Detailed information NTG0144474

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: AWB63_RS10175
• Genome accession: NZ_CP014144
• Coordinates: 2174013..2176544 (+)
• Length: 843 a.a.
• NCBI ID: WP_371212499.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain JF
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2169013..2181544

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AWB63_RS10155 (AWB63_10155)	-	2169206..2170507 (+)	1302	WP_038675005.1	hypothetical protein	-
AWB63_RS10160 (AWB63_10160)	argS	2171360..2173051 (-)	1692	WP_038675007.1	arginine--tRNA ligase	-
AWB63_RS10165 (AWB63_10165)	argR	2173206..2173634 (+)	429	WP_171963651.1	arginine repressor	-
AWB63_RS10170 (AWB63_10170)	-	2173634..2173993 (+)	360	WP_038675011.1	YlbF family regulator	-
AWB63_RS10175 (AWB63_10175)	hexA	2174013..2176544 (+)	2532	WP_371212499.1	DNA mismatch repair protein MutS	Machinery gene
AWB63_RS10180 (AWB63_10180)	-	2176578..2177033 (-)	456	WP_002886315.1	DUF3021 domain-containing protein	-
AWB63_RS10185 (AWB63_10185)	-	2177030..2177467 (-)	438	WP_038675015.1	LytTR family DNA-binding domain-containing protein	-
AWB63_RS10190 (AWB63_10190)	-	2177646..2177948 (+)	303	WP_038675017.1	hypothetical protein	-
AWB63_RS10195 (AWB63_10195)	hexB	2178001..2179944 (+)	1944	WP_038675019.1	DNA mismatch repair endonuclease MutL	Machinery gene
AWB63_RS10200 (AWB63_10200)	-	2180075..2180296 (+)	222	WP_038675022.1	hypothetical protein	-
AWB63_RS10205 (AWB63_10205)	ruvA	2180453..2181043 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94635.63 Da
• Isoelectric Point: 4.6360

>NTDB_id=144474 AWB63_RS10175 WP_371212499.1 2174013..2176544(+) (hexA) [Streptococcus salivarius strain JF]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQILVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERYG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSHTNVQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=144474 AWB63_RS10175 WP_371212499.1 2174013..2176544(+) (hexA) [Streptococcus salivarius strain JF]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTATCATTCAGCTCAATCCTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAGATTTTGGTCAAGCAACTCAACCTTCTACTTTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACCAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGCGAGCTCAGTCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTGTTGGAAAATGCTAGAACGGGCAAGAAACACGGTTCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGCACTTGGATTGATCGTCCTTTAGTGAATCAGG
CTGCAATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGACCTGACTGAGAGTCTT
AAAGGGGTTTACGATATTGAGCGCTTAGCCAGTCGAGTTTCCTTTGGCAAGGCTAATCCTAAAGATTTGATTCAACTAGG
TCATACCTTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATGATGAGGCCTTGTCACGTCTTTTACAAG
AATTGGATGCTCTGCCAGAATTAGAAAGTCTGATTCGGTCAGCTATTGATCCCGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGCGAGGGGACGTCATGGATTGCGGA
TATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAATCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAATTCAGAGCGCTATGGA
ACCGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTTGAGGCACGTGAAAAGTCATCAACGCTCGAATATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCCATTGCGACAGTCGATGTTCTTC
AGAGCTTGGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATTGTTATTGATCAA
GGTCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCATACCAA
TGTTCAGCTCATCACAGGGCCAAATATGAGTGGTAAATCTACCTATATGCGTCAGTTGGCTTTGTCAGTCGTTATGGCTC
AGATGGGGGCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCTATCTATACACGTATTGGTGCTGCAGAT
GATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGGGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTAGGACGTGGGACAGCCACCTATGACGGTATGGCTCTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTTGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AATTGGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCTGCCACTGAAACGCATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTACGTGATTTGGACATTTACAATAT
GACACCGATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (590-776)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain I (MutS_I) (1-109)

• MutS domain III (MutS_III) (247-537)

• MutS domain II (MutS_II) (117-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.815	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	35.731	100	0.365