Detailed information NTG0149066

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACG06_RS26245
• Genome accession: NZ_CP011857
• Coordinates: 5615170..5616507 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain ATCC 27853
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5610170..5621507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACG06_RS26220 (ACG06_26245)	pgeF	5610313..5611041 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
ACG06_RS26225 (ACG06_26250)	rluD	5611038..5612000 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACG06_RS26230 (ACG06_26255)	-	5612146..5613171 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACG06_RS26235 (ACG06_26260)	-	5613328..5613573 (+)	246	WP_003102591.1	PP0621 family protein	-
ACG06_RS26240 (ACG06_26265)	pilS	5613563..5615155 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ACG06_RS26245 (ACG06_26270)	pilR	5615170..5616507 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACG06_RS26250 (ACG06_26275)	thiO	5616553..5617647 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
ACG06_RS26255 (ACG06_26280)	-	5617782..5618291 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
ACG06_RS26260 (ACG06_26285)	-	5618397..5618903 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACG06_RS26265 (ACG06_26290)	pilV	5618894..5619451 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACG06_RS26270 (ACG06_26295)	pilW	5619448..5620272 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACG06_RS26275 (ACG06_26300)	pilX	5620269..5620856 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=149066 ACG06_RS26245 WP_003094694.1 5615170..5616507(+) (pilR) [Pseudomonas aeruginosa strain ATCC 27853]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=149066 ACG06_RS26245 WP_003094694.1 5615170..5616507(+) (pilR) [Pseudomonas aeruginosa strain ATCC 27853]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCTCAGCG
TCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384