Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A9C00_RS12095 Genome accession   NZ_CP015912
Coordinates   2394098..2394730 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 210205630     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2389098..2399730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9C00_RS12065 (A9C00_12065) yheS 2389267..2391180 (+) 1914 WP_065304247.1 ABC transporter ATP-binding protein -
  A9C00_RS12070 (A9C00_12070) yheT 2391180..2392202 (+) 1023 WP_000057356.1 hydrolase -
  A9C00_RS12075 (A9C00_12075) yheU 2392196..2392414 (+) 219 WP_000907085.1 YheU family protein -
  A9C00_RS12080 (A9C00_12080) prkB 2392468..2393337 (+) 870 WP_001274680.1 phosphoribulokinase -
  A9C00_RS12085 (A9C00_12085) yhfA 2393392..2393796 (-) 405 WP_001148908.1 OsmC family protein -
  A9C00_RS12095 (A9C00_12095) crp 2394098..2394730 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A9C00_RS12100 (A9C00_12100) yhfK 2394781..2396871 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A9C00_RS12105 (A9C00_12105) argD 2396938..2398158 (-) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A9C00_RS12110 (A9C00_12110) pabA 2398244..2398807 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  A9C00_RS12115 (A9C00_12115) fic 2398839..2399441 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  A9C00_RS12120 (A9C00_12120) yhfG 2399431..2399598 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=156323 A9C00_RS12095 WP_000242755.1 2394098..2394730(+) (crp) [Escherichia coli strain 210205630]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=156323 A9C00_RS12095 WP_000242755.1 2394098..2394730(+) (crp) [Escherichia coli strain 210205630]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment