Detailed information NTG0155972

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: RN80_RS00750
• Genome accession: NZ_CP012646
• Coordinates: 135460..136470 (-)
• Length: 336 a.a.
• NCBI ID: WP_001090628.1
• Uniprot ID: F9HAD8
• Organism: Streptococcus mitis strain KCOM 1350 (= ChDC B183)
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 130460..141470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RN80_RS00720 (RN80_00725)	-	131751..132053 (-)	303	WP_060627182.1	hypothetical protein	-
RN80_RS00725 (RN80_00730)	-	132215..132667 (+)	453	WP_000079148.1	universal stress protein	-
RN80_RS00735 (RN80_00740)	-	132804..134195 (-)	1392	WP_060627183.1	Cof-type HAD-IIB family hydrolase	-
RN80_RS00740 (RN80_00745)	-	134261..135223 (+)	963	WP_060627184.1	asparaginase	-
RN80_RS00750 (RN80_00755)	ccpA	135460..136470 (-)	1011	WP_001090628.1	catabolite control protein A	Regulator
RN80_RS00755 (RN80_00760)	-	136709..137026 (+)	318	WP_000886035.1	DUF960 domain-containing protein	-
RN80_RS00760 (RN80_00765)	folK	137072..137884 (-)	813	WP_049492759.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
RN80_RS00765 (RN80_00770)	folE	138043..138597 (-)	555	WP_000380916.1	GTP cyclohydrolase I FolE	-
RN80_RS00770 (RN80_00775)	-	138578..139900 (-)	1323	WP_060627185.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
RN80_RS00775 (RN80_00780)	folP	139902..140876 (-)	975	WP_060627186.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37155.16 Da
• Isoelectric Point: 5.3350

>NTDB_id=155972 RN80_RS00750 WP_001090628.1 135460..136470(-) (ccpA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQVSRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=155972 RN80_RS00750 WP_001090628.1 135460..136470(-) (ccpA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACAGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAACACCCGTAAAAAAGTGCTTGAGGTGATTGACCGTTTGGATTACCGTCCAAATG
CAGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTTGTGATCCCCAATATCACTAATGGTTATTTCTCA
ACGCTTGCCAAAGGGATTGATGATATCGCTGAAATGTACAAGTATAACATCGTCCTTGCTAATAGTGATGAGGATGATGA
CAAGGAAGTTTCAGTTGTCAATACCCTGTTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGGTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGAACACCAGTTGTTCTTGCGGGAACAGTAGATGTGGAACACCAGCTTCCAAGT
GTCAATATTGACTACAAACAAGCTACGATTGATGCAGTGACCTACCTTGCTAAAGAAAATGAGCGCATTGCTTTTGTTAG
CGGTCCACTAGTGGATGATATCAATGGTAAGGTTCGTTTGGTTGGTTACAAGGAAGCCTTGAAAAAAGCAGGGATTTCTT
ATAGCGAAGGATTGGTATTTGAGTCTAAATACACTTATGAAGACGGTTATGCCTTGGCAGAACGCTTAATTTCATCAAAT
GCAACTGCAGCAGTTGTAACAGGTGATGAACTGGCAGCAGGTGTCTTGAACGGCCTTGCTGATAAGGGCGTATCAGTACC
AGAAGAGTTTGAAATTATTACTAGTGATGATTCGCAAGTCTCACGCTTTACCCGTCCAAACTTGACAACTATCGCCCAAC
CTCTTTATGACCTTGGCGCTATTAGCATGCGTATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGTTCAACACGAAAACGGAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: F9HAD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.238	100	0.952
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.222	99.405	0.887
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568