Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   RN80_RS05045 Genome accession   NZ_CP012646
Coordinates   1033983..1034573 (+) Length   196 a.a.
NCBI ID   WP_000613471.1    Uniprot ID   A0A1E9GI28
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context


Location: 1028983..1039573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS05015 (RN80_05035) - 1029062..1029802 (+) 741 WP_060627912.1 MerR family transcriptional regulator -
  RN80_RS05020 (RN80_05040) - 1029845..1031020 (-) 1176 WP_004256803.1 NAD(P)/FAD-dependent oxidoreductase -
  RN80_RS05025 (RN80_05045) - 1031078..1031923 (-) 846 WP_004256807.1 DegV family protein -
  RN80_RS05030 (RN80_05050) - 1032048..1032605 (+) 558 WP_000004136.1 TetR/AcrR family transcriptional regulator -
  RN80_RS05035 (RN80_05055) - 1032624..1033091 (+) 468 WP_000136976.1 deoxycytidylate deaminase -
  RN80_RS05040 (RN80_05060) upp 1033180..1033809 (+) 630 WP_000515974.1 uracil phosphoribosyltransferase -
  RN80_RS05045 (RN80_05065) clpP 1033983..1034573 (+) 591 WP_000613471.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  RN80_RS05050 (RN80_05070) - 1034652..1034939 (+) 288 WP_000462127.1 YlbG family protein -
  RN80_RS05055 (RN80_05075) - 1035006..1036166 (+) 1161 WP_045611943.1 ABC transporter substrate-binding protein -
  RN80_RS05060 (RN80_05080) - 1036281..1037150 (+) 870 WP_060627914.1 branched-chain amino acid ABC transporter permease -
  RN80_RS05065 (RN80_05085) - 1037154..1038110 (+) 957 WP_000662286.1 branched-chain amino acid ABC transporter permease -
  RN80_RS05070 (RN80_05090) - 1038110..1038874 (+) 765 WP_001185995.1 ABC transporter ATP-binding protein -

Sequence


Protein


Download         Length: 196 a.a.        Molecular weight: 21352.38 Da        Isoelectric Point: 4.4910

>NTDB_id=156019 RN80_RS05045 WP_000613471.1 1033983..1034573(+) (clpP) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNILEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=156019 RN80_RS05045 WP_000613471.1 1033983..1034573(+) (clpP) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGATTCCTGTAGTTATTGAACAAACAAGTCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATCATGCTGACAGGTCCAGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGACA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCAGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACTATCGTTATGGGGATGGCTGCATCTATGGGGACTGTCATCGCGTCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTATATGATCCACCAACCAATGGGTGGTACAGGTGGTGGTACTCAACAAA
CCGATATGGCGATTGCTGCAGAACACTTGCTCAAAACTCGTAACATCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGCGATAATTGGATGAGCGCCCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA

Domains


Predicted by InterproScan.

(11-192)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A1E9GI28

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

98.98

100

0.99

  clpP Streptococcus pneumoniae D39

98.98

100

0.99

  clpP Streptococcus pneumoniae R6

98.98

100

0.99

  clpP Streptococcus pneumoniae TIGR4

98.98

100

0.99

  clpP Streptococcus thermophilus LMG 18311

93.333

99.49

0.929

  clpP Streptococcus thermophilus LMD-9

93.333

99.49

0.929

  clpP Streptococcus pyogenes JRS4

91.282

99.49

0.908

  clpP Streptococcus pyogenes MGAS315

91.282

99.49

0.908

  clpP Streptococcus mutans UA159

86.224

100

0.862

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

85.128

99.49

0.847

  clpP Lactococcus lactis subsp. cremoris KW2

84.615

99.49

0.842

  clpP Bacillus subtilis subsp. subtilis str. 168

58.854

97.959

0.577

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.549

98.469

0.577


Multiple sequence alignment