Detailed information NTG0153770

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: A6R75_RS13080
• Genome accession: NZ_CP015377
• Coordinates: 2794080..2794724 (-)
• Length: 214 a.a.
• NCBI ID: WP_003085214.1
• Uniprot ID: A0A0H2ZLY6
• Organism: Pseudomonas aeruginosa strain BAMCPA07-48
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2789080..2799724

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6R75_RS13045 (A6R75_13045)	-	2789203..2789433 (+)	231	WP_003118928.1	hypothetical protein	-
A6R75_RS13050 (A6R75_13050)	-	2789529..2790581 (+)	1053	WP_009315200.1	pyocin knob domain-containing protein	-
A6R75_RS13055 (A6R75_13055)	-	2790581..2790883 (+)	303	WP_003113177.1	hypothetical protein	-
A6R75_RS13060 (A6R75_13060)	-	2790880..2791110 (+)	231	WP_003113176.1	hypothetical protein	-
A6R75_RS13065 (A6R75_13065)	-	2791529..2792134 (+)	606	WP_023092374.1	aminodeoxychorismate/anthranilate synthase component II	-
A6R75_RS13070 (A6R75_13070)	trpD	2792136..2793185 (+)	1050	WP_003085203.1	anthranilate phosphoribosyltransferase	-
A6R75_RS13075 (A6R75_13075)	trpC	2793182..2794018 (+)	837	WP_003085205.1	indole-3-glycerol phosphate synthase TrpC	-
A6R75_RS13080 (A6R75_13080)	crp	2794080..2794724 (-)	645	WP_003085214.1	cAMP-activated global transcriptional regulator CRP	Regulator
A6R75_RS13085 (A6R75_13085)	-	2794995..2795417 (+)	423	WP_003085219.1	OsmC family protein	-
A6R75_RS13090 (A6R75_13090)	speD	2795737..2796530 (+)	794	Protein_2621	adenosylmethionine decarboxylase	-
A6R75_RS13095 (A6R75_13095)	coq7	2796585..2797232 (-)	648	WP_003085224.1	2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase	-
A6R75_RS13100 (A6R75_13100)	-	2797332..2797669 (-)	338	Protein_2623	histidine triad nucleotide-binding protein	-
A6R75_RS13105 (A6R75_13105)	-	2797748..2799229 (+)	1482	WP_003121853.1	AAA family ATPase	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24225.01 Da
• Isoelectric Point: 8.0525

>NTDB_id=153770 A6R75_RS13080 WP_003085214.1 2794080..2794724(-) (crp) [Pseudomonas aeruginosa strain BAMCPA07-48]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide

• Length: 645 bp

>NTDB_id=153770 A6R75_RS13080 WP_003085214.1 2794080..2794724(-) (crp) [Pseudomonas aeruginosa strain BAMCPA07-48]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGTGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGGAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (22-114)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-209)

3D structure

• AlphaFold DB: A0A0H2ZLY6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	67.327	94.393	0.636
crp	Haemophilus influenzae Rd KW20	60.396	94.393	0.57
crp	Acinetobacter baumannii D1279779	54.545	92.523	0.505