Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   ACG33_RS11990 Genome accession   NZ_CP011971
Coordinates   2655986..2657329 (+) Length   447 a.a.
NCBI ID   WP_066921487.1    Uniprot ID   A0A127FBK7
Organism   Steroidobacter denitrificans strain DSM 18526     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2650986..2662329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG33_RS11975 (ACG33_11975) sucD 2651913..2652776 (-) 864 Protein_2364 succinate--CoA ligase subunit alpha -
  ACG33_RS11980 (ACG33_11980) sucC 2652859..2654022 (-) 1164 WP_066921483.1 ADP-forming succinate--CoA ligase subunit beta -
  ACG33_RS11985 (ACG33_11985) - 2654259..2655989 (+) 1731 WP_066921485.1 PAS domain-containing sensor histidine kinase -
  ACG33_RS11990 (ACG33_11990) pilR 2655986..2657329 (+) 1344 WP_066921487.1 sigma-54 dependent transcriptional regulator Regulator
  ACG33_RS11995 (ACG33_11995) - 2657780..2658064 (+) 285 WP_066921489.1 DUF1778 domain-containing protein -
  ACG33_RS12000 (ACG33_12000) - 2658065..2658589 (+) 525 WP_066921491.1 GNAT family N-acetyltransferase -
  ACG33_RS17100 - 2658715..2658912 (+) 198 Protein_2370 type II toxin-antitoxin system RelE/ParE family toxin -
  ACG33_RS12010 (ACG33_12010) - 2659237..2659809 (+) 573 WP_210399053.1 pilin -
  ACG33_RS12015 (ACG33_12015) - 2659906..2661102 (+) 1197 WP_066921495.1 isoprenylcysteine carboxylmethyltransferase family protein -
  ACG33_RS12020 (ACG33_12020) - 2661118..2662323 (+) 1206 WP_168160085.1 serine hydrolase -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49284.73 Da        Isoelectric Point: 6.5833

>NTDB_id=149775 ACG33_RS11990 WP_066921487.1 2655986..2657329(+) (pilR) [Steroidobacter denitrificans strain DSM 18526]
MTKPRALIVDDEPDIRELLAITLERMNLEVTAAATLETAIHALRSGSFDLCLTDMRLPDGDGLDLVQWIQTHAPQTPVAV
ITAHGNVETAVRALKLGAFDFISKPLDIAALRKLITATLKLGESSPKNGQPPRIKLSGQSRAMEQLREMIARVARSQAPV
HIYGESGTGKELVAHLIHDAGVRRDGPFVPVNCGAIPSELMESELFGHKKGSFTGAIADKQGLIQSAEGGTLFLDEIADL
PLHMQVKLLRVIQEKRVRPVGESKEIPIDVRILSATHKNLAAQVADGKFREDLFYRINVIEIRVPPLRERREDIDELVQS
ILARLAPQIGNDALHLTEAARRALRDYHFPGNVRELENVLERAATLCVNDAIDVGDLQLRPKVTQTDTSISSTVAPGEPL
GDALEDIERDAIVRALEQTRYNKTKAAELLGMTFRSLRYRIKKLGIE

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=149775 ACG33_RS11990 WP_066921487.1 2655986..2657329(+) (pilR) [Steroidobacter denitrificans strain DSM 18526]
GTGACGAAACCGCGCGCCCTCATCGTCGATGACGAACCCGACATCCGCGAACTGCTCGCCATCACCCTGGAGCGCATGAA
CCTGGAGGTGACGGCCGCCGCTACATTGGAGACGGCCATCCATGCACTGCGCAGCGGCAGCTTCGATCTGTGTCTCACCG
ACATGCGGCTGCCCGACGGCGATGGCCTGGACCTGGTCCAATGGATCCAGACCCATGCACCGCAGACACCGGTCGCCGTG
ATCACCGCGCATGGCAATGTGGAAACCGCGGTACGCGCACTGAAGCTCGGCGCCTTCGACTTCATCTCCAAGCCCCTGGA
CATCGCCGCGCTGCGCAAGCTGATCACGGCGACGCTCAAGCTCGGTGAATCCAGCCCCAAGAATGGGCAGCCGCCGCGCA
TCAAGCTGTCCGGCCAGTCGCGAGCCATGGAACAGCTGCGCGAAATGATCGCGCGTGTCGCGCGCAGCCAGGCGCCGGTG
CACATCTACGGCGAGTCCGGCACCGGCAAGGAATTGGTGGCCCACTTGATCCACGATGCCGGCGTGCGCCGCGACGGCCC
TTTCGTGCCGGTCAACTGCGGCGCCATCCCCTCCGAACTCATGGAAAGCGAACTGTTCGGGCACAAGAAAGGCAGCTTCA
CCGGCGCGATCGCCGACAAGCAAGGCCTGATCCAATCCGCCGAGGGCGGCACCTTGTTCCTGGACGAGATCGCCGACCTG
CCTCTGCACATGCAGGTGAAGCTGCTGCGGGTCATCCAGGAAAAACGCGTGCGCCCCGTGGGCGAGTCGAAGGAAATTCC
CATCGACGTGCGCATCCTATCGGCCACCCACAAGAACCTCGCGGCACAGGTCGCCGACGGCAAGTTTCGCGAAGATCTGT
TCTATCGCATCAACGTGATCGAGATCCGCGTCCCGCCGCTGCGCGAGCGCCGTGAAGACATCGATGAACTGGTCCAGTCC
ATACTGGCTCGCCTCGCTCCCCAGATCGGCAATGACGCCTTGCATCTCACCGAGGCCGCCCGGCGCGCCCTGCGCGACTA
CCATTTCCCCGGCAATGTGCGCGAACTGGAGAACGTCCTGGAACGTGCCGCCACCCTGTGCGTGAACGACGCCATCGACG
TCGGCGATCTGCAGCTGCGCCCCAAGGTGACTCAGACTGACACTTCCATCTCCAGCACCGTCGCCCCCGGCGAACCCCTG
GGCGATGCCCTGGAGGACATCGAGCGCGACGCCATCGTGCGCGCCCTGGAGCAGACCCGCTACAACAAGACCAAGGCCGC
CGAGTTGCTGGGCATGACCTTCAGGTCGCTGCGCTATCGGATCAAGAAGCTGGGAATCGAGTAG

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(137-302)

Bacterial regulatory protein, Fis family (HTH_8)

(404-444)

Response regulator receiver domain (Response_reg)

(7-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A127FBK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

61.247

100

0.615
  pilR Acinetobacter baumannii strain A118

49.892

100

0.517

Multiple sequence alignment