Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SanJ4206_RS05095 Genome accession   NZ_CP012719
Coordinates   1042495..1043841 (-) Length   448 a.a.
NCBI ID   WP_003024354.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4206     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1037495..1048841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS05075 (SanJ4206_0968) rpsT 1037877..1038128 (+) 252 WP_020999623.1 30S ribosomal protein S20 -
  SanJ4206_RS05080 - 1038193..1038702 (+) 510 WP_003029599.1 DNA topology modulation protein -
  SanJ4206_RS05085 (SanJ4206_0970c) - 1038750..1040363 (-) 1614 WP_003029598.1 M20/M25/M40 family metallo-hydrolase -
  SanJ4206_RS05090 (SanJ4206_0971) - 1040540..1041988 (+) 1449 WP_003029597.1 alpha-amylase -
  SanJ4206_RS05095 (SanJ4206_0972c) ciaH 1042495..1043841 (-) 1347 WP_003024354.1 sensor histidine kinase Regulator
  SanJ4206_RS05100 (SanJ4206_0973c) ciaR 1043831..1044505 (-) 675 WP_003024352.1 response regulator transcription factor Regulator
  SanJ4206_RS05105 (SanJ4206_0974c) - 1044778..1045233 (-) 456 WP_003029592.1 hypothetical protein -
  SanJ4206_RS05110 (SanJ4206_0975c) - 1045619..1046149 (-) 531 WP_003029588.1 alpha/beta hydrolase -
  SanJ4206_RS05115 (SanJ4206_0977) - 1046777..1047025 (+) 249 WP_003029583.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  SanJ4206_RS05120 (SanJ4206_0978) - 1047022..1047318 (+) 297 WP_003024343.1 type II toxin-antitoxin system RelE family toxin -
  SanJ4206_RS05125 (SanJ4206_0979c) - 1047426..1048274 (-) 849 WP_003029580.1 hypothetical protein -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 51038.78 Da        Isoelectric Point: 10.1380

>NTDB_id=156784 SanJ4206_RS05095 WP_003024354.1 1042495..1043841(-) (ciaH) [Streptococcus anginosus strain J4206]
MLNKLKKTWYADDFSYFIRNFGIFTLIFSAMTLIIIQVMRSSLYTTVDNNLKSLSQDSASVINLALARRVGMEQKSDNGE
PKTDTGDKELTDKPNVSANTEVILFDKNYKPIITSNNFLGLNKLSFNSKQLDRIRQVQVKSNYGRQETYRMILFEVKIPN
LETNVKYAAVFINISQLEQTSQNHEQLIVVVMISFWGISLIASVYLARVSVKPLLESIQKQKSFVENASHELRTPLAVLQ
NRLETLFRKPEATIMESSESIASSLDEVRNMKMLTTNLLNLARRDDGIKPEIGDVEPNFFNTTFTNYEMVAAENGKTFRF
DNRIHRMIKTDKTLLKQLMTILFDNALKYTDEDGVIELTISANDRNLFLKVSDNGPGISTADKKKIFDRFYRVDKARTRQ
TGGFGLGLSLAKQITEALKGTITVKDNKPKGTIFEVKIAIRTDNRKKK

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=156784 SanJ4206_RS05095 WP_003024354.1 1042495..1043841(-) (ciaH) [Streptococcus anginosus strain J4206]
ATGCTGAATAAACTAAAAAAAACATGGTATGCGGATGATTTTTCTTATTTCATTCGCAATTTTGGTATTTTTACTCTCAT
TTTCTCAGCCATGACTTTGATTATCATTCAGGTGATGCGCTCAAGCCTTTATACAACGGTTGATAATAACTTGAAAAGTC
TCAGTCAGGATTCTGCTTCTGTCATCAATTTGGCACTCGCTCGGAGAGTGGGGATGGAACAGAAGTCAGACAACGGAGAG
CCTAAAACCGATACGGGTGACAAAGAGCTTACTGATAAACCAAATGTCAGTGCCAATACGGAAGTTATTTTATTTGATAA
GAATTATAAGCCAATCATTACAAGCAATAATTTTCTGGGACTTAATAAACTTTCCTTTAATAGCAAGCAATTGGATCGCA
TTCGGCAAGTCCAGGTTAAAAGCAATTATGGTCGACAAGAAACCTATCGGATGATTTTATTTGAAGTGAAAATCCCAAAT
TTGGAAACCAATGTCAAATATGCAGCGGTCTTTATCAATATCAGTCAGTTGGAACAAACTAGTCAAAATCATGAGCAGCT
GATTGTAGTTGTGATGATTAGTTTCTGGGGAATTTCCTTGATTGCCAGTGTCTATCTGGCTCGGGTTAGTGTTAAACCTT
TGTTGGAGAGTATTCAAAAGCAAAAGAGCTTTGTTGAAAATGCCAGTCATGAGTTGCGCACGCCTCTAGCTGTTTTACAA
AATCGTTTGGAGACTTTGTTTAGAAAACCAGAAGCCACCATTATGGAATCGAGTGAAAGCATCGCTTCTAGTTTAGATGA
AGTGCGAAACATGAAAATGTTGACAACGAACTTACTTAATTTAGCACGGCGTGACGACGGGATTAAACCAGAAATTGGCG
ATGTCGAGCCAAATTTCTTTAATACGACCTTTACCAACTATGAAATGGTTGCCGCAGAAAATGGGAAAACTTTCCGATTT
GACAATAGGATTCACCGCATGATTAAAACAGACAAGACCTTGCTGAAGCAATTAATGACGATTCTGTTTGACAATGCTCT
GAAATATACAGATGAAGACGGTGTGATTGAATTGACAATCTCTGCAAATGATCGAAATTTGTTTTTAAAGGTTTCAGATA
ATGGTCCGGGGATTAGTACGGCAGATAAGAAAAAGATTTTTGATCGTTTTTATCGGGTTGATAAAGCACGGACTCGGCAG
ACAGGTGGTTTTGGTCTAGGCTTGTCGCTTGCAAAGCAAATCACAGAAGCTCTTAAAGGAACTATTACGGTGAAAGATAA
TAAGCCGAAAGGAACTATTTTTGAGGTGAAGATTGCCATTAGAACGGATAATAGAAAGAAAAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(331-438)

His Kinase A (phospho-acceptor) domain (HisKA)

(222-287)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

71.429

100

0.714
  ciaH Streptococcus pneumoniae D39

71.429

100

0.714
  ciaH Streptococcus pneumoniae R6

71.429

100

0.714
  ciaH Streptococcus pneumoniae TIGR4

71.429

100

0.714
  ciaH Streptococcus mutans UA159

56.009

98.438

0.551

Multiple sequence alignment