Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   A1R12_RS08420 Genome accession   NZ_CP014783
Coordinates   1703386..1705260 (+) Length   624 a.a.
NCBI ID   WP_060675478.1    Uniprot ID   -
Organism   Bacillus amyloliquefaciens strain B15     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1698386..1710260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A1R12_RS08405 (A1R12_08405) ymcA 1699435..1699866 (+) 432 WP_003154113.1 RicAFT regulatory complex protein RicA family protein Regulator
  A1R12_RS08410 (A1R12_08410) cotE 1700121..1700666 (+) 546 WP_003154111.1 outer spore coat protein CotE -
  A1R12_RS08415 (A1R12_08415) hexA 1700785..1703370 (+) 2586 WP_053104470.1 DNA mismatch repair protein MutS Machinery gene
  A1R12_RS08420 (A1R12_08420) hexB 1703386..1705260 (+) 1875 WP_060675478.1 DNA mismatch repair endonuclease MutL Machinery gene
  A1R12_RS08425 (A1R12_08425) - 1705456..1705929 (+) 474 WP_060675479.1 tyrosine-type recombinase/integrase -
  A1R12_RS08430 (A1R12_08430) - 1706389..1707027 (+) 639 WP_060675480.1 hypothetical protein -
  A1R12_RS08435 (A1R12_08435) - 1707103..1707468 (+) 366 WP_060675481.1 HNH endonuclease -
  A1R12_RS08445 (A1R12_08445) - 1707754..1708901 (+) 1148 WP_155721238.1 IS3 family transposase -
  A1R12_RS08450 (A1R12_08450) - 1708972..1709787 (-) 816 WP_060674177.1 hypothetical protein -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 70194.41 Da        Isoelectric Point: 5.8551

>NTDB_id=149674 A1R12_RS08420 WP_060675478.1 1703386..1705260(+) (hexB) [Bacillus amyloliquefaciens strain B15]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDANSTVIEIDIEEAGLSSIRVLDNGEGMETDDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEIKTSIGEGAGTHLILQGGNIISEQKSSSRKGTEIIVTNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHQGKNLLQTNGNGDVRHVLAAIYGTAVAKKMIPIHVSSLDFEVKGYIALPE
ITRASRNYMSSVINGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHELIRDG
IKEVFQKQRLIPSAQLPKKSAPAPAKNEQQFMTFEESAPERKLPEKTPEPSYSPMKLSSVVKEPEPVIIEEEILPNEADH
DVPPEIGMPEPEAPVSDTPEPEAVAEEIREERVPVMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVGQVE
PEVQDMIVPLTFHYAANEALIIDQHQHELESVGVFLEAFGTNSYIVRCHPAWFPKGEEAELIEEIIQQVLDAKQIDIKKL
REEAAIMMSCKGSIKANRHLRNDEIKALLDDLRRTTDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=149674 A1R12_RS08420 WP_060675478.1 1703386..1705260(+) (hexB) [Bacillus amyloliquefaciens strain B15]
TTGGCAAAAGTCATCCAGCTCTCAGATGAACTCTCGAATAAAATAGCGGCCGGCGAGGTGGTCGAACGGCCTGCCTCAGT
CGTTAAAGAATTGGTGGAAAACGCCATCGACGCAAACAGCACAGTCATTGAAATCGACATAGAGGAAGCGGGGCTTTCGT
CGATTCGGGTGCTCGATAACGGCGAAGGGATGGAAACCGATGATTGCAAGCGGGCTTTCCGCCGCCACGCGACCAGTAAA
ATCAAAGATGAAAACGACCTGTTCCGGGTGAGAACACTCGGTTTCCGCGGAGAAGCTTTGCCAAGTATCGCGTCTGTTTC
TCATCTGGAAATCAAAACGAGCATCGGCGAGGGAGCGGGAACCCATCTCATTCTTCAGGGCGGGAATATCATTTCTGAGC
AGAAATCCTCCAGCAGAAAAGGAACGGAGATTATCGTTACCAACCTGTTTTTCAATACACCCGCCAGATTGAAATATATG
AAAACCGTGCATACGGAGCTCGGCAATATTACGGATGTTGTCAACCGGATCGCTCTTGCGCATCCGGAAGTATCGATCCG
TCTCCGCCATCAGGGGAAAAATCTGCTGCAGACAAACGGTAACGGGGACGTGCGCCATGTGCTGGCCGCAATTTACGGGA
CGGCGGTTGCGAAAAAAATGATACCGATCCATGTCAGCTCGCTTGATTTTGAAGTCAAGGGCTACATTGCGCTTCCGGAA
ATCACGCGTGCATCCAGAAACTACATGTCATCTGTCATTAACGGAAGATACATTAAGAATTTCCCGCTTGTAAAAGCAGT
GCATGAGGGCTATCACACACTTCTGCCGATCGGCCGCCATCCGATTACATTTATCGAAATTACGATGGACCCGATTTTGG
TCGATGTCAATGTCCATCCGTCGAAGCTTGAAGTCCGCCTCAGCAAAGAGACGGAGCTGCATGAGCTGATCCGTGACGGG
ATAAAGGAAGTGTTTCAAAAGCAGCGGCTTATTCCGAGCGCCCAGCTCCCGAAAAAATCAGCGCCGGCACCGGCCAAAAA
CGAACAGCAATTTATGACATTCGAGGAAAGCGCGCCTGAGCGGAAACTTCCTGAAAAAACGCCGGAGCCGTCTTACTCAC
CAATGAAGCTGAGTTCGGTCGTAAAAGAGCCTGAGCCGGTAATAATAGAAGAAGAGATCCTCCCGAATGAAGCGGATCAC
GATGTGCCGCCGGAGATCGGCATGCCGGAACCGGAAGCGCCTGTTTCCGATACTCCGGAACCGGAAGCTGTCGCTGAAGA
AATACGGGAAGAAAGAGTTCCGGTGATGTATCCGATCGGCCAAATGCACGGGACATATATTTTAGCCCAAAACGAAAACG
GCTTGTATATCATTGACCAGCATGCTGCACAAGAACGGATTAAATACGAATATTTCCGGGAGAAAGTCGGGCAGGTCGAG
CCTGAAGTACAGGATATGATCGTGCCGCTCACCTTTCATTATGCGGCAAATGAGGCGCTGATCATTGACCAGCATCAGCA
TGAGCTTGAAAGCGTCGGAGTATTTTTAGAAGCATTCGGCACGAACAGCTACATCGTTCGCTGCCATCCGGCCTGGTTTC
CAAAAGGGGAAGAAGCTGAACTGATTGAAGAAATCATTCAGCAGGTGCTTGACGCCAAACAGATCGATATTAAGAAACTG
CGGGAGGAAGCGGCCATTATGATGAGCTGCAAAGGCTCAATCAAAGCGAACCGCCATTTGCGAAACGACGAAATCAAAGC
GCTCTTGGATGACCTGCGCCGAACGACAGACCCGTTCACATGCCCGCACGGCCGTCCGATCATAATTCACCACAGCACGT
ATGAGATGGAGAAGATGTTTAAGCGTGTGATGTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(439-580)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

46.202

100

0.478

Multiple sequence alignment