Detailed information NTG0153133

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V471_RS03110
• Genome accession: NZ_CP015283
• Coordinates: 594521..597079 (+)
• Length: 852 a.a.
• NCBI ID: WP_084871096.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ATCC 25975
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 589521..602079

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V471_RS03090 (V471_03060)	purB	589720..591018 (+)	1299	WP_002886310.1	adenylosuccinate lyase	-
V471_RS03095 (V471_03065)	argS	591895..593586 (-)	1692	WP_002886311.1	arginine--tRNA ligase	-
V471_RS03100 (V471_03070)	argR	593741..594169 (+)	429	WP_172453860.1	arginine repressor	-
V471_RS03105 (V471_03075)	-	594169..594528 (+)	360	WP_084871095.1	YlbF family regulator	-
V471_RS03110 (V471_03080)	hexA	594521..597079 (+)	2559	WP_084871096.1	DNA mismatch repair protein MutS	Machinery gene
V471_RS03115 (V471_03085)	-	597113..597568 (-)	456	WP_084871097.1	DUF3021 domain-containing protein	-
V471_RS03120 (V471_03090)	brsR	597565..598002 (-)	438	WP_014633775.1	LytTR family DNA-binding domain-containing protein	Regulator
V471_RS03125 (V471_03095)	-	598181..598486 (+)	306	WP_002886319.1	hypothetical protein	-
V471_RS03130 (V471_03100)	hexB	598536..600479 (+)	1944	WP_084869677.1	DNA mismatch repair endonuclease MutL	Machinery gene
V471_RS03135 (V471_03105)	-	600610..600831 (+)	222	WP_002886321.1	hypothetical protein	-
V471_RS03140 (V471_03110)	ruvA	600989..601579 (+)	591	WP_004181981.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95526.67 Da
• Isoelectric Point: 4.6635

>NTDB_id=153133 V471_RS03110 WP_084871096.1 594521..597079(+) (hexA) [Streptococcus salivarius strain ATCC 25975]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLSEADEQILVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIVERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPAFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNTLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIRPQEKVSPQ
EKPATETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=153133 V471_RS03110 WP_084871096.1 594521..597079(+) (hexA) [Streptococcus salivarius strain ATCC 25975]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTT
CCGTATGGGTGATTTTTACGAATTATTTTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTC
GTAATAAGAACGCCGATAATCCCATTCCTATGGCTGGTGTTCCTTATCATTCAGCTCAATCTTATATTGATGTCTTGGTT
GAGATGGGCTACAAGGTAGCCATTGCTGAGCAGATGGAGGACCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGT
TCAGGTTATCACGCCAGGTACAGTGGTTGACAGTTCTAAACCTGATAATGCCAATAATTTCTTGGTAGCTATTGACAAGG
CTGGAAGTCGATTCGGCCTGGCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTGGTTGGTTATGATTTATCCGAAGCTGATGAACAAATTTT
GGTGAAGCAACTCAACCTTCTACTTTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAG
ATTTGGAAAGCAGTGTAGCGGGTAAACTTCTCCAGTATGTGCACCGTACTCAGATGCGTGAGCTCAGCCATTTACAAAAA
GCTCAGCACTATGAGATTAAGGATTACTTGCAGATGTCCTATGCGACCAAGTCGAGTTTGGATTTACTGGAAAATGCTAG
AACAGGTAAGAAACATGGTTCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTACGTACTT
GGATTGATAGACCTTTAGTAAATCAGGCTGCAATCGTGGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTC
GAGCGTAGTGATCTGACTGAGAGTCTTAAAGGGGTTTACGATATTGAGCGCCTGGCCAGCCGTGTTTCCTTTGGAAAGGC
TAATCCTAAAGATTTGATTCAGCTAGGTCATACCCTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATG
ACGAGGCCTTGTCACGTCTTTTACAAGAGCTAGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATTGATCCC
GATGCTCCTGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGTGAGGGGACATCATGGATTGCGGATATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTACTACTTCCATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCA
ACCCTGAAAAATTCAGAGCGTTTTGGAACTGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTTGAGGCACGTGAAAAATC
ATCAACGCTAGAGTATGATATTTTCATGCGTGTCCGTGAGCAGGTGGAACGCTATATTGACCGTTTGCAATCTTTGGCTA
AGGCCATTGCGACAGTCGATGTGCTTCAGAGTTTAGCAGTTACAGCAGAGACGAATCATTATGTTCGTCCTGCGTTCAAT
GATGAGCATCGTATCGTTATTGATCAAGGCCGTCATGCGGTGGTTGAGAAGGTTATGGGTGTTCAGGAATACATTCCAAA
CACGATTACCTTTGACAGTCAGACCAATGTTCAGCTCATCACAGGGCCAAATATGAGTGGTAAATCTACCTATATGCGTC
AGTTGGCTTTGTCAGTCGTTATGGCTCAGATGGGCTCTTACGTACCAGCAGATAGTATTGATTTGCCAGTTTTTGATGCC
ATCTATACACGTATTGGTGCTGCAGATGACCTGATTTCAGGTCAGTCAACCTTCATGGTTGAGATGATGGAAGCTAATCA
GGCTATTAAGCGGGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCCACCTATGATGGTATGG
CTCTAGCTCAGTCTATCATTGAGTTTATTCATGACAAGGTAGGAGCTAAAACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAATACTTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCT
TCACAAGATTGTCGATGGCCCAGCTGACAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACCATCTTGACACAATTAGAGGGCGAGACAGTTACCATCCGACCTCAGGAAAAGGTATCGCCTCAA
GAGAAGCCAGCCACTGAAACACATGTCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCGGTTCTTCAAGA
GTTACGTGATTTGGACATTTACAATATGACACCGATGCAGGTCATGATGGCTGTAGCGGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.326	100	0.744
mutS	Pseudomonas stutzeri strain ATCC 17587	36.185	100	0.367