Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   PA8281_RS03530 Genome accession   NZ_CP015002
Coordinates   742053..742697 (-) Length   214 a.a.
NCBI ID   WP_003085214.1    Uniprot ID   A0A0H2ZLY6
Organism   Pseudomonas aeruginosa strain PA8281     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 737053..747697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PA8281_RS03495 (PA8281_03283) - 737176..737406 (+) 231 WP_010895513.1 hypothetical protein -
  PA8281_RS03500 (PA8281_03284) - 737502..738554 (+) 1053 WP_003113178.1 pyocin knob domain-containing protein -
  PA8281_RS03505 (PA8281_03285) - 738554..738856 (+) 303 WP_003113177.1 hypothetical protein -
  PA8281_RS03510 (PA8281_03286) - 738853..739083 (+) 231 WP_003113176.1 hypothetical protein -
  PA8281_RS03515 (PA8281_03287) - 739502..740107 (+) 606 WP_003113175.1 aminodeoxychorismate/anthranilate synthase component II -
  PA8281_RS03520 (PA8281_03288) trpD 740109..741158 (+) 1050 WP_003085203.1 anthranilate phosphoribosyltransferase -
  PA8281_RS03525 (PA8281_03289) trpC 741155..741991 (+) 837 WP_003085205.1 indole-3-glycerol phosphate synthase TrpC -
  PA8281_RS03530 (PA8281_03290) crp 742053..742697 (-) 645 WP_003085214.1 cAMP-activated global transcriptional regulator CRP Regulator
  PA8281_RS03535 (PA8281_03291) - 742969..743391 (+) 423 WP_003085219.1 OsmC family protein -
  PA8281_RS03540 (PA8281_03292) speD 743711..744505 (+) 795 WP_003101641.1 adenosylmethionine decarboxylase -
  PA8281_RS03545 (PA8281_03293) coq7 744560..745207 (-) 648 WP_003085224.1 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase -
  PA8281_RS03550 (PA8281_03294) - 745307..745645 (-) 339 WP_019725814.1 histidine triad nucleotide-binding protein -
  PA8281_RS03555 (PA8281_03295) - 745724..747205 (+) 1482 WP_003117981.1 AAA family ATPase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24225.01 Da        Isoelectric Point: 8.0525

>NTDB_id=150833 PA8281_RS03530 WP_003085214.1 742053..742697(-) (crp) [Pseudomonas aeruginosa strain PA8281]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=150833 PA8281_RS03530 WP_003085214.1 742053..742697(-) (crp) [Pseudomonas aeruginosa strain PA8281]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGTGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGAAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(22-114)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZLY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

67.327

94.393

0.636
  crp Haemophilus influenzae Rd KW20

60.396

94.393

0.57
  crp Acinetobacter baumannii D1279779

54.545

92.523

0.505