Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AXW93_RS03380 Genome accession   NZ_CP014866
Coordinates   691112..691756 (-) Length   214 a.a.
NCBI ID   WP_003085214.1    Uniprot ID   A0A0H2ZLY6
Organism   Pseudomonas aeruginosa strain PA_154197     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 686112..696756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXW93_RS03345 (AXW93_03235) - 686235..686465 (+) 231 WP_023085655.1 hypothetical protein -
  AXW93_RS03350 (AXW93_03240) - 686561..687613 (+) 1053 WP_003113178.1 pyocin knob domain-containing protein -
  AXW93_RS03355 (AXW93_03245) - 687613..687915 (+) 303 WP_003113177.1 hypothetical protein -
  AXW93_RS03360 (AXW93_03250) - 687912..688142 (+) 231 WP_003161916.1 hypothetical protein -
  AXW93_RS03365 (AXW93_03255) - 688561..689166 (+) 606 WP_003101640.1 aminodeoxychorismate/anthranilate synthase component II -
  AXW93_RS03370 (AXW93_03260) trpD 689168..690217 (+) 1050 WP_003085203.1 anthranilate phosphoribosyltransferase -
  AXW93_RS03375 (AXW93_03265) trpC 690214..691050 (+) 837 WP_003137410.1 indole-3-glycerol phosphate synthase TrpC -
  AXW93_RS03380 (AXW93_03270) crp 691112..691756 (-) 645 WP_003085214.1 cAMP-activated global transcriptional regulator CRP Regulator
  AXW93_RS03385 (AXW93_03275) - 692028..692450 (+) 423 WP_003085219.1 OsmC family protein -
  AXW93_RS03390 (AXW93_03280) speD 692770..693564 (+) 795 WP_003085223.1 adenosylmethionine decarboxylase -
  AXW93_RS03395 (AXW93_03285) coq7 693619..694266 (-) 648 WP_003085224.1 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase -
  AXW93_RS03400 (AXW93_03290) - 694366..694704 (-) 339 WP_003085225.1 histidine triad nucleotide-binding protein -
  AXW93_RS03405 (AXW93_03295) - 694783..696264 (+) 1482 WP_003121853.1 AAA family ATPase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24225.01 Da        Isoelectric Point: 8.0525

>NTDB_id=150423 AXW93_RS03380 WP_003085214.1 691112..691756(-) (crp) [Pseudomonas aeruginosa strain PA_154197]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=150423 AXW93_RS03380 WP_003085214.1 691112..691756(-) (crp) [Pseudomonas aeruginosa strain PA_154197]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGTGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGGAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(22-114)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZLY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

67.327

94.393

0.636
  crp Haemophilus influenzae Rd KW20

60.396

94.393

0.57
  crp Acinetobacter baumannii D1279779

54.545

92.523

0.505