Detailed information NTG0145730

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: SpyM6JRS4_RS00680
• Genome accession: NZ_CP011414
• Coordinates: 106975..107409 (+)
• Length: 144 a.a.
• NCBI ID: WP_002986542.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes JRS4
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 101975..112409

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SpyM6JRS4_RS00650 (SpyM6JRS4_00650)	-	103644..104009 (+)	366	WP_002986560.1	DUF1033 family protein	-
SpyM6JRS4_RS00655 (SpyM6JRS4_00655)	comYA	104102..105040 (+)	939	WP_002986557.1	competence type IV pilus ATPase ComGA	Machinery gene
SpyM6JRS4_RS00660 (SpyM6JRS4_00660)	comYB	104976..106010 (+)	1035	WP_011184088.1	competence type IV pilus assembly protein ComGB	Machinery gene
SpyM6JRS4_RS00665 (SpyM6JRS4_00665)	comYC	106012..106338 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
SpyM6JRS4_RS00670 (SpyM6JRS4_00670)	comGD	106313..106741 (+)	429	WP_011184089.1	competence type IV pilus minor pilin ComGD	-
SpyM6JRS4_RS00675 (SpyM6JRS4_00675)	comGE	106698..106982 (+)	285	WP_027968839.1	competence type IV pilus minor pilin ComGE	-
SpyM6JRS4_RS00680 (SpyM6JRS4_00680)	comYF	106975..107409 (+)	435	WP_002986542.1	competence type IV pilus minor pilin ComGF	Machinery gene
SpyM6JRS4_RS00685 (SpyM6JRS4_00685)	comGG	107393..107719 (+)	327	WP_002986539.1	competence type IV pilus minor pilin ComGG	-
SpyM6JRS4_RS00690 (SpyM6JRS4_00690)	comYH	107817..108770 (+)	954	WP_021340467.1	class I SAM-dependent methyltransferase	Machinery gene
SpyM6JRS4_RS00695 (SpyM6JRS4_00695)	-	108829..110025 (+)	1197	WP_002986533.1	acetate kinase	-
SpyM6JRS4_RS00700 (SpyM6JRS4_00700)	-	110212..110520 (+)	309	WP_011017251.1	hypothetical protein	-
SpyM6JRS4_RS00705 (SpyM6JRS4_00705)	proC	110603..111373 (-)	771	WP_011184092.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16573.20 Da
• Isoelectric Point: 10.3584

>NTDB_id=145730 SpyM6JRS4_RS00680 WP_002986542.1 106975..107409(+) (comYF) [Streptococcus pyogenes JRS4]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=145730 SpyM6JRS4_RS00680 WP_002986542.1 106975..107409(+) (comYF) [Streptococcus pyogenes JRS4]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCATTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAG
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.985	95.139	0.437
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396