Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DE8555_RS01990 Genome accession   NZ_CP012393
Coordinates   375921..379049 (-) Length   1042 a.a.
NCBI ID   WP_079886198.1    Uniprot ID   A0AAC9CT71
Organism   Neisseria meningitidis strain DE8555     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 370921..384049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DE8555_RS13470 - 371484..371651 (-) 168 WP_153312129.1 hypothetical protein -
  DE8555_RS01965 (DE8555_0357) - 371655..372044 (-) 390 WP_002221514.1 DUF559 domain-containing protein -
  DE8555_RS01980 (DE8555_0358) - 372624..372761 (-) 138 WP_002214606.1 VOC family protein -
  DE8555_RS01985 (DE8555_0359) carA 372807..373940 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DE8555_RS01990 (DE8555_0360) pilC 375921..379049 (-) 3129 WP_079886198.1 PilC family type IV pilus tip adhesin Machinery gene
  DE8555_RS01995 (DE8555_0361) apbC 380003..381082 (-) 1080 WP_002248129.1 iron-sulfur cluster carrier protein ApbC -
  DE8555_RS02005 (DE8555_0362) - 381452..381961 (+) 510 WP_002221509.1 protein disulfide oxidoreductase -
  DE8555_RS02015 (DE8555_0363) nadR 382304..382744 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  DE8555_RS02020 (DE8555_0364) hpaC 382859..383359 (+) 501 WP_002221506.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1042 a.a.        Molecular weight: 113850.58 Da        Isoelectric Point: 9.7401

>NTDB_id=154151 DE8555_RS01990 WP_079886198.1 375921..379049(-) (pilC) [Neisseria meningitidis strain DE8555]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTYKYAIIMNEQNQPKVKQEGSYSTLREKDRERKFIYNKGGSGGGSVS
FNNSDELVSQQSGTAVFGTATYLPPYGKVSGFDADALKERNNALNWINTTRPGLAGYSYANVICRDTRQCPQLFYETKFA
FSNKDLVNNAGRLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSEGTAKDGKVSNKLISSFSEDNNNQTIVSTTRDHPISL
GDQQREHTAMAYYLNAKLHLLDKKGIKDIAQGKTVDLGTLRPRVETKTNNWGNLLNFWVTWKIEDNGQIPVKLGLPEVKA
GRCTNAAHPNSKAKPPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPGRPGRYSLAALDAQNI
KSHEPRFNGRQTVIRLPGGVYKISLGRNGGRVAGINGNDGKNDTFGIFKDRYVTPEADEWSEMLLPWTVRAFNDDGRFNT
VNKEENNGKPKYSQRYRIRENGNNGKRDLGDIVNSPIVAVGGYLATSANDGMVHIFKQSGGDKRGYNLKLSYIPGTMPRK
NIENNDSTLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGFGGRGAYALDLTKADSNDPTKASLFD
VKDNGNNGNNGNNGNNGNNGNNRVELGYTVGTPQIGKTHDGKYAAFLASGYATKDINNGENKTALYVYDLESSGTLIKKI
DVPGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGKMYRFDLKDWSVRTIFQGTKPITSAPAISQLKDKRVVIFGTGSDLSE
EDVDNNDIQSIYGIFDDDTATTGTVNFSGTGGGLLEQVLKQEGKTLFLTDYKRSDGSGDKGWVVKLKDGQRVTVKPTVVL
RTAFVTIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPEANQAVAQYSGHKKTASGKSIPIGCMEKDGGTVCPNG
YVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREI
FY

Nucleotide


Download         Length: 3129 bp        

>NTDB_id=154151 DE8555_RS01990 WP_079886198.1 375921..379049(-) (pilC) [Neisseria meningitidis strain DE8555]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCTATAAATACGCTATTATCATGAACGAACAAAATCAGCCGAAGGTAAAGCAGGAGGGTT
CATATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAGGCGGATCGGGTGGAGGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCAACAATGCCCTTAATTGGATTAATACGACCCGCCCGGGGT
TGGCAGGCTACTCCTACGCCAACGTCATATGCAGAGACACAAGGCAATGCCCCCAACTTTTCTATGAGACCAAATTTGCC
TTCAGCAACAAAGATTTGGTAAACAATGCGGGCAGGCTGGATAGGCACCCGGACCCAAGCCGCGAAAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGGGTACCGCCAAAGATGGCAAGGTATCCA
ACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACACGAGACCACCCTATTTCCCTT
GGCGACCAGCAGCGCGAACATACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGATTAA
AGATATCGCCCAAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGACGAAGACAAATAATTGGGGGAATC
TGCTAAATTTTTGGGTTACGTGGAAGATTGAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAAGTCAAAGCC
GGGCGCTGCACCAACGCCGCCCACCCCAATTCCAAAGCCAAACCCCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTT
CGGCCCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGGCAGTTCGAGCAGCCGCATCT
TCCTCCAAGAGCTGAAAACTCAAACCGACCCCGGCAGGCCCGGCCGGTATTCCCTCGCCGCTTTGGATGCGCAGAACATC
AAAAGCCACGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGCCGGGCGGCGTGTACAAGATCAGCCTGGGCAG
GAACGGCGGCCGGGTCGCGGGTATTAATGGCAATGACGGCAAAAACGACACTTTCGGCATCTTCAAGGACAGGTATGTCA
CACCTGAGGCCGACGAGTGGAGCGAAATGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACA
GTCAACAAAGAAGAAAACAACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAAGCG
TGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGGCAACTTCTGCCAACGACGGGATGGTGC
ATATCTTCAAACAAAGCGGCGGGGACAAGCGCGGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAG
AATATTGAAAACAACGACTCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGG
CGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACACTTCTTTATGTTCGGCGCAATGG
GCTTTGGCGGCAGAGGCGCGTATGCCTTGGATTTGACCAAAGCCGACAGCAATGACCCGACAAAAGCCTCTTTGTTTGAT
GTAAAAGATAACGGCAATAATGGCAATAACGGCAATAACGGCAATAACGGCAATAACGGCAATAATCGCGTGGAATTAGG
CTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACGACGGCAAATACGCCGCTTTCCTCGCCTCTGGTTATGCGACTA
AAGACATTAACAACGGCGAGAATAAAACCGCGCTGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATC
GATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTA
TGCCGGCGATCGCGGCGGCAAGATGTACCGCTTTGATTTGAAAGACTGGTCTGTACGCACTATTTTCCAAGGCACGAAGC
CGATTACTTCCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAG
GAAGATGTTGATAATAATGATATACAATCTATTTACGGTATTTTTGACGACGATACGGCGACGACGGGTACTGTAAACTT
CAGCGGTACGGGAGGCGGGCTGCTCGAGCAAGTGCTTAAGCAGGAGGGTAAAACCTTATTCCTGACCGATTATAAGCGAT
CCGACGGCTCGGGCGACAAGGGCTGGGTAGTGAAATTGAAGGACGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTG
CGTACCGCCTTTGTAACCATCCATAAATATACGGGTAATGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATAC
CGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGAAGCCAATCAGGCTGTCGCGCAATATTCCG
GTCATAAGAAAACCGCCAGCGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGACGGGGGAACCGTCTGCCCGAACGGA
TATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGATTTCCCCGTCACGGCAGACGGTGA
TGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCA
CCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAATC
TTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(509-849)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

79.202

100

0.8

Multiple sequence alignment