccS/YhfK family putative transporter -
  BB344_RS20585 (BB344_20585) crp 4218280..4218912 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BB344_RS20595 (BB344_20595) yhfA 4219214..4219618 (+) 405 WP_001148908.1 OsmC family protein -
  BB344_RS20600 (BB344_20600) prkB 4219673..4220542 (-) 870 WP_001274684.1 phosphoribulokinase -
  BB344_RS20605 (BB344_20605) yheU 4220596..4220814 (-) 219 WP_000907085.1 YheU family protein -
  BB344_RS20610 (BB344_20610) yheT 4220808..4221830 (-) 1023 WP_000057387.1 hydrolase -
  BB344_RS20615 (BB344_20615) yheS 4221830..4223743 (-) 1914 WP_000634808.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=160458 BB344_RS20585 WP_000242755.1 4218280..4218912(-) (crp) [Escherichia coli strain UPEC 26-1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=160458 BB344_RS20585 WP_000242755.1 4218280..4218912(-) (crp) [Escherichia coli strain UPEC 26-1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467