Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   AWB63_RS10195 Genome accession   NZ_CP014144
Coordinates   2178001..2179944 (+) Length   647 a.a.
NCBI ID   WP_038675019.1    Uniprot ID   -
Organism   Streptococcus salivarius strain JF     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2173001..2184944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AWB63_RS10165 (AWB63_10165) argR 2173206..2173634 (+) 429 WP_171963651.1 arginine repressor -
  AWB63_RS10170 (AWB63_10170) - 2173634..2173993 (+) 360 WP_038675011.1 YlbF family regulator -
  AWB63_RS10175 (AWB63_10175) hexA 2174013..2176544 (+) 2532 WP_371212499.1 DNA mismatch repair protein MutS Machinery gene
  AWB63_RS10180 (AWB63_10180) - 2176578..2177033 (-) 456 WP_002886315.1 DUF3021 domain-containing protein -
  AWB63_RS10185 (AWB63_10185) - 2177030..2177467 (-) 438 WP_038675015.1 LytTR family DNA-binding domain-containing protein -
  AWB63_RS10190 (AWB63_10190) - 2177646..2177948 (+) 303 WP_038675017.1 hypothetical protein -
  AWB63_RS10195 (AWB63_10195) hexB 2178001..2179944 (+) 1944 WP_038675019.1 DNA mismatch repair endonuclease MutL Machinery gene
  AWB63_RS10200 (AWB63_10200) - 2180075..2180296 (+) 222 WP_038675022.1 hypothetical protein -
  AWB63_RS10205 (AWB63_10205) ruvA 2180453..2181043 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA Machinery gene
  AWB63_RS10210 (AWB63_10210) - 2181052..2181606 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  AWB63_RS10215 (AWB63_10215) cinA 2181703..2182971 (+) 1269 WP_014633777.1 competence/damage-inducible protein A Machinery gene
  AWB63_RS10220 (AWB63_10220) recA 2183007..2184146 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  AWB63_RS10225 (AWB63_10225) spx 2184314..2184712 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72502.53 Da        Isoelectric Point: 5.2049

>NTDB_id=144475 AWB63_RS10195 WP_038675019.1 2178001..2179944(+) (hexB) [Streptococcus salivarius strain JF]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESESPVSSVENKP
QPSVKQAQRSVDEGDSEHEKLDYKNKSKMKRMLENLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=144475 AWB63_RS10195 WP_038675019.1 2178001..2179944(+) (hexB) [Streptococcus salivarius strain JF]
ATGCCAAAAATCATCGAATTACCTGAGGTGTTAGCCAACCAGATTGCTGCTGGTGAGGTCGTAGAGCGCCCAGCCAGTGT
TGTCAAAGAGTTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGTGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACGAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCATCAATAGCTTCTATCAG
CCACCTAACTATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGATCCTATTTCAACACCGGTTGGAACAAAGATTACCGTTGAAAATCTGTTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTGAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATTAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGACGCTTCCCTATTGCAGTTATTGATATTCAGATTGATCCCTACT
TGGCCGATGTCAATGTTCACCCAACCAAGCAGGAAGTACGTATTTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACCAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTGTATCAGAGTCAGAGTCTCCAGTTTCATCGGTAGAAAATAAACCG
CAACCTTCTGTTAAACAGGCACAACGTTCAGTAGATGAAGGTGATAGCGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAAATCTGGATAATGAGGAAACATCAACCTTCCCTGAATTAGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCTCAAGAACGTGTCAAGTAT
GAGTACTATCGTGAAAAGATTGGTGAGGTTGACAGCAGTTTACAACAGCTTTTGGTTCCTTATCTCTTTGAATTTTCAGG
TTCAGATTACATTAGTTTACAAGAAAAAATGTCCCTTCTTAACCAGGTTGGTATCTATTTAGAACCTTATGGGAACAACA
CTTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTT
CTTTTGACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTGGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTC
ACGGACGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACAAGC
CTACGTGACCTAGGAAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(448-591)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.36

100

0.703