Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BCV59_RS17975 Genome accession   NZ_CP014583
Coordinates   3335361..3335993 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CFSAN004176     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3330361..3340993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BCV59_RS17950 (BCV59_16860) yhfG 3330495..3330662 (+) 168 WP_000736863.1 YhfG family protein -
  BCV59_RS17955 (BCV59_16865) fic 3330652..3331254 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  BCV59_RS17960 (BCV59_16870) pabA 3331286..3331848 (+) 563 Protein_3224 aminodeoxychorismate synthase component 2 -
  BCV59_RS17965 (BCV59_16875) argD 3331934..3333154 (+) 1221 WP_001618902.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BCV59_RS17970 (BCV59_16880) yhfK 3333220..3335310 (-) 2091 WP_032203612.1 YccS/YhfK family putative transporter -
  BCV59_RS17975 (BCV59_16885) crp 3335361..3335993 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BCV59_RS17985 (BCV59_16895) yhfA 3336295..3336699 (+) 405 WP_001148908.1 OsmC family protein -
  BCV59_RS17990 (BCV59_16900) prkB 3336754..3337623 (-) 870 WP_001274680.1 phosphoribulokinase -
  BCV59_RS17995 (BCV59_16905) yheU 3337677..3337895 (-) 219 WP_000907085.1 YheU family protein -
  BCV59_RS18000 (BCV59_16910) yheT 3337889..3338911 (-) 1023 WP_069357422.1 hydrolase -
  BCV59_RS18005 (BCV59_16915) yheS 3338911..3340824 (-) 1914 WP_000634790.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=148723 BCV59_RS17975 WP_000242755.1 3335361..3335993(-) (crp) [Escherichia coli strain CFSAN004176]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=148723 BCV59_RS17975 WP_000242755.1 3335361..3335993(-) (crp) [Escherichia coli strain CFSAN004176]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment