Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DE8669_RS00260 Genome accession   NZ_CP012391
Coordinates   45744..48929 (+) Length   1061 a.a.
NCBI ID   WP_079870325.1    Uniprot ID   -
Organism   Neisseria meningitidis strain DE8669     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 40744..53929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DE8669_RS00240 (DE8669_0048) - 41059..41907 (+) 849 WP_002215243.1 mechanosensitive ion channel family protein -
  DE8669_RS00245 (DE8669_0049) - 41933..42418 (+) 486 WP_002221794.1 CinA family protein -
  DE8669_RS00250 (DE8669_0050) msrAB 42520..44088 (-) 1569 WP_002216163.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  DE8669_RS00255 (DE8669_0051) pilA 44234..45499 (+) 1266 WP_002228837.1 signal recognition particle-docking protein FtsY Machinery gene
  DE8669_RS00260 (DE8669_0052) pilC 45744..48929 (+) 3186 WP_079870325.1 PilC family type IV pilus tip adhesin Machinery gene
  DE8669_RS00265 (DE8669_0053) yccS 49460..51610 (-) 2151 WP_014582356.1 YccS family putative transporter -
  DE8669_RS00270 (DE8669_0054) - 51896..53122 (-) 1227 WP_002218483.1 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 1061 a.a.        Molecular weight: 116777.01 Da        Isoelectric Point: 9.6935

>NTDB_id=154054 DE8669_RS00260 WP_079870325.1 45744..48929(+) (pilC) [Neisseria meningitidis strain DE8669]
MNKTWKRQVFRHTALYTAILMFSHTGGGGAQAQTQTQTQTHKYAIVMNGQKLPEVKWGTGYRNLAQKSNERQFTHTSGFG
IKKNVTLSFNNTDEVVAQKNGTVVFGAATYLPPYGKVSGFDTAKLTERGKAVDWIRTTHPGLIGYSYENVTCSNNYYNAS
SGCPELSYKTQFTFGNQGLKRKTNGRLDIDEDKSRDGSPIYKLQNYPWLGVSFNLSSESLVKSIKYNKIISSFSEDVTQS
NGTNSQYKDKNLVYTTGDYQYKNKYSSRYVGQDEHSAVAFYLNAKLHLLDKKQIQNIAQVSELNFGTLRTLIEPTEEWKK
KRTNFFQGGNWTFEDKGEVSVKLKLPEVKAGRCVNKNNPNPNAKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSS
SQIFLQNLSRKDDTSKPGRYSLKPLSMSEIKSKEPNFTGRQTVIRLDSGVQQIKLQGNEVANFNGNDGKNDTFGIVSEGS
FMPDTSEWKKVLLPWTVRASNDDGQFNTFNKEENNGKPKYSQKYRSRDSSKHERNLGDIVNSPIVAVGGYLATSANDGMV
HIFKKGNGVDERNYSLKLSYIPGTMPRQYFDNDTSALKDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVEWKGQNRVFM
FGAMGLGGRGAYALDLTKAENGDPTAVSLFDVKNDKNKGNNSAELGYTVGTPQIGKTHDGKYAAFLASGYATKTIDSTDN
KTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGSMYRFDLKDWSVRTIFSGNKPITSAPAI
SQLKDKRVVIFGTGSDLSEEDVLNTDEQYIYGIFDDDTAASNVDVKLKGLGGGLLEQVLEQKDKTLFLTDYKRSDGSGNK
GWVVKLKDGQRVTVKPTVVLRTAFVTIRKYKDNGCGAETAILGINTADGGKLTKKSARPIVPDTNTAVAQYSGHKKGTNG
KSIPIGCMQKGNEIVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPDGKRAGKNNRCFSQKGVRTLLMNDLD
SLDITGPTCGMKRISWREVFF

Nucleotide


Download         Length: 3186 bp        

>NTDB_id=154054 DE8669_RS00260 WP_079870325.1 45744..48929(+) (pilC) [Neisseria meningitidis strain DE8669]
ATGAATAAAACTTGGAAACGGCAGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGCAAACGCAAACGCAAACGCAAACGCATAAATACGCTATTGTAATGAACGGACAAAAGCTGCCCG
AGGTAAAGTGGGGGACTGGCTATAGAAATTTGGCGCAAAAAAGCAATGAACGCCAATTTACCCATACGAGTGGTTTCGGC
ATCAAAAAAAACGTAACTTTATCATTCAATAATACCGATGAAGTTGTTGCTCAAAAAAACGGTACTGTCGTTTTCGGCGC
GGCGACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGCTAAGCTGACCGAGCGCGGCAAAGCCGTTGATT
GGATTCGTACGACCCACCCGGGGTTGATAGGCTACAGCTACGAAAATGTCACATGCAGCAATAACTACTACAACGCCAGC
AGCGGCTGTCCTGAACTTAGCTATAAAACCCAATTTACCTTTGGTAATCAAGGGTTGAAAAGAAAGACAAACGGCAGGCT
GGATATAGACGAAGACAAAAGCCGCGACGGTTCGCCCATTTACAAATTGCAGAATTATCCCTGGTTGGGCGTGTCTTTCA
ATTTGAGCAGCGAGAGCCTCGTCAAATCAATAAAATACAATAAAATTATATCTTCTTTTAGCGAGGACGTGACGCAGAGC
AATGGTACGAACAGCCAATACAAAGACAAAAACCTCGTTTATACGACAGGCGATTACCAGTATAAGAATAAATATTCTTC
CCGTTATGTCGGGCAGGACGAACACTCCGCCGTCGCCTTTTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAACAAA
TCCAAAATATCGCGCAAGTCAGTGAACTTAATTTTGGTACGTTGAGAACGCTCATCGAGCCGACGGAAGAGTGGAAAAAA
AAGAGGACGAACTTTTTTCAAGGTGGTAATTGGACGTTTGAAGATAAAGGAGAAGTCAGCGTCAAACTCAAATTGCCGGA
AGTCAAAGCAGGCCGCTGCGTCAACAAAAATAACCCCAATCCCAATGCCAAAGCCCCCTCCCCCGCACTGACCGCCCCCG
CGCTGTGGTTCGGACCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGC
AGCCAAATTTTCCTGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTAT
GTCGGAGATTAAAAGTAAAGAGCCGAATTTCACAGGGCGGCAAACCGTCATCCGATTGGATAGCGGCGTACAGCAGATCA
AACTTCAAGGCAATGAGGTCGCCAATTTTAATGGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAAGGGAGC
TTCATGCCTGATACCAGCGAGTGGAAAAAAGTATTGCTGCCTTGGACGGTTCGTGCTTCCAATGATGACGGTCAATTTAA
CACATTCAACAAAGAAGAAAACAACGGCAAGCCAAAATACAGTCAAAAATACCGCAGCCGCGACAGCAGCAAGCACGAGC
GCAATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGGCTACTTCCGCCAACGACGGGATGGTG
CATATCTTCAAAAAAGGCAACGGCGTGGACGAGCGCAACTATAGTCTGAAGCTCAGTTATATCCCCGGCACGATGCCGCG
CCAATATTTTGATAACGACACTTCCGCTCTCAAAGACTCCACCCTCGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCT
ATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTACGCCAAGTCGAATGGAAAGGGCAAAACCGCGTGTTTATG
TTCGGCGCGATGGGCCTTGGCGGCAGAGGTGCGTATGCCTTGGATTTGACCAAAGCCGAAAACGGTGACCCGACCGCCGT
TTCCCTGTTTGATGTCAAAAATGACAAAAATAAAGGCAATAATAGTGCAGAATTAGGCTACACCGTCGGCACGCCGCAAA
TCGGCAAAACCCACGACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAAT
AAAACCGCGCTGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGG
GCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGCAGTA
TGTACCGCTTTGATTTGAAAGACTGGTCTGTACGCACCATTTTCAGCGGCAACAAACCGATTACTTCCGCGCCCGCTATT
TCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAGGAGGATGTACTCAATACGGACGA
ACAATATATTTACGGTATCTTTGACGACGATACGGCGGCGAGTAATGTAGATGTAAAACTCAAAGGTTTGGGAGGCGGGT
TGCTCGAGCAGGTGCTTGAGCAGAAGGATAAAACCTTATTCCTGACCGATTATAAGCGATCCGACGGCTCGGGCAATAAG
GGCTGGGTAGTGAAATTGAAGGACGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCAT
CCGCAAATATAAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCA
AGAAAAGCGCGCGCCCGATTGTGCCGGACACCAATACGGCTGTCGCGCAATATTCCGGCCATAAGAAAGGCACCAACGGC
AAATCCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAA
TGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACC
CCGACGGCAAGCGTGCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGAC
AGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(536-869)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

71.773

100

0.729

Multiple sequence alignment