Detailed information NTG0149222

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: AS588_RS18665
• Genome accession: NZ_CP014700
• Coordinates: 3856157..3857353 (-)
• Length: 398 a.a.
• NCBI ID: WP_015387437.1
• Uniprot ID: -
• Organism: Bacillus amyloliquefaciens strain S499
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3851157..3862353

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AS588_RS18645 (AS588_18645)	-	3851505..3852827 (-)	1323	WP_015387440.1	ABC transporter substrate-binding protein	-
AS588_RS18650 (AS588_18650)	-	3852824..3853831 (-)	1008	WP_021734062.1	ThiF family adenylyltransferase	-
AS588_RS18655 (AS588_18655)	-	3854063..3855481 (-)	1419	WP_015387438.1	sensor histidine kinase	-
AS588_RS18660 (AS588_18660)	-	3855478..3855690 (-)	213	WP_004393115.1	winged helix-turn-helix domain-containing protein	-
AS588_RS18665 (AS588_18665)	htrA	3856157..3857353 (-)	1197	WP_015387437.1	S1C family serine protease	Regulator
AS588_RS18670 (AS588_18670)	vicX	3857440..3858234 (-)	795	WP_004393110.1	MBL fold metallo-hydrolase	Regulator
AS588_RS18675 (AS588_18675)	-	3858249..3859088 (-)	840	WP_004393108.1	two-component system regulatory protein YycI	-
AS588_RS18680 (AS588_18680)	yycH	3859075..3860433 (-)	1359	WP_004393107.1	two-component system activity regulator YycH	-
AS588_RS18685 (AS588_18685)	walK	3860423..3862258 (-)	1836	WP_004393106.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42674.52 Da
• Isoelectric Point: 8.2793

>NTDB_id=149222 AS588_RS18665 WP_015387437.1 3856157..3857353(-) (htrA) [Bacillus amyloliquefaciens strain S499]
MDYNRDDEQYASEQPRRSKRGYFLSSLIGVIVGAALMAFLMPYWTGGDHGDSSKSTSRRLGSEQVKTVNVNVNDAVTNMV
SRVSDSVVGVLNIQKTDIWGEGGEAGSGSGVIYKKNGNTSYIVTNHHVIEGATEIEISLKDGSRVPAELIGSDRLMDLAV
LKVKSDKIKSAAQFGNSDQVKVGEPVIAIGNPLGLEFAGSVTQGIISGTERAVPVDSNGDGHPDWNAEVLQTDAAINPGN
SGGALMDISGKVVGINSMKIAESAVEGIGLSIPSKLVIPVIQDLEKYGEVRRPFLGIEMKSLTDIASYHWSQTLKLPKGV
KTGAVIMGVDAFSPAGKAGLKKLDVITGFDGHKVNDVVDLRERLYRKKIGDRVNITFYRSGKKKTAEVKLTEADRLQK

Nucleotide

• Length: 1197 bp

>NTDB_id=149222 AS588_RS18665 WP_015387437.1 3856157..3857353(-) (htrA) [Bacillus amyloliquefaciens strain S499]
GTGGATTATAATCGCGATGATGAACAGTACGCCTCCGAACAGCCCCGCCGCAGCAAGAGGGGATACTTTCTATCAAGTCT
GATCGGCGTCATCGTCGGGGCCGCGCTCATGGCTTTCCTGATGCCGTACTGGACAGGCGGAGACCATGGAGACAGCAGCA
AAAGCACCAGCCGGCGTCTCGGCAGCGAACAGGTGAAAACAGTCAACGTAAATGTCAATGACGCTGTCACGAATATGGTC
AGCCGTGTATCGGATTCGGTAGTCGGCGTTCTCAATATCCAAAAGACTGATATTTGGGGAGAGGGCGGCGAAGCGGGAAG
CGGGTCGGGCGTCATTTACAAAAAGAACGGAAACACTTCTTATATCGTAACCAATCACCATGTCATTGAAGGTGCGACTG
AGATTGAGATCAGCCTGAAGGATGGTTCGCGCGTGCCTGCTGAGCTGATCGGGAGCGACCGTCTGATGGATCTCGCGGTA
CTGAAGGTGAAGTCTGATAAAATCAAATCGGCCGCCCAGTTCGGCAATTCTGATCAAGTCAAAGTCGGAGAACCGGTCAT
TGCGATCGGAAATCCGCTCGGACTTGAATTTGCGGGATCAGTGACACAGGGGATCATTTCAGGCACGGAAAGAGCGGTGC
CCGTTGACTCAAACGGCGACGGACATCCGGATTGGAATGCGGAAGTGCTGCAGACCGACGCTGCGATTAATCCCGGCAAC
AGCGGCGGCGCTTTGATGGATATTTCGGGCAAGGTGGTCGGCATCAACTCAATGAAGATCGCTGAATCCGCCGTTGAAGG
AATCGGCCTGTCCATCCCGTCAAAGCTTGTCATTCCCGTTATTCAGGATTTAGAAAAATACGGAGAAGTCCGACGGCCTT
TCCTCGGTATTGAGATGAAATCCTTAACGGATATTGCGAGCTACCATTGGAGCCAGACGCTGAAACTTCCGAAAGGCGTT
AAAACCGGGGCGGTCATTATGGGTGTCGACGCGTTTTCACCGGCCGGAAAAGCGGGTTTGAAAAAGCTCGACGTGATTAC
CGGGTTCGACGGACATAAGGTCAATGACGTTGTGGATCTCCGTGAGCGCCTGTATCGCAAAAAGATCGGCGACCGTGTGA
ACATCACGTTCTACCGTTCGGGAAAGAAAAAAACAGCGGAAGTCAAACTGACAGAAGCGGATCGATTACAGAAATAA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (293-390)

• Trypsin-like peptidase domain (Trypsin_2) (108-255)

• Peptidase family M50 (Peptidase_M50) (324-394)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.687	99.497	0.435
htrA	Streptococcus mitis NCTC 12261	41.192	96.985	0.4
htrA	Streptococcus gordonii str. Challis substr. CH1	40.153	98.241	0.394