Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A5955_RS08270 Genome accession   NZ_CP015241
Coordinates   1637630..1638262 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4465     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1632630..1643262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A5955_RS08240 (A5955_08235) yheS 1632799..1634712 (+) 1914 WP_000634825.1 ABC transporter ATP-binding protein -
  A5955_RS08245 (A5955_08240) yheT 1634712..1635734 (+) 1023 WP_000057377.1 hydrolase -
  A5955_RS08250 (A5955_08245) yheU 1635728..1635946 (+) 219 WP_000907085.1 YheU family protein -
  A5955_RS08255 (A5955_08250) prkB 1636000..1636869 (+) 870 WP_001274677.1 phosphoribulokinase -
  A5955_RS08260 (A5955_08255) yhfA 1636924..1637328 (-) 405 WP_001148908.1 OsmC family protein -
  A5955_RS08270 (A5955_08265) crp 1637630..1638262 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A5955_RS08275 (A5955_08270) yhfK 1638313..1640403 (+) 2091 WP_001353634.1 YccS/YhfK family putative transporter -
  A5955_RS08280 (A5955_08275) argD 1640470..1641690 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A5955_RS08285 (A5955_08280) pabA 1641776..1642339 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  A5955_RS08290 (A5955_08285) fic 1642371..1642973 (-) 603 WP_001280661.1 putative adenosine monophosphate-protein transferase Fic -
  A5955_RS08295 (A5955_08290) yhfG 1642963..1643130 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=152847 A5955_RS08270 WP_000242755.1 1637630..1638262(+) (crp) [Escherichia coli strain 2013C-4465]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=152847 A5955_RS08270 WP_000242755.1 1637630..1638262(+) (crp) [Escherichia coli strain 2013C-4465]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment