Detailed information NTG0149673

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: A1R12_RS08415
• Genome accession: NZ_CP014783
• Coordinates: 1700785..1703370 (+)
• Length: 861 a.a.
• NCBI ID: WP_053104470.1
• Uniprot ID: -
• Organism: Bacillus amyloliquefaciens strain B15
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1695785..1708370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A1R12_RS08395 (A1R12_08395)	-	1696582..1697760 (+)	1179	WP_029325912.1	glycine C-acetyltransferase	-
A1R12_RS08400 (A1R12_08400)	miaB	1697903..1699432 (+)	1530	WP_015417500.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
A1R12_RS08405 (A1R12_08405)	ymcA	1699435..1699866 (+)	432	WP_003154113.1	RicAFT regulatory complex protein RicA family protein	Regulator
A1R12_RS08410 (A1R12_08410)	cotE	1700121..1700666 (+)	546	WP_003154111.1	outer spore coat protein CotE	-
A1R12_RS08415 (A1R12_08415)	hexA	1700785..1703370 (+)	2586	WP_053104470.1	DNA mismatch repair protein MutS	Machinery gene
A1R12_RS08420 (A1R12_08420)	hexB	1703386..1705260 (+)	1875	WP_060675478.1	DNA mismatch repair endonuclease MutL	Machinery gene
A1R12_RS08425 (A1R12_08425)	-	1705456..1705929 (+)	474	WP_060675479.1	tyrosine-type recombinase/integrase	-
A1R12_RS08430 (A1R12_08430)	-	1706389..1707027 (+)	639	WP_060675480.1	hypothetical protein	-
A1R12_RS08435 (A1R12_08435)	-	1707103..1707468 (+)	366	WP_060675481.1	HNH endonuclease	-

Sequence

Protein

• Length: 861 a.a.
• Molecular weight: 97723.91 Da
• Isoelectric Point: 5.3034

>NTDB_id=149673 A1R12_RS08415 WP_053104470.1 1700785..1703370(+) (hexA) [Bacillus amyloliquefaciens strain B15]
MASYTPMIQQYLKIKAEHQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGSADKIPMCGVPYHSAAAYIEQLIKK
GYKVAICEQTEDPKAAKGVVKREVVQLITPGTVMDGKGIHESENNFIASVSEFRDGYGLALSDLTTGENLAVFIERIEDV
MSEIYSVGAKEIVVSSKFNEHTAAQLKERCGATISIEDGEITERIEIAKHLPGEELTETFMRLYTYLQKTQKRSLDHLQP
VQVYELEEAMKIDLYSKRNLELTETIRSKSKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRASQIEERQEMVETLINHLF
EREDLRERLKEVYDLERLAGRVAFGNVNARDLIQLKESLKQVPSIKELVGSLNHKKAKERAGLIDPCGDLLDLLEDALHE
NPPLSLKEGNLIKDGYHQKLDEYRDASKNGKDWIARLEQQERAYTGIRSLKVGFNKVFGYYIEVTKANLHLLEDGRYERK
QTLTNAERYITPELKEKEALILEAENNICELEYELFAGLREKVKQFIPRLQRLAKQMSELDALQCFATISENRHYTKPVF
SDNEVKVIEGRHPVVEKVMDSQEYVPNNCLMGDSREMLLITGPNMSGKSTYMRQIALLSIMAQIGCFVPAKEAVLPIFDQ
IFTRIGAADDLISGQSTFMVEMLEAKNAIVNATKDSLILFDEIGRGTSTYDGMALAQAIIEYVHDHIGAKTLFSTHYHEL
TVLEDKLPQLKNVHVRAEEYNGTVVFLHQIKEGAADKSYGIHVAQLAELPDDLISRAQEILKQLEQTGDKPELPAVSEKK
SAVREEPAQLSFFADGEKEQKAPAVSNKEKQVLEAFKSINILDMTPLEAMNEMYKLQKKLK

Nucleotide

• Length: 2586 bp

>NTDB_id=149673 A1R12_RS08415 WP_053104470.1 1700785..1703370(+) (hexA) [Bacillus amyloliquefaciens strain B15]
ATGGCTAGTTACACGCCTATGATACAGCAATACTTGAAGATAAAGGCAGAGCACCAAGATGCCTTTTTATTTTTTCGGCT
TGGTGACTTTTATGAAATGTTTTTTGAAGATGCAAAAAAAGCGTCACAAGAGCTTGAAATTACACTGACAAGCAGAGACG
GAGGTTCGGCTGATAAAATTCCGATGTGCGGCGTGCCTTATCATTCCGCGGCGGCTTATATTGAACAGCTGATTAAAAAG
GGCTATAAAGTGGCGATCTGTGAACAGACGGAAGATCCGAAGGCGGCTAAAGGCGTTGTAAAAAGAGAAGTCGTCCAGCT
GATCACACCGGGAACCGTGATGGATGGAAAAGGCATCCACGAGTCGGAAAACAACTTTATCGCTTCCGTTTCCGAATTTC
GTGACGGATACGGTCTCGCTTTATCGGACTTAACGACCGGAGAAAACCTGGCCGTATTTATTGAGCGGATTGAAGATGTC
ATGTCAGAAATTTACTCAGTCGGCGCAAAGGAAATTGTCGTATCGAGCAAGTTTAACGAACATACAGCTGCTCAGCTGAA
AGAACGGTGCGGCGCCACGATTTCCATCGAAGACGGGGAAATAACAGAACGCATTGAAATCGCAAAGCACTTGCCGGGCG
AAGAGCTGACAGAGACGTTTATGCGTTTATATACGTATTTGCAAAAAACGCAAAAACGGAGCCTGGATCACCTGCAGCCG
GTTCAAGTATATGAATTGGAAGAAGCGATGAAAATTGACCTGTATTCAAAACGGAATCTTGAGCTGACGGAAACGATCCG
TTCGAAAAGCAAAAAAGGGTCATTGCTTTGGCTTTTAGACGAGACGAAAACAGCGATGGGCGGCCGGCTTCTCAAACAAT
GGATTGACCGCCCGCTGATCAGGGCATCCCAAATCGAAGAACGCCAGGAAATGGTCGAGACGCTGATCAATCATCTGTTT
GAGCGTGAAGATCTGCGAGAGCGCCTGAAGGAAGTATACGATTTAGAACGTCTGGCGGGCCGGGTCGCATTCGGAAACGT
CAACGCAAGGGATTTAATTCAGCTGAAAGAATCTTTAAAACAAGTGCCGAGCATCAAAGAGCTTGTAGGGTCTCTTAACC
ATAAAAAAGCAAAAGAACGCGCCGGCTTGATTGATCCGTGCGGAGATTTGCTTGACCTGTTAGAAGATGCCCTTCATGAA
AACCCGCCGTTATCGTTAAAAGAAGGCAATTTAATTAAAGACGGCTATCATCAGAAGCTCGATGAGTACCGTGACGCCAG
CAAAAACGGTAAAGACTGGATTGCCAGACTGGAGCAGCAGGAACGCGCTTATACGGGCATCCGTTCATTAAAGGTCGGTT
TCAATAAAGTGTTCGGCTATTATATTGAAGTCACAAAAGCAAACCTTCATCTGCTTGAAGACGGACGGTATGAGCGGAAG
CAGACCCTCACAAACGCCGAACGGTACATTACGCCGGAATTGAAGGAAAAAGAAGCGCTTATTTTAGAAGCGGAAAACAA
CATCTGCGAGCTGGAATATGAGCTTTTTGCCGGACTGCGTGAAAAGGTGAAACAATTTATTCCGCGCTTGCAGCGTCTTG
CCAAACAAATGAGTGAGCTGGACGCACTGCAATGCTTTGCTACGATCAGTGAAAACAGGCATTACACAAAGCCCGTCTTT
TCTGATAATGAAGTAAAAGTCATTGAAGGGAGACACCCCGTCGTTGAAAAGGTGATGGACAGTCAAGAATACGTGCCGAA
CAACTGCCTGATGGGCGATTCGCGGGAAATGCTCCTGATTACGGGTCCGAATATGTCAGGTAAAAGCACGTATATGAGAC
AGATCGCACTTCTATCGATCATGGCTCAGATCGGCTGTTTTGTGCCCGCAAAAGAAGCGGTTCTGCCGATTTTTGATCAA
ATCTTCACGAGAATCGGGGCAGCGGATGATTTGATTTCCGGACAAAGCACCTTTATGGTGGAAATGCTGGAAGCGAAAAA
CGCGATTGTGAACGCCACAAAAGACAGCCTGATCCTGTTTGATGAAATCGGCCGCGGGACATCAACGTACGACGGAATGG
CGCTGGCACAGGCGATTATTGAATATGTCCATGATCATATCGGCGCTAAAACACTGTTCAGCACGCATTATCATGAGCTG
ACGGTGCTTGAAGATAAGCTTCCTCAGCTGAAAAACGTTCATGTGCGCGCAGAGGAATATAACGGAACGGTCGTGTTTCT
CCATCAAATCAAAGAAGGAGCCGCGGATAAAAGTTACGGCATTCATGTCGCCCAGCTTGCCGAGCTCCCGGACGATCTGA
TCAGCCGCGCGCAGGAGATTTTGAAACAGCTTGAGCAGACGGGAGATAAACCGGAGCTTCCGGCGGTATCTGAGAAAAAG
TCCGCCGTCAGAGAAGAACCGGCACAGCTGTCCTTTTTTGCTGACGGTGAAAAAGAACAGAAGGCACCGGCTGTTTCTAA
TAAAGAAAAACAAGTGCTTGAAGCTTTTAAGTCAATCAATATTCTCGATATGACGCCGCTTGAGGCGATGAATGAAATGT
ACAAGCTGCAAAAAAAATTAAAATAG

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (258-547)

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain II (MutS_II) (125-239)

• MutS domain V (MutS_V) (598-785)

• MutS domain I (MutS_I) (5-116)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	48.191	99.535	0.48
mutS	Pseudomonas stutzeri strain ATCC 17587	38.435	100	0.394