Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   NH62_RS15695 Genome accession   NZ_CP012998
Coordinates   2258044..2258676 (+) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae strain 2012Env-9     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2253044..2263676
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NH62_RS15670 (NH62_22037) - 2253109..2255025 (+) 1917 WP_000627681.1 ABC transporter ATP-binding protein -
  NH62_RS15675 (NH62_22038) - 2255026..2255511 (+) 486 WP_001278735.1 TIGR02444 family protein -
  NH62_RS15680 (NH62_22039) - 2255508..2256497 (+) 990 WP_000627575.1 hydrolase -
  NH62_RS15685 (NH62_22040) - 2256626..2256835 (+) 210 WP_000586561.1 YheU family protein -
  NH62_RS15690 (NH62_22041) - 2256932..2257801 (+) 870 WP_001274667.1 phosphoribulokinase -
  NH62_RS15695 (NH62_22042) crp 2258044..2258676 (+) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  NH62_RS15700 (NH62_22043) - 2258755..2259546 (-) 792 WP_000189091.1 DUF1338 domain-containing protein -
  NH62_RS15705 (NH62_22044) astD 2259689..2261146 (-) 1458 WP_000150134.1 succinylglutamate-semialdehyde dehydrogenase -
  NH62_RS15710 (NH62_22045) astA 2261156..2262175 (-) 1020 WP_000962041.1 arginine N-succinyltransferase -
  NH62_RS15715 (NH62_22046) - 2262314..2263525 (-) 1212 WP_000215480.1 aspartate aminotransferase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=159045 NH62_RS15695 WP_000242749.1 2258044..2258676(+) (crp) [Vibrio cholerae strain 2012Env-9]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=159045 NH62_RS15695 WP_000242749.1 2258044..2258676(+) (crp) [Vibrio cholerae strain 2012Env-9]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAGTTAAT
CCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGACGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTCAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment