Detailed information NTG0155369

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: A6688_RS24835
• Genome accession: NZ_CP012580
• Coordinates: 5390660..5391997 (+)
• Length: 445 a.a.
• NCBI ID: WP_003110427.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain PA_D9
• Function: regulate pilin expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	5392043..5400167	5390660..5391997	flank	46

Gene organization within MGE regions

Location: 5390660..5400167

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6688_RS24835 (A6688_24835)	pilR	5390660..5391997 (+)	1338	WP_003110427.1	two-component system response regulator PilR	Regulator
A6688_RS24840 (A6688_24840)	thiO	5392043..5393137 (-)	1095	WP_033944813.1	glycine oxidase ThiO	-
A6688_RS24845 (A6688_24845)	-	5393277..5393777 (+)	501	WP_016254062.1	GspH/FimT family pseudopilin	-
A6688_RS24850 (A6688_24850)	-	5393900..5394388 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
A6688_RS24855 (A6688_24855)	pilV	5394398..5394922 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
A6688_RS24860 (A6688_24860)	-	5394931..5395746 (+)	816	WP_034027589.1	PilW family protein	-
A6688_RS24865 (A6688_24865)	-	5395743..5396348 (+)	606	WP_003116263.1	pilus assembly PilX family protein	-
A6688_RS24870 (A6688_24870)	-	5396362..5399838 (+)	3477	WP_034027586.1	pilus assembly protein	-
A6688_RS24875 (A6688_24875)	-	5399841..5400167 (+)	327	WP_016254060.1	PilY2 family type 4a fimbrial biogenesis protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49723.03 Da
• Isoelectric Point: 5.8638

>NTDB_id=155369 A6688_RS24835 WP_003110427.1 5390660..5391997(+) (pilR) [Pseudomonas aeruginosa strain PA_D9]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLADRI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=155369 A6688_RS24835 WP_003110427.1 5390660..5391997(+) (pilR) [Pseudomonas aeruginosa strain PA_D9]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGCCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCTACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGATCGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGATATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Response regulator receiver domain (Response_reg) (7-115)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	99.775	100	0.998
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384