Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   FORC23_RS10305 Genome accession   NZ_CP012950
Coordinates   2225215..2227473 (-) Length   752 a.a.
NCBI ID   WP_070225890.1    Uniprot ID   -
Organism   Vibrio parahaemolyticus strain FORC_023 isolate 378     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2205563..2230151 2225215..2227473 within 0


Gene organization within MGE regions


Location: 2205563..2230151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC23_RS10230 (FORC23_1911) - 2205563..2206333 (-) 771 WP_005456207.1 ABC transporter ATP-binding protein -
  FORC23_RS10235 (FORC23_1912) - 2206568..2208028 (-) 1461 WP_070225886.1 flagellar sheath protein A -
  FORC23_RS10240 (FORC23_1913) - 2208485..2210032 (+) 1548 WP_005456280.1 DUF3360 family protein -
  FORC23_RS10245 (FORC23_1914) pflB 2210339..2212615 (+) 2277 WP_005456189.1 formate C-acetyltransferase -
  FORC23_RS10250 (FORC23_1915) - 2212768..2213745 (+) 978 WP_070225887.1 lipid A deacylase LpxR family protein -
  FORC23_RS10255 (FORC23_1916) pflA 2213892..2214632 (+) 741 WP_070225888.1 pyruvate formate lyase 1-activating protein -
  FORC23_RS10260 (FORC23_1917) - 2214793..2215461 (+) 669 WP_021449337.1 energy-coupling factor ABC transporter permease -
  FORC23_RS10265 (FORC23_1918) - 2215616..2216116 (+) 501 WP_005456271.1 YfbU family protein -
  FORC23_RS10270 (FORC23_1919) - 2216605..2218539 (+) 1935 WP_005456210.1 PrkA family serine protein kinase -
  FORC23_RS10275 (FORC23_1920) - 2218587..2219858 (+) 1272 WP_005481863.1 YeaH/YhbH family protein -
  FORC23_RS10280 (FORC23_1921) - 2219870..2221429 (+) 1560 WP_005456192.1 SpoVR family protein -
  FORC23_RS10285 (FORC23_1922) kdsB 2221507..2222262 (-) 756 WP_025540306.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  FORC23_RS10290 (FORC23_1923) - 2222262..2222441 (-) 180 WP_005378451.1 Trm112 family protein -
  FORC23_RS10295 (FORC23_1924) lpxK 2222422..2223429 (-) 1008 WP_070225889.1 tetraacyldisaccharide 4'-kinase -
  FORC23_RS10300 (FORC23_1925) msbA 2223435..2225183 (-) 1749 WP_015296464.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  FORC23_RS10305 (FORC23_1926) comEC 2225215..2227473 (-) 2259 WP_070225890.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FORC23_RS10310 (FORC23_1927) - 2227482..2227991 (+) 510 WP_005456245.1 DUF2062 domain-containing protein -
  FORC23_RS10315 (FORC23_1928) lolE 2228197..2229441 (-) 1245 WP_015296461.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  FORC23_RS10320 (FORC23_1929) lolD 2229444..2230151 (-) 708 WP_005456257.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 84753.35 Da        Isoelectric Point: 9.5661

>NTDB_id=158485 FORC23_RS10305 WP_070225890.1 2225215..2227473(-) (comEC) [Vibrio parahaemolyticus strain FORC_023 isolate 378]
MTLLEKSWTLALFVASVISSAWWPTMPDWRWLLLGIITTGSIIKLRRGLISIGVIVGFMVVIVHGNIMEYQRQALFQAGE
NSTIIGRVDSSFTQISHGYEGVIAIKQVNSHTLLPFLKPKVRLITPFPLAVNSEFTTNVLIKPIIGLRNEAGFDAEKQSM
GSGVVARAVVTKDSYWVIRTSSSWREAIIQTVERDIFRLEHFALIKALAFADRTGLTKEDWQSLRDSGLLHLVSISGLHI
GMALTFGLALGGLIRLAMPRYWFLPSVSGLAFAIVYAWLADFSLPTTRAVSVCIIYLALKYWLVHWSPWRVLLLAVALQL
FFQPFASFSLSFWLSYLSVGAVLFAVNTVQDSKEGRLGKLRILLLTQLILSLLIVPISGYFFSGFSWSSLVYNLVFIPWF
GFVVVPIMFAALIASLLFPMLATVLWYLLDVFLVPLSWSVRYAIGTWQPISAEWTFVIAVVSVVLVLRHVMPRYVWMFVC
VIVVMTGLFPKQYNQTWRIDVLDVGHGLAVLVEKEGRVLLYDTGKAWQNGSIAEQVITPVLHRRGYSSVDTMILSHADND
HAGGRKVIEQYFSPKHKLSSQSFLHYQPCIAAEKWKWQGLNMEVLWPPKPVVRAYNPHSCVISLEDPSSGLKMLFTGDIE
AISEWILLREPEKLRSDVMLVPHHGSKSSSNLKFINAVEPSLAIASTAKLNQWGMPAPEVVQAYTDSGVSWLDTGSDGQI
TILLDGNNWRFESKRRETIEPWYRQMLRNRVE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=158485 FORC23_RS10305 WP_070225890.1 2225215..2227473(-) (comEC) [Vibrio parahaemolyticus strain FORC_023 isolate 378]
ATGACTCTCTTAGAAAAAAGTTGGACCTTGGCGTTATTTGTCGCGAGCGTAATTTCGTCTGCATGGTGGCCGACGATGCC
GGATTGGCGTTGGTTGCTGCTGGGAATAATTACCACTGGCTCAATAATTAAATTACGTCGAGGCTTAATTAGCATAGGCG
TAATTGTGGGCTTTATGGTTGTCATCGTTCACGGCAATATTATGGAGTATCAGAGACAAGCCCTTTTTCAAGCAGGTGAG
AATAGTACCATAATTGGTAGAGTTGACAGCTCTTTTACGCAAATAAGTCACGGATATGAAGGTGTCATAGCGATAAAACA
AGTGAATTCTCACACTCTGTTACCTTTTCTTAAACCTAAAGTCCGCCTTATAACGCCATTCCCACTAGCTGTTAACAGTG
AGTTTACGACTAACGTTTTGATTAAGCCCATTATCGGCCTCAGAAATGAAGCGGGTTTCGACGCAGAAAAGCAGTCAATG
GGAAGTGGTGTTGTTGCAAGGGCGGTCGTAACTAAAGATTCATACTGGGTCATTCGTACTTCTTCGTCTTGGCGCGAAGC
TATTATTCAAACTGTTGAGCGTGATATTTTTCGCCTTGAGCATTTTGCTCTAATTAAAGCACTGGCTTTTGCTGATCGCA
CTGGGCTTACCAAAGAGGATTGGCAGTCTCTGCGTGACAGCGGACTACTGCATCTTGTATCAATTTCTGGTCTACACATT
GGGATGGCATTGACGTTTGGGCTCGCCCTTGGTGGGCTTATTCGGCTTGCTATGCCGCGATATTGGTTTCTGCCATCAGT
GAGTGGGTTGGCGTTTGCCATTGTTTACGCTTGGCTTGCTGATTTTTCTTTGCCGACGACCCGAGCCGTTTCTGTTTGTA
TCATCTATCTTGCTTTGAAGTATTGGCTTGTTCATTGGAGTCCATGGCGCGTACTGTTATTGGCTGTGGCGTTGCAACTT
TTCTTCCAACCTTTTGCTTCTTTTAGTTTGAGTTTTTGGCTGTCTTATTTATCCGTTGGTGCCGTTTTGTTTGCGGTTAA
CACAGTGCAAGACTCGAAGGAAGGTCGTTTGGGAAAGTTGCGGATACTTCTGTTGACTCAACTGATACTGAGCTTATTGA
TTGTCCCGATCAGTGGCTATTTTTTCTCTGGATTTAGCTGGTCTTCTTTAGTCTACAATTTGGTTTTCATTCCTTGGTTT
GGCTTTGTTGTCGTTCCAATCATGTTTGCTGCTTTAATCGCGTCATTGCTCTTTCCTATGTTGGCGACGGTTCTATGGTA
TTTGCTTGACGTATTCCTTGTGCCACTAAGTTGGTCGGTTCGATATGCCATAGGAACTTGGCAACCCATTAGTGCCGAGT
GGACATTTGTTATTGCTGTAGTGAGTGTCGTGCTCGTTTTAAGACATGTTATGCCTCGTTACGTTTGGATGTTTGTCTGT
GTAATTGTTGTGATGACCGGGTTGTTTCCTAAGCAATATAACCAAACTTGGCGTATTGATGTACTTGATGTCGGGCATGG
GCTGGCGGTACTGGTTGAAAAAGAGGGGAGAGTTTTACTCTATGATACGGGCAAGGCTTGGCAAAACGGCAGTATAGCTG
AGCAAGTGATTACGCCAGTACTGCACCGCAGAGGTTACTCAAGTGTCGATACGATGATTTTAAGTCATGCCGATAATGAC
CATGCTGGCGGCCGAAAAGTGATAGAGCAGTACTTTTCACCTAAACACAAACTAAGCAGCCAGAGCTTTTTACATTATCA
GCCTTGTATTGCTGCTGAGAAATGGAAGTGGCAAGGGTTGAACATGGAGGTACTTTGGCCTCCTAAACCTGTTGTACGTG
CATACAACCCCCACTCTTGTGTCATCAGTCTGGAAGACCCTAGTTCAGGTCTTAAAATGTTGTTCACTGGTGATATCGAA
GCCATCAGCGAATGGATACTGCTTCGAGAGCCAGAAAAGCTGCGCAGTGATGTAATGCTAGTGCCGCATCATGGAAGCAA
AAGCTCTTCTAACCTTAAGTTTATCAATGCTGTTGAGCCTAGCTTGGCTATTGCTTCAACGGCAAAACTAAACCAGTGGG
GAATGCCCGCACCTGAAGTCGTTCAAGCCTATACCGACAGTGGTGTTAGTTGGTTAGACACTGGAAGTGATGGCCAAATA
ACAATCTTACTTGATGGCAATAACTGGCGTTTTGAAAGTAAACGTCGTGAGACAATTGAGCCTTGGTATAGGCAGATGCT
GCGTAACCGAGTAGAATAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(504-679)

Competence protein (Competence)

(208-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio parahaemolyticus RIMD 2210633

98.67

100

0.987
  comEC Vibrio campbellii strain DS40M4

66.888

100

0.669
  comEC Vibrio cholerae strain A1552

41.215

100

0.415

Multiple sequence alignment