Detailed information NTG0145743

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SpyM6JRS4_RS02140
• Genome accession: NZ_CP011414
• Coordinates: 404973..405974 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes JRS4
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 399973..410974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SpyM6JRS4_RS02115 (SpyM6JRS4_02110)	-	400647..401330 (-)	684	WP_021340135.1	DUF969 domain-containing protein	-
SpyM6JRS4_RS02120 (SpyM6JRS4_02115)	-	401541..402467 (-)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
SpyM6JRS4_RS02125 (SpyM6JRS4_02120)	-	402612..402989 (-)	378	WP_002985686.1	VOC family protein	-
SpyM6JRS4_RS02130 (SpyM6JRS4_02125)	-	403000..403665 (-)	666	WP_011184275.1	NAD(P)H-dependent oxidoreductase	-
SpyM6JRS4_RS02135 (SpyM6JRS4_02130)	-	403714..404799 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
SpyM6JRS4_RS02140 (SpyM6JRS4_02135)	ccpA	404973..405974 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
SpyM6JRS4_RS02145 (SpyM6JRS4_02140)	-	406105..407103 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
SpyM6JRS4_RS02150 (SpyM6JRS4_02145)	-	407105..408439 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
SpyM6JRS4_RS02155 (SpyM6JRS4_02150)	thrS	408861..410804 (+)	1944	WP_011184277.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=145743 SpyM6JRS4_RS02140 WP_002985680.1 404973..405974(+) (ccpA) [Streptococcus pyogenes JRS4]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=145743 SpyM6JRS4_RS02140 WP_002985680.1 404973..405974(+) (ccpA) [Streptococcus pyogenes JRS4]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGATTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559