Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A5956_RS08570 Genome accession   NZ_CP015240
Coordinates   1579843..1580475 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2011C-3911     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1574843..1585475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A5956_RS08540 (A5956_07885) yheS 1575012..1576925 (+) 1914 WP_000634810.1 ABC transporter ATP-binding protein -
  A5956_RS08545 (A5956_07890) yheT 1576925..1577947 (+) 1023 WP_000057405.1 hydrolase -
  A5956_RS08550 (A5956_07895) yheU 1577941..1578159 (+) 219 WP_000907085.1 YheU family protein -
  A5956_RS08555 (A5956_07900) prkB 1578213..1579082 (+) 870 WP_001274680.1 phosphoribulokinase -
  A5956_RS08560 (A5956_07905) yhfA 1579137..1579541 (-) 405 WP_001148908.1 OsmC family protein -
  A5956_RS08570 (A5956_07915) crp 1579843..1580475 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A5956_RS08575 (A5956_07920) yhfK 1580526..1582616 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A5956_RS08580 (A5956_07925) argD 1582683..1583903 (-) 1221 WP_000963784.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A5956_RS08585 (A5956_07930) pabA 1583989..1584552 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  A5956_RS08590 (A5956_07935) fic 1584584..1585186 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  A5956_RS08595 (A5956_07940) yhfG 1585176..1585343 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=152772 A5956_RS08570 WP_000242755.1 1579843..1580475(+) (crp) [Escherichia coli strain 2011C-3911]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=152772 A5956_RS08570 WP_000242755.1 1579843..1580475(+) (crp) [Escherichia coli strain 2011C-3911]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467