Detailed information NTG0150063

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: ACX60_RS04505
• Genome accession: NZ_CP012004
• Coordinates: 949322..951754 (+)
• Length: 810 a.a.
• NCBI ID: WP_000472702.1
• Uniprot ID: A0A1E3MCU2
• Organism: Acinetobacter baumannii strain ATCC 17978-mff
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 944322..956754

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACX60_RS04480 (ACX60_04480)	-	944472..945413 (-)	942	WP_000795877.1	hypothetical protein	-
ACX60_RS04485 (ACX60_04485)	-	945670..946155 (+)	486	WP_001985538.1	YaiI/YqxD family protein	-
ACX60_RS04490 (ACX60_04490)	-	946166..947074 (+)	909	WP_001140078.1	DMT family transporter	-
ACX60_RS20090	-	947104..947184 (-)	81	Protein_863	PilZ domain-containing protein	-
ACX60_RS04495 (ACX60_04495)	-	947322..948557 (+)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
ACX60_RS04500 (ACX60_04500)	lolD	948550..949236 (+)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
ACX60_RS04505 (ACX60_04505)	comA/comEC	949322..951754 (+)	2433	WP_000472702.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACX60_RS04510 (ACX60_04510)	-	951707..952690 (-)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
ACX60_RS04515 (ACX60_04515)	sppA	952823..953839 (+)	1017	WP_001286612.1	signal peptide peptidase SppA	-
ACX60_RS04520 (ACX60_04520)	-	953858..954667 (+)	810	WP_000114071.1	alpha/beta fold hydrolase	-
ACX60_RS04525 (ACX60_04525)	purN	954731..955360 (-)	630	WP_000975525.1	phosphoribosylglycinamide formyltransferase	-
ACX60_RS04530 (ACX60_04530)	purM	955357..956427 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92486.72 Da
• Isoelectric Point: 8.5374

>NTDB_id=150063 ACX60_RS04505 WP_000472702.1 949322..951754(+) (comA/comEC) [Acinetobacter baumannii strain ATCC 17978-mff]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINHLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIVSSFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQILMAVPCCLGVLIYTA
FVGFEIPALRTLLSVFIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVFSAGFWLSYGACFILLRIYQTIAQLPEQHFL
SLSSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFVIKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISFAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHSEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=150063 ACX60_RS04505 WP_000472702.1 949322..951754(+) (comA/comEC) [Acinetobacter baumannii strain ATCC 17978-mff]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGCCCCATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCATTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTTTATATAAACCATTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGCCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTGTGTCTAGTTTTAACGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGATTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGTATTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGTTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGAGTAAGGTGTTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTGTAATAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTTTGCCATAATTATTTTATTTTTACCTAAAGGAATTTTGCCCAAAACTTGGGGGATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGACAGGGGCAA
GCCATTTTTTTACAACATTCCGAACAAAACTGGTTAATTGATACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCTGGATGGGAAGCTGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTAGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGGACCTTAAGTTTTGTGTTGGAAAATCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-639)

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Competence protein (Competence) (243-521)

3D structure

• AlphaFold DB: A0A1E3MCU2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.148	100	0.981
comA/comEC	Acinetobacter baumannii strain A118	97.037	100	0.97
comA/comEC	Acinetobacter baylyi ADP1	50.308	100	0.504