Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   AN159_RS10835 Genome accession   NZ_CP012694
Coordinates   2075860..2078097 (-) Length   745 a.a.
NCBI ID   WP_069972587.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 331401     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2070860..2083097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AN159_RS10815 (AN159_10830) - 2071032..2071496 (-) 465 WP_069972585.1 transcriptional regulator NrdR -
  AN159_RS10820 (AN159_10835) - 2071525..2072367 (-) 843 WP_002222980.1 class II glutamine amidotransferase -
  AN159_RS10825 (AN159_10840) aroB 2073011..2074090 (-) 1080 WP_002236907.1 3-dehydroquinate synthase -
  AN159_RS10830 (AN159_10845) - 2074170..2074682 (-) 513 WP_069972586.1 shikimate kinase -
  AN159_RS10835 (AN159_10850) pilQ 2075860..2078097 (-) 2238 WP_069972587.1 type IV pilus secretin PilQ Machinery gene
  AN159_RS10840 (AN159_10855) pilP 2078116..2078661 (-) 546 WP_069972588.1 pilus assembly protein PilP Machinery gene
  AN159_RS10845 (AN159_10860) - 2078679..2079326 (-) 648 WP_002214521.1 type 4a pilus biogenesis protein PilO -
  AN159_RS10850 (AN159_10865) pilN 2079327..2079926 (-) 600 WP_050305250.1 PilN domain-containing protein Machinery gene
  AN159_RS10855 (AN159_10870) pilM 2079929..2081044 (-) 1116 WP_002246401.1 type IV pilus biogenesis protein PilM -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 80201.53 Da        Isoelectric Point: 9.9818

>NTDB_id=156619 AN159_RS10835 WP_069972587.1 2075860..2078097(-) (pilQ) [Neisseria meningitidis strain 331401]
MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVL
EYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
SVSEPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAAPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTL
KNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFT
GRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIAPRDELLAK
DKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRK
LIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINLPITAAANSIS
LVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIANGGSSTNTELKKAVLGLTVTPNITP
DGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGK
KPDRRELLIFITPRIMGTAGNSLRY

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=156619 AN159_RS10835 WP_069972587.1 2075860..2078097(-) (pilQ) [Neisseria meningitidis strain 331401]
ATGAATACCAAACTGACAAAAATCATTTCCGGTCTCTTTGTCGCAACCGCCGCCTTTCAGACAGCATCGGCAGGAAACAT
TACAGACATCAAAGTTTCCTCCCTGCCCAACAAACAGAAAATCGTCAAAGTCAGCTTTGACAAAGAGATTGTCAACCCGA
CCGGCTTCGTAACCTCCTCACCGGCCCGCATCGCCTTGGACTTTGAACAAACCGGCATTTCCATGGATCAACAGGTACTC
GAATATGCCGATCCTCTGTTGAGCAAAATCAGTGCCGCACAAAACAGCAGCCGTGCGCGTCTGGTTCTGAATCTGAACAA
ACCGGGCCAATACAATACCGAAGTACGCGGGAACAAAGTTTGGATATTCATTAACGAATCGGACGATACCGTGTCCGCCC
CCGCACGCCCCGCCGTAAAAGCCGCGCCTGCCGCACCGGCAAAACAACAGGCTGCCGCACCGTCTACCAAGTCCGCAGTA
TCCGTATCCGAACCCTTTACCCCGGCAAAACAACAGGCTGCCGCACCGTTTACCGAGTCCGTAGTATCCGTATCCGCACC
GTTCAGCCCGGCAAAACAACAGGCGGCGGCACCAGCAAAACAAACCAATATCGATTTCCGCAAAGACGGCAAAAATGCCG
GCATTATCGAATTGGCGGCATTGGGCTTTGCCGGGCAGCCCGACATCAGCCAACAGCACGACCACATCATCGTTACGCTG
AAAAACCATACCCTGCCGACCACGCTCCAACGCAGTTTGGATGTGGCAGACTTTAAAACACCGGTTCAAAAGGTTACGCT
GAAACGCCTCAATAACGACACCCAGCTGATTATCACAACAGCCGGCAACTGGGAACTCGTCAACAAATCCGCCGCGCCCG
GATACTTTACCTTCCAAGTCCTGCCGAAAAAACAAAACCTCGAGTCAGGCGGCGTGAACAATGCGCCCAAAACCTTCACA
GGCCGGAAAATCTCCCTTGACTTCCAAGATGTCGAAATCCGCACCATCCTGCAGATTTTGGCAAAAGAATCCGGGATGAA
CATTGTTGCCAGCGACTCCGTCAACGGCAAAATGACCCTCTCCCTCAAAGACGTACCTTGGGATCAGGCTTTGGATTTGG
TTATGCAGGCACGCAACCTCGATATGCGCCAACAAGGGAACATCGTCAACATCGCGCCCCGCGACGAGCTGCTTGCCAAA
GACAAAGCCTTCTTACAGGCGGAAAAAGACATTGCCGATCTGGGCGCGCTGTATTCACAAAACTTCCAATTGAAATACAA
AAATGTGGAAGAATTCCGCAGCATCCTGCGTTTGGACAATGCCGACACAACCGGAAACCGCAATACGCTTGTCAGCGGCA
GGGGCAGCGTGCTGATCGATCCCGCCACCAATACCCTGATTGTTACCGATACCCGCAGCGTCATCGAAAAATTCCGCAAA
CTGATTGACGAATTGGACGTACCCGCGCAACAAGTGATGATTGAGGCGCGTATCGTCGAAGCGGCAGACGGCTTCTCGCG
CGATTTGGGCGTTAAATTCGGCGCGACAGGCAAGAAAAAGCTGAAAAATGATACAAGCGCATTCGGCTGGGGGGTAAACT
CCGGCTTCGGCGGCGACGATAAATGGGGGGCCGAAACCAAAATCAACCTGCCGATTACCGCTGCCGCAAACAGCATTTCG
CTGGTGCGCGCGATTTCCTCCGGTGCCTTGAATTTGGAATTGTCCGCATCCGAATCGCTTTCAAAAACCAAAACGCTTGC
CAATCCGCGCGTGCTGACCCAAAACCGCAAAGAGGCCAAAATCGAATCTGGTTACGAAATTCCTTTCACCGTAACCTCAA
TCGCGAACGGCGGCAGCAGCACGAACACGGAACTCAAAAAAGCCGTCTTGGGGCTGACCGTTACGCCGAACATCACGCCC
GACGGCCAAATCATTATGACCGTCAAAATCAACAAGGACTCGCCTGCGCAATGTGCCTCCGGTAATCAGACGATTCTGTG
TATTTCGACCAAAAACCTGAATACGCAGGCTATGGTTGAAAACGGCGGCACATTGATTGTCGGCGGTATTTATGAAGAAG
ACAACGGTAATACGCTGACCAAAGTCCCCCTGTTGGGCGACATCCCCGTTATCGGCAACCTCTTTAAAACACGCGGGAAA
AAACCCGACCGCCGCGAACTGCTGATTTTCATTACCCCGAGGATTATGGGTACGGCCGGCAACAGCCTGCGCTATTGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(577-736)

Bacterial type II/III secretion system short domain (Secretin_N)

(420-491)

Secretin and TonB N terminus short domain (STN)

(347-392)

AMIN domain (AMIN)

(43-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

96.489

100

0.996
  pilQ Neisseria meningitidis M1080

97.503

100

0.996
  pilQ Neisseria gonorrhoeae strain FA1090

92.617

100

0.926

Multiple sequence alignment