Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SanJ4206_RS02140 Genome accession   NZ_CP012719
Coordinates   428985..430286 (+) Length   433 a.a.
NCBI ID   WP_003028383.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4206     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 423985..435286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS02115 (SanJ4206_0383) - 424475..424864 (+) 390 WP_003028388.1 hypothetical protein -
  SanJ4206_RS02120 (SanJ4206_0384) - 424940..425500 (+) 561 WP_022525299.1 hypothetical protein -
  SanJ4206_RS02125 (SanJ4206_0385) - 425578..426858 (+) 1281 WP_003028386.1 hypothetical protein -
  SanJ4206_RS02130 (SanJ4206_0386c) cysK 427264..428193 (-) 930 WP_003028385.1 cysteine synthase A -
  SanJ4206_RS02135 (SanJ4206_0387c) - 428293..428928 (-) 636 WP_003028384.1 YigZ family protein -
  SanJ4206_RS02140 (SanJ4206_0388) comFA/cflA 428985..430286 (+) 1302 WP_003028383.1 DEAD/DEAH box helicase Machinery gene
  SanJ4206_RS02145 (SanJ4206_0389) - 430283..430948 (+) 666 WP_003028382.1 ComF family protein -
  SanJ4206_RS02150 (SanJ4206_0390) hpf 431029..431571 (+) 543 WP_003028381.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SanJ4206_RS02155 (SanJ4206_0391) rsmD 431762..432310 (+) 549 WP_176601969.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SanJ4206_RS02160 (SanJ4206_0392) coaD 432300..432797 (+) 498 WP_003028379.1 pantetheine-phosphate adenylyltransferase -
  SanJ4206_RS02165 (SanJ4206_0393) sepM 432778..433833 (+) 1056 WP_003028378.1 SepM family pheromone-processing serine protease Regulator
  SanJ4206_RS02170 (SanJ4206_0394) - 433973..434536 (+) 564 WP_003043206.1 YutD family protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 48876.73 Da        Isoelectric Point: 8.3812

>NTDB_id=156765 SanJ4206_RS02140 WP_003028383.1 428985..430286(+) (comFA/cflA) [Streptococcus anginosus strain J4206]
MTELQDCLGRIFTKSQLSPELQLQAQSLAGMVEEKGKLSCNRCGQAIDKEKQQLPIGAYYCRSCLILGRVRSDEELYYFP
QEEFPKANVLKWQGKLTEFQAKVSQGLVEAVTKRKDSLVHAVTGAGKTEMIYQVVAQVINQGGAVCLASPRIDVCLELYR
RLKVDFTCDISLLHGESEAYSRSPLVIATTHQLLKFYQAFDLLIVDEVDAFPYVDNPMLYHAVHQAVKVEGTKIFLTATS
TDELDKKVAKGELTRLSLPRRFHGNPLIVPQKIWLADFQKYLGQKKLVPKLRQFIQKQRKTSFPLLIFASEIKKGQELAE
ILQSTFPNEKVGFVASTTENRLEIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSMD
RPTGELIFFHDGATMAIEKAIKEIQEMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=156765 SanJ4206_RS02140 WP_003028383.1 428985..430286(+) (comFA/cflA) [Streptococcus anginosus strain J4206]
ATGACGGAATTACAAGATTGCTTAGGTCGTATTTTTACAAAAAGTCAATTGTCACCAGAATTGCAATTGCAAGCACAAAG
CTTAGCTGGAATGGTAGAAGAGAAAGGAAAGTTAAGCTGTAATCGCTGTGGACAAGCCATTGACAAAGAAAAACAGCAAC
TACCAATTGGTGCTTATTATTGTAGGTCTTGCTTGATCTTAGGAAGGGTTAGGAGTGATGAAGAACTATACTATTTTCCA
CAGGAAGAATTTCCCAAAGCGAATGTTTTGAAATGGCAAGGAAAGTTGACAGAATTTCAAGCTAAGGTTTCTCAAGGACT
TGTAGAGGCGGTTACCAAACGCAAAGATAGCTTGGTTCACGCAGTCACAGGAGCCGGAAAGACGGAAATGATCTATCAGG
TGGTGGCACAAGTCATCAATCAAGGTGGAGCCGTCTGCTTGGCTAGCCCCAGAATTGATGTCTGCTTAGAACTTTATCGC
AGACTGAAAGTAGATTTTACTTGCGATATTTCACTCCTGCACGGTGAATCAGAAGCATATTCCCGCAGTCCTCTCGTGAT
TGCTACAACGCATCAGCTTCTCAAATTTTATCAAGCCTTTGATCTTCTTATCGTTGATGAAGTAGATGCCTTTCCTTACG
TGGACAATCCGATGCTTTATCATGCGGTTCATCAGGCAGTTAAAGTAGAGGGAACGAAGATTTTCTTAACAGCAACTTCC
ACAGATGAGTTGGATAAAAAAGTGGCTAAAGGAGAATTAACTCGTTTGAGTCTACCTAGACGTTTTCATGGGAATCCTTT
GATTGTTCCTCAAAAAATTTGGTTGGCAGATTTTCAAAAATATCTTGGTCAAAAGAAGCTAGTTCCTAAGTTAAGACAGT
TTATTCAAAAGCAGAGAAAAACCAGCTTTCCACTTCTTATTTTTGCTTCTGAGATTAAAAAGGGGCAGGAATTAGCAGAG
ATTCTTCAAAGCACTTTTCCTAATGAAAAAGTTGGCTTTGTAGCCTCGACGACTGAAAATCGACTGGAAATTGTAGAGAA
ATTTCGTCAAAAAGAAATCACGATTTTGGTAACAACGACAATTCTAGAACGTGGTGTAACTTTTCCTTGTGTAGATGTTT
TTGTGGTGGAGGCTAACCACCGTTTGTTTAGTCGCAGCGCTCTGGTACAAATCGCTGGACGCGTCGGTCGCAGTATGGAT
CGACCGACAGGCGAGTTAATCTTTTTTCATGACGGTGCGACTATGGCGATAGAAAAAGCGATTAAAGAAATTCAGGAGAT
GAATCAGGAGGCCGGTTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(108-245)

Helicase conserved C-terminal domain (Helicase_C)

(291-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

72.43

98.845

0.716
  comFA/cflA Streptococcus pneumoniae D39

72.43

98.845

0.716
  comFA/cflA Streptococcus pneumoniae R6

72.43

98.845

0.716
  comFA/cflA Streptococcus pneumoniae TIGR4

72.196

98.845

0.714
  comFA/cflA Streptococcus mitis NCTC 12261

72.066

98.383

0.709
  comFA/cflA Streptococcus mitis SK321

71.596

98.383

0.704
  comFA Lactococcus lactis subsp. cremoris KW2

55.779

91.917

0.513
  comFA Latilactobacillus sakei subsp. sakei 23K

40.647

100

0.406
  comFA Bacillus subtilis subsp. subtilis str. 168

39.409

93.764

0.37

Multiple sequence alignment